7O45
Crystal structure of ADD domain of the human DNMT3B methyltransferase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Isoform 6 of DNA (cytosine-5)-methyltransferase 3B | polymer | 146 | 16556.7 | 4 | UniProt (Q9UBC3) Pfam (PF17980) Pfam (PF21255) | Homo sapiens (Human) | Dnmt3b,DNA methyltransferase HsaIIIB,DNA MTase HsaIIIB,M.HsaIIIB |
| 2 | E, F, G, J, K... (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 3 | H, I, P (A, C) | BROMIDE ION | non-polymer | 79.9 | 3 | Chemie (BR) | |||
| 4 | T, U, V (A, B, C) | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 412 - 554 (UniProt: Q9UBC3)
| PDB | External Database | Details |
|---|---|---|
| Ser 409 | - | expression tag |
| Gly 410 | - | expression tag |
| Ser 411 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 66226.8 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1024.6 | |
| All* | Total formula weight | 67251.4 |
