8SAV
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![BU of 8sav by Molmil](/molmil-images/mine/8sav) | CryoEM structure of VRC01-CH848.0526.25 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.0526.25 gp120, ... | Authors: | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | Deposit date: | 2023-04-02 | Release date: | 2023-04-19 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
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8SAX
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![BU of 8sax by Molmil](/molmil-images/mine/8sax) | CryoEM structure of DH270.UCA-CH848.10.17DT | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ... | Authors: | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | Deposit date: | 2023-04-02 | Release date: | 2023-04-19 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
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8SAZ
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![BU of 8saz by Molmil](/molmil-images/mine/8saz) | CryoEM structure of DH270.I5.6-CH848.10.17 | Descriptor: | CH848.10.17.SOSIP gp41, DH270.I5.6 variable heavy chain, DH270.I5.6 variable light chain, ... | Authors: | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | Deposit date: | 2023-04-02 | Release date: | 2023-04-19 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
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8SB4
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![BU of 8sb4 by Molmil](/molmil-images/mine/8sb4) | CryoEM structure of DH270.1-CH848.10.17 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ... | Authors: | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | Deposit date: | 2023-04-02 | Release date: | 2023-04-19 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
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8SAS
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![BU of 8sas by Molmil](/molmil-images/mine/8sas) | CryoEM structure of DH270.5-CH848.10.17 | Descriptor: | CH848.10.17 gp120, CH848.10.17 gp41, DH270.5 variable heavy chian, ... | Authors: | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | Deposit date: | 2023-04-01 | Release date: | 2023-04-19 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
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8SAQ
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![BU of 8saq by Molmil](/molmil-images/mine/8saq) | CryoEM structure of DH270.6-CH848.0526.25 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.0526.25 gp120, CH848.0526.25 gp41, ... | Authors: | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | Deposit date: | 2023-04-01 | Release date: | 2023-04-19 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
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8SB5
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![BU of 8sb5 by Molmil](/molmil-images/mine/8sb5) | CryoEM structure of DH270.I1.6-CH848.10.17 | Descriptor: | CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, DH270.I1.6 variable heavy chain, ... | Authors: | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | Deposit date: | 2023-04-02 | Release date: | 2023-04-19 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
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8SB2
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![BU of 8sb2 by Molmil](/molmil-images/mine/8sb2) | CryoEM structure of DH270.I2-CH848.10.17 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ... | Authors: | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | Deposit date: | 2023-04-02 | Release date: | 2023-04-19 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
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8SB0
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![BU of 8sb0 by Molmil](/molmil-images/mine/8sb0) | CryoEM structure of DH270.I4.6-CH848.10.17 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ... | Authors: | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | Deposit date: | 2023-04-02 | Release date: | 2023-04-19 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
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6ZBM
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![BU of 6zbm by Molmil](/molmil-images/mine/6zbm) | Structure of the D125N mutant of the catalytic domain of the Bacillus circulans alpha-1,6 Mannanase in complex with an alpha-1,6-alpha-manno-cyclophellitol carbasugar-stabilised trisaccharide inhibitor | Descriptor: | (1~{R},2~{R},3~{R},4~{S},5~{R})-4-[[(1~{S},2~{S},3~{S},4~{R},5~{R})-5-(hydroxymethyl)-2,3,4-tris(oxidanyl)cyclohexyl]oxymethyl]cyclohexane-1,2,3,5-tetrol, 1,2-ETHANEDIOL, Alpha-1,6-mannanase, ... | Authors: | Davies, G.J, Offen, W.A. | Deposit date: | 2020-06-08 | Release date: | 2021-04-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Development of Non-Hydrolysable Oligosaccharide Activity-Based Inactivators for Endoglycanases: A Case Study on alpha-1,6 Mannanases. Chemistry, 27, 2021
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6PSO
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![BU of 6pso by Molmil](/molmil-images/mine/6pso) | Crystal structure of PsS1_19B C77S in complex with iota-neocarratetraose | Descriptor: | 3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose-(1-3)-4-O-sulfo-beta-D-galactopyranose-(1-4)-3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose-(1-3)-4-O-sulfo-beta-D-galactopyranose, CALCIUM ION, CHLORIDE ION, ... | Authors: | Hettle, A.G, Boraston, A.B. | Deposit date: | 2019-07-13 | Release date: | 2019-09-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies. Commun Biol, 2, 2019
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6T9O
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![BU of 6t9o by Molmil](/molmil-images/mine/6t9o) | CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(3,5)P2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Wang, Q, Pike, A.C.W, Grieben, M, Baronina, A, Nasrallah, C, Shintre, C, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | Deposit date: | 2019-10-28 | Release date: | 2019-11-20 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2. Structure, 28, 2020
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3NKN
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![BU of 3nkn by Molmil](/molmil-images/mine/3nkn) | Crystal structure of mouse autotaxin in complex with 14:0-LPA | Descriptor: | (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O. | Deposit date: | 2010-06-20 | Release date: | 2011-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of autotaxin and insight into GPCR activation by lipid mediators Nat.Struct.Mol.Biol., 18, 2011
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8QVU
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![BU of 8qvu by Molmil](/molmil-images/mine/8qvu) | Crystal Structure of ligand ACBI3 in complex with KRAS G12D C118S GDP and pVHL:ElonginC:ElonginB complex | Descriptor: | (2S,4R)-1-[(2S)-2-[4-[4-[(3S)-4-[4-[5-[(4S)-2-azanyl-3-cyano-4-methyl-6,7-dihydro-5H-1-benzothiophen-4-yl]-1,2,4-oxadiazol-3-yl]pyrimidin-2-yl]-3-methyl-1,4-diazepan-1-yl]butoxy]-1,2,3-triazol-1-yl]-3-methyl-butanoyl]-N-[(1R)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]-2-oxidanyl-ethyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | Authors: | Wijaya, A.J, Zollman, D, Farnaby, W, Ciulli, A. | Deposit date: | 2023-10-18 | Release date: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Targeting cancer with small molecule pan-KRAS degraders Biorxiv, 2023
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8SB1
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![BU of 8sb1 by Molmil](/molmil-images/mine/8sb1) | CryoEM structure of DH270.I3-CH848.10.17 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17.SOSIP gp41, ... | Authors: | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | Deposit date: | 2023-04-02 | Release date: | 2023-04-19 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
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8SK7
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![BU of 8sk7 by Molmil](/molmil-images/mine/8sk7) | Cryo-EM structure of designed Influenza HA binder, HA_20, bound to Influenza HA (Strain: Iowa43) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HA_20 minibinder (RFdiffusion-designed), ... | Authors: | Borst, A.J, Bennett, N.R. | Deposit date: | 2023-04-18 | Release date: | 2023-06-14 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | De novo design of protein structure and function with RFdiffusion. Nature, 620, 2023
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8SZA
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![BU of 8sza by Molmil](/molmil-images/mine/8sza) | |
8S90
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![BU of 8s90 by Molmil](/molmil-images/mine/8s90) | |
8SW7
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![BU of 8sw7 by Molmil](/molmil-images/mine/8sw7) | BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody FP1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 Boost 2 gp120, BG505 Boost 2 gp41, ... | Authors: | Pratap, P.P, Antansijevic, A, Ozorowski, G, Ward, A.B. | Deposit date: | 2023-05-17 | Release date: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Focusing antibody responses to the fusion peptide in rhesus macaques. Biorxiv, 2023
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1H83
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![BU of 1h83 by Molmil](/molmil-images/mine/1h83) | STRUCTURE OF POLYAMINE OXIDASE IN COMPLEX WITH 1,8-DIAMINOOCTANE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, OCTANE 1,8-DIAMINE, ... | Authors: | Binda, C, Coda, A, Angelini, R, Federico, R, Ascenzi, P, Mattevi, A. | Deposit date: | 2001-01-24 | Release date: | 2001-01-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Bases for Inhibitor Binding and Catalysis in Polyamine Oxidase Biochemistry, 40, 2001
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8S8Z
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![BU of 8s8z by Molmil](/molmil-images/mine/8s8z) | Cryo-EM structure of octameric human CALHM1 (I109W) in complex with ruthenium red | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calcium homeostasis modulator protein 1, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2) | Authors: | Syrjanen, J.L, Furukawa, H. | Deposit date: | 2023-03-27 | Release date: | 2023-07-26 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red. Nat Commun, 14, 2023
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8SB6
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![BU of 8sb6 by Molmil](/molmil-images/mine/8sb6) | Structure of human BRD2-BD1 bound to a histone H4 acetyl-methyllysine peptide | Descriptor: | Bromodomain containing 2, Histone H4 | Authors: | Connor, L.J, Ekundayo, B.E, Lu-Culligan, W.J, Simon, M.D, Bleichert, F. | Deposit date: | 2023-04-02 | Release date: | 2023-07-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Acetyl-methyllysine marks chromatin at active transcription start sites. Nature, 622, 2023
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1H81
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![BU of 1h81 by Molmil](/molmil-images/mine/1h81) | STRUCTURE OF POLYAMINE OXIDASE IN THE REDUCED STATE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, POLYAMINE OXIDASE, ... | Authors: | Binda, C, Coda, A, Angelini, R, Federico, R, Ascenzi, P, Mattevi, A. | Deposit date: | 2001-01-24 | Release date: | 2001-01-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Bases for Inhibitor Binding and Catalysis in Polyamine Oxidase Biochemistry, 40, 2001
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8SK5
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![BU of 8sk5 by Molmil](/molmil-images/mine/8sk5) | Crystal structure of the SARS-CoV-2 neutralizing VHH 7A9 bound to the spike receptor binding domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, anti-SARS-CoV-2 receptor binding domain VHH | Authors: | Noland, C.L, Pande, K, Zhang, L, Zhou, H, Galli, J, Eddins, M, Gomez-Llorente, Y. | Deposit date: | 2023-04-18 | Release date: | 2023-08-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.011 Å) | Cite: | Discovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants. Sci Rep, 13, 2023
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1H15
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![BU of 1h15 by Molmil](/molmil-images/mine/1h15) | X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus DNA polymerase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA POLYMERASE, ... | Authors: | Lang, H, Jacobsen, H, Ikemizu, S, Andersson, C, Harlos, K, Madsen, L, Hjorth, P, Sondergaard, L, Svejgaard, A, Wucherpfennig, K, Stuart, D.I, Bell, J.I, Jones, E.Y, Fugger, L. | Deposit date: | 2002-07-02 | Release date: | 2002-10-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis Nat.Immunol., 3, 2002
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