8S90
Cryo-EM structure of octameric human CALHM1 (I109W) in complex with ruthenium red (C1)
Summary for 8S90
Entry DOI | 10.2210/pdb8s90/pdb |
EMDB information | 40233 |
Descriptor | Calcium homeostasis modulator protein 1, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2) (2 entities in total) |
Functional Keywords | taste, assembly, calcium homeostasis modulator protein, membrane protein, channel, lipid binding, large-pore channel, ruthenium red |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 8 |
Total formula weight | 279299.84 |
Authors | Syrjanen, J.L.,Furukawa, H. (deposition date: 2023-03-27, release date: 2023-07-26, Last modification date: 2024-05-01) |
Primary citation | Syrjanen, J.L.,Epstein, M.,Gomez, R.,Furukawa, H. Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red. Nat Commun, 14:3821-3821, 2023 Cited by PubMed: 37380652DOI: 10.1038/s41467-023-39388-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.73 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)