PDB: 6151 resultsInfo pagesStatus searchChemie searchBIRD

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7JQB	SARS-CoV-2 Nsp1 and rabbit 40S ribosome complex Descriptor: 40S ribosomal protein S21, 40S ribosomal protein S24, 40S ribosomal protein S26, ... Authors: Yuan, S, Xiong, Y. Deposit date: 2020-08-10 Release date: 2020-12-02 Last modified: 2025-06-04 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA. Mol.Cell, 80, 2020
8UIK	In situ HHT and CHX treated human 80S ribosome with EBP1 (consensus map) Descriptor: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S rRNA, 28S rRNA, ... Authors: Wei, Z, Yong, X. Deposit date: 2023-10-10 Release date: 2025-04-30 Method: ELECTRON MICROSCOPY (2.96 Å) Cite: In situ HHT and CHX treated human 80S ribosome with EBP1 (consensus map) To Be Published
7ZJX	Rabbit 80S ribosome programmed with SECIS and SBP2 Descriptor: 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ... Authors: Hilal, T, Simonovic, M, Spahn, C.M.T. Deposit date: 2022-04-12 Release date: 2022-09-07 Last modified: 2025-10-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Science, 376, 2022
7ZJW	Rabbit 80S ribosome as it decodes the Sec-UGA codon Descriptor: 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ... Authors: Hilal, T, Simonovic, M, Spahn, C.M.T. Deposit date: 2022-04-12 Release date: 2022-10-19 Last modified: 2025-12-17 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Science, 376, 2022
4UG0	STRUCTURE OF THE HUMAN 80S RIBOSOME Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S RIBOSOMAL PROTEIN, ... Authors: Khatter, H, Myasnikov, A.G, Natchiar, S.K, Klaholz, B.P. Deposit date: 2015-03-20 Release date: 2015-06-10 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structure of the human 80S ribosome NATURE, 520, 2015
8R0B	Cryo-EM structure of the cross-exon pre-B+ATP complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-31 Release date: 2024-05-22 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
9C8K	Rabbit Hemorrhagic Disease Virus reinitiation stimulating TURBS RNA bound to rabbit ribosome Descriptor: 18S ribosomal RNA, 40S ribosomal protein S26, 40S ribosomal protein eS19, ... Authors: Sherlock, M.E, Kieft, J.S. Deposit date: 2024-06-12 Release date: 2025-02-19 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: A conserved class of viral RNA structures regulates translation reinitiation through dynamic ribosome interactions. Cell Rep, 44, 2025
8UKB	In situ HHT and CHX treated human hibernating state without E-tRNA 80S ribosome Descriptor: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S rRNA, 28S rRNA, ... Authors: Wei, Z, Yong, X. Deposit date: 2023-10-12 Release date: 2024-11-20 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: In situ human hibernating rotated state 80S ribosome To Be Published
8P03	48S late-stage initiation complex with m6A mRNA Descriptor: 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Guca, E, Lima, L.H.F, Boissier, F, Hashem, Y. Deposit date: 2023-05-09 Release date: 2024-03-20 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (3.04 Å) Cite: N 6 -methyladenosine in 5' UTR does not promote translation initiation. Mol.Cell, 84, 2024
8P09	48S late-stage initiation complex with non methylated mRNA Descriptor: 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Guca, E, Lima, L.H.F, Boissier, F, Hashem, Y. Deposit date: 2023-05-09 Release date: 2024-03-20 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: N 6 -methyladenosine in 5' UTR does not promote translation initiation. Mol.Cell, 84, 2024
5LKS	Structure-function insights reveal the human ribosome as a cancer target for antibiotics Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... Authors: Myasnikov, A.G, Natchiar, S.K, Nebout, M, Hazemann, I, Imbert, V, Khatter, H, Peyron, J.-F, Klaholz, B.P. Deposit date: 2016-07-23 Release date: 2017-04-26 Last modified: 2025-10-01 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structure-function insights reveal the human ribosome as a cancer target for antibiotics. Nat Commun, 7, 2016
9F1C	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-10-02 Method: ELECTRON MICROSCOPY (3.78 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
9F1D	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-10-02 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
9F1B	Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-10-02 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
7MQ9	Cryo-EM structure of the human SSU processome, state pre-A1* Descriptor: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Vanden Broeck, A, Singh, S, Klinge, S. Deposit date: 2021-05-05 Release date: 2021-09-22 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.87 Å) Cite: Nucleolar maturation of the human small subunit processome. Science, 373, 2021
7MQ8	Cryo-EM structure of the human SSU processome, state pre-A1 Descriptor: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Vanden Broeck, A, Singh, S, Klinge, S. Deposit date: 2021-05-05 Release date: 2021-09-22 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Nucleolar maturation of the human small subunit processome. Science, 373, 2021
2BF8	Crystal structure of SUMO modified ubiquitin conjugating enzyme E2- 25K Descriptor: UBIQUITIN-CONJUGATING ENZYME E2-25 KDA, UBIQUITIN-LIKE PROTEIN SMT3C Authors: Pichler, A, Knipscheer, P, Oberhofer, E, Van Dijk, W.J, Korner, R, Velgaard Olsen, J, Jentsch, S, Melchior, F, Sixma, T.K. Deposit date: 2004-12-06 Release date: 2005-02-16 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Sumo Imodification of the Ubiquitin Conjugating Enzyme E2-25K Nat.Struct.Mol.Biol., 12, 2005
7FJI	human Pol III elongation complex Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... Authors: Hou, H, Xu, Y. Deposit date: 2021-08-04 Release date: 2021-10-27 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine. Nat Commun, 12, 2021
7FJJ	human Pol III pre-termination complex Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... Authors: Hou, H, Xu, Y. Deposit date: 2021-08-04 Release date: 2021-10-27 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine. Nat Commun, 12, 2021
3J7O	Structure of the mammalian 60S ribosomal subunit Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... Authors: Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. Deposit date: 2014-08-01 Release date: 2014-09-03 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
3J7Q	Structure of the idle mammalian ribosome-Sec61 complex Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... Authors: Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. Deposit date: 2014-08-01 Release date: 2014-09-03 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
9H6Y	Late-stage 48S Initiation Complex (LS48S IC) guided by the trans-RNA Descriptor: 18S ribosomal RNA, 40S ribosomal protein S24, ATP binding cassette subfamily E member 1, ... Authors: Nguyen, T.T, Hashem, Y, Rocha, R.E.O, Boissier, F, Qian, S.B, Jia, L, Uematsu, S, Gu, Y, Shi, S. Deposit date: 2024-10-25 Release date: 2025-12-10 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Programmable initiation of mRNA translation by trans-RNA. Nat.Biotechnol., 2025
9H74	Late-stage 48S Initiation Complex with eIF3 (LS48S-eIF3 IC) guided by the trans-RNA Descriptor: 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Nguyen, T.T, Hashem, Y, Rocha, R.E.O, Boissier, F, Qian, S.B, Jia, L, Uematsu, S, Gu, Y, Shi, S. Deposit date: 2024-10-25 Release date: 2025-12-10 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Programmable initiation of mRNA translation by trans-RNA. Nat.Biotechnol., 2025
5MQF	Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ... Authors: Bertram, K, Hartmuth, K, Kastner, B. Deposit date: 2016-12-20 Release date: 2017-03-22 Last modified: 2025-07-09 Method: ELECTRON MICROSCOPY (5.9 Å) Cite: Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature, 542, 2017
5XJC	Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y. Deposit date: 2017-04-30 Release date: 2017-07-05 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: An Atomic Structure of the Human Spliceosome Cell, 169, 2017

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