5LKS
Structure-function insights reveal the human ribosome as a cancer target for antibiotics
This is a non-PDB format compatible entry.
Summary for 5LKS
Entry DOI | 10.2210/pdb5lks/pdb |
EMDB information | 4070 |
Descriptor | 28S ribosomal RNA, 60S ribosomal protein L7a, 60S ribosomal protein L9, ... (84 entities in total) |
Functional Keywords | cryoem, human ribosome, 80s, cycloheximide, ribosome |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 80 |
Total formula weight | 3818879.56 |
Authors | Myasnikov, A.G.,Natchiar, S.K.,Nebout, M.,Hazemann, I.,Imbert, V.,Khatter, H.,Peyron, J.-F.,Klaholz, B.P. (deposition date: 2016-07-23, release date: 2017-04-26, Last modification date: 2019-12-11) |
Primary citation | Myasnikov, A.G.,Kundhavai Natchiar, S.,Nebout, M.,Hazemann, I.,Imbert, V.,Khatter, H.,Peyron, J.F.,Klaholz, B.P. Structure-function insights reveal the human ribosome as a cancer target for antibiotics. Nat Commun, 7:12856-12856, 2016 Cited by PubMed: 27665925DOI: 10.1038/ncomms12856 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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