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9ICS	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2',3'-DIDEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DDCTP AND MNCL2 Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-16 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.9 Å) Cite: A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9ICB	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DATP AND COCL2 Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, COBALT (II) ION, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1995-12-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9ICN	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2',3'-DIDEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DDCTP AND MGCL2 Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-16 Release date: 1995-12-16 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3 Å) Cite: A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
6O8Q	HUaa 19bp SYM DNA pH 4.5 Descriptor: DNA (57-MER), DNA-binding protein HU-alpha Authors: Remesh, S.G, Hammel, M. Deposit date: 2019-03-11 Release date: 2020-03-18 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.216 Å) Cite: Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling. Nat Commun, 11, 2020
5ZKM	Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA TCTTCC Descriptor: DNA (5'-D(P*TP*CP*TP*TP*CP*C)-3'), SP_0782 Authors: Lu, G, Li, S, Zhu, J, Yang, Y, Gong, P. Deposit date: 2018-03-24 Release date: 2019-03-27 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins. Nucleic Acids Res., 48, 2020
7Z9L	Phen-DC3 intercalation causes hybrid-to-antiparallel transformation of human telomeric DNA G-quadruplex Descriptor: DNA (5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide Authors: Ghosh, A, Trajkovski, M, Teulade-Fichou, M.P, Gabelica, V, Plavec, J. Deposit date: 2022-03-21 Release date: 2022-08-31 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Phen-DC 3 Induces Refolding of Human Telomeric DNA into a Chair-Type Antiparallel G-Quadruplex through Ligand Intercalation. Angew.Chem.Int.Ed.Engl., 61, 2022
7D0X	NMR solution structures of the DNA minidumbbell formed by 5'-mCTTGXmCTTG-3' Descriptor: DNA (5'-D(*(MCY)P*TP*TP*GP*(3DR)P*(5CM)P*TP*TP*G)-3'), SODIUM ION Authors: Wan, L, Guo, P, Lam, S.L. Deposit date: 2020-09-12 Release date: 2021-02-03 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: 5-Methylcytosine Substantially Enhances the Thermal Stability of DNA Minidumbbells. Chemistry, 27, 2021
6P1H	Cryo-EM Structure of DNA Polymerase Delta Holoenzyme Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ... Authors: Jain, R, Rice, W, Aggarwal, A.K. Deposit date: 2019-05-19 Release date: 2019-10-02 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM structure and dynamics of eukaryotic DNA polymerase delta holoenzyme. Nat.Struct.Mol.Biol., 26, 2019
7D0Z	NMR solution structures of the DNA minidumbbell formed by two CCTG repeats at pH 5 Descriptor: DNA (5'-D(*(DCZ)P*CP*TP*GP*CP*CP*TP*G)-3'), SODIUM ION Authors: Guo, P, Lam, S.L. Deposit date: 2020-09-12 Release date: 2021-02-03 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: 5-Methylcytosine Substantially Enhances the Thermal Stability of DNA Minidumbbells. Chemistry, 27, 2021
6O3T	Structural basis of FOXC2 and DNA interactions Descriptor: DNA (5'-D(*AP*AP*AP*TP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*GP*CP*CP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*GP*GP*CP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*AP*T)-3'), Forkhead box protein C2 Authors: Nam, H.-J, Li, S. Deposit date: 2019-02-27 Release date: 2020-01-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.06 Å) Cite: Crystal Structure of FOXC2 in Complex with DNA Target. Acs Omega, 4, 2019
7D0Y	NMR solution structures of the DNA minidumbbell formed by two CmCTG repeats at pH 5 Descriptor: DNA (5'-D(*(DCZ)P*(5CM)P*TP*GP*CP*(5CM)P*TP*G)-3'), SODIUM ION Authors: Wan, L, Guo, P, Lam, S.L. Deposit date: 2020-09-12 Release date: 2021-02-03 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: 5-Methylcytosine Substantially Enhances the Thermal Stability of DNA Minidumbbells. Chemistry, 27, 2021
5IKN	Crystal Structure of the T7 Replisome in the Absence of DNA Descriptor: DNA primase/helicase, DNA-directed DNA polymerase, Thioredoxin-1 Authors: Wallen, J.R, Ellenberger, T. Deposit date: 2016-03-03 Release date: 2016-12-07 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (4.802 Å) Cite: Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome. Structure, 25, 2017
8V6J	DNA elongation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... Authors: Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. Deposit date: 2023-12-01 Release date: 2023-12-20 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (11.11 Å) Cite: A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8V6I	DNA elongation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... Authors: Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. Deposit date: 2023-12-01 Release date: 2023-12-20 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (14.06 Å) Cite: A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
6MU5	Bst DNA polymerase I TNA/DNA binary complex Descriptor: DNA (5'-D(P*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA polymerase I, SULFATE ION, ... Authors: Jackson, L.N, Chim, N, Chaput, J.C. Deposit date: 2018-10-22 Release date: 2019-06-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.912 Å) Cite: Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase. Nucleic Acids Res., 47, 2019
8G9F	Complete auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... Authors: Mullins, E.A, Chazin, W.J, Eichman, B.F. Deposit date: 2023-02-21 Release date: 2023-04-12 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
6NJQ	Structure of TBP-Hoogsteen containing DNA complex Descriptor: DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*CP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*GP*TP*TP*TP*AP*TP*AP*GP*C)-3'), TATA-box-binding protein 1 Authors: Schumacher, M.A, Stelling, A. Deposit date: 2019-01-04 Release date: 2019-10-30 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Infrared Spectroscopic Observation of a G-C+Hoogsteen Base Pair in the DNA:TATA-Box Binding Protein Complex Under Solution Conditions. Angew.Chem.Int.Ed.Engl., 58, 2019
6R9G	Structural basis of transcription inhibition by the DNA mimic Ocr protein of bacteriophage T7 Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Ye, F.Z, Zhang, X.D. Deposit date: 2019-04-03 Release date: 2020-02-26 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis of transcription inhibition by the DNA mimic protein Ocr of bacteriophage T7. Elife, 9, 2020
6MC4	Crystal structure of a tetrameric DNA fold-back quadruplex Descriptor: CALCIUM ION, DNA (5'-D(*CP*GP*TP*CP*AP*GP*GP*CP*G)-3'), POTASSIUM ION Authors: Chu, B, Paukstelis, P.J. Deposit date: 2018-08-30 Release date: 2018-11-14 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Crystal Structure of a Tetrameric DNA Fold-Back Quadruplex. J. Am. Chem. Soc., 140, 2018
4RTJ	A non-cognate complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with DNA and Sinefungin Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*TP*CP*TP*AP*GP*AP*TP*CP*TP*AP*GP*A)-3'), DNA adenine methylase, ... Authors: Horton, J.R, Cheng, X. Deposit date: 2014-11-15 Release date: 2015-04-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression. Nucleic Acids Res., 43, 2015
4RTQ	Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoHcy and a 5-bp non-canonical site (GTTTA ) Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*TP*TP*AP*AP*AP*CP*TP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*GP*TP*TP*TP*AP*AP*G)-3'), ... Authors: Horton, J.R, Cheng, X. Deposit date: 2014-11-15 Release date: 2015-04-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.997 Å) Cite: Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression. Nucleic Acids Res., 43, 2015
2STW	SOLUTION NMR STRUCTURE OF THE HUMAN ETS1/DNA COMPLEX, RESTRAINED REGULARIZED MEAN STRUCTURE Descriptor: DNA (5'-D(*TP*CP*GP*AP*AP*CP*TP*TP*CP*CP*GP*GP*CP*TP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*AP*GP*CP*CP*GP*GP*AP*AP*GP*TP*TP*CP*GP*A)-3'), ETS1 Authors: Clore, G.M, Werner, M.H, Gronenborn, A.M. Deposit date: 1996-08-05 Release date: 1997-03-12 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Correction of the NMR structure of the ETS1/DNA complex. J.Biomol.NMR, 10, 1997
6T8H	Cryo-EM structure of the DNA-bound PolD-PCNA processive complex from P. abyssi Descriptor: DNA polymerase II small subunit, DNA polymerase sliding clamp, DNA primer, ... Authors: Madru, C, Raia, P, Hugonneau Beaufet, I, Pehau-Arnaudet, G, England, P, Lindhal, E, Delarue, M, Carroni, M, Sauguet, L. Deposit date: 2019-10-24 Release date: 2020-03-04 Last modified: 2020-04-08 Method: ELECTRON MICROSCOPY (3.77 Å) Cite: Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA. Nat Commun, 11, 2020
6NCM	Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead-like (FHL) DNA sequence Descriptor: DNA (5'-D(*AP*TP*AP*GP*CP*GP*TP*CP*TP*TP*AP*GP*CP*AP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*TP*GP*CP*TP*AP*AP*GP*AP*CP*GP*CP*TP*A)-3'), Forkhead box protein N3, ... Authors: Rogers, J.M, Jarrett, S.M, Seegar, T.C, Waters, C.T, Hallworth, A.N, Blacklow, S.C, Bulyk, M.L. Deposit date: 2018-12-11 Release date: 2019-02-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.704 Å) Cite: Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes. Mol. Cell, 74, 2019
6NCE	Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead DNA sequence Descriptor: DNA (5'-D(*AP*CP*AP*TP*TP*GP*TP*TP*TP*AP*CP*TP*TP*AP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*TP*AP*AP*GP*TP*AP*AP*AP*CP*AP*AP*TP*G)-3'), Forkhead box protein N3, ... Authors: Rogers, J.M, Jarrett, S.M, Seegar, T.C, Waters, C.T, Hallworth, A.N, Blacklow, S.C, Bulyk, M.L. Deposit date: 2018-12-11 Release date: 2019-02-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.598 Å) Cite: Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes. Mol. Cell, 74, 2019

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