8V6J

DNA elongation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase

Summary for 8V6J

Entry DOI	10.2210/pdb8v6j/pdb
EMDB information	42993
Descriptor	DNA polymerase alpha catalytic subunit, IRON/SULFUR CLUSTER, DNA polymerase alpha subunit B, ... (10 entities in total)
Functional Keywords	primase, dna polymerase, chimeric rna-dna primer, rna/dna hybrid, dna replication, dna synthesis, replication, transferase-dna-rna complex, transferase/dna/rna
Biological source	Xenopus laevis (African clawed frog) More
Total number of polymer chains	6
Total formula weight	328230.34
Authors	Mullins, E.A.,Durie, C.L.,Ohi, M.D.,Chazin, W.J.,Eichman, B.F. (deposition date: 2023-12-01, release date: 2023-12-20, Last modification date: 2024-03-27)
Primary citation	Mullins, E.A.,Salay, L.E.,Durie, C.L.,Bradley, N.P.,Jackman, J.E.,Ohi, M.D.,Chazin, W.J.,Eichman, B.F. A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38491139 DOI: 10.1038/s41594-024-01227-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (11.11 Å)

Structure validation