PDB: 47011 resultsInfo pagesStatus searchChemie searchBIRD

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3NBN	Crystal structure of a dimer of Notch Transcription Complex trimers on HES1 DNA Descriptor: DNA, HES1 promoter, Mastermind-like protein 1, ... Authors: Arnett, K.L, Blacklow, S.C. Deposit date: 2010-06-03 Release date: 2010-11-03 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3.45 Å) Cite: Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes. Nat.Struct.Mol.Biol., 17, 2010
8QQI	E.coli DNA gyrase in complex with 217 bp substrate DNA and LEI-800 Descriptor: DNA gyrase subunit A, DNA gyrase subunit B, MAGNESIUM ION, ... Authors: Ghilarov, D, Martin, N.I, van der Stelt, M. Deposit date: 2023-10-04 Release date: 2024-06-19 Last modified: 2024-09-18 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria. Nat.Chem., 16, 2024
7PP4	Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme comprising sigma factor SigB Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Brodolin, K. Deposit date: 2021-09-13 Release date: 2022-09-21 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.84 Å) Cite: Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14, 2023
2OXV	Structure of the A138T promiscuous mutant of the EcoRI restriction endonuclease bound to its cognate recognition site. Descriptor: DNA (5'-D(*TP*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), Type II restriction enzyme EcoRI Authors: Sapienza, P.J, Rosenberg, J.M, Jen-Jacobson, L. Deposit date: 2007-02-21 Release date: 2007-10-23 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural and thermodynamic basis for enhanced DNA binding by a promiscuous mutant EcoRI endonuclease. Structure, 15, 2007
6RQT	RNA Polymerase I-tWH-Rrn3-DNA Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Mueller, C.W, Sadian, Y, Tafur, L. Deposit date: 2019-05-16 Release date: 2019-12-11 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (4 Å) Cite: Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
6RFL	Structure of the complete Vaccinia DNA-dependent RNA polymerase complex Descriptor: DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... Authors: Grimm, C, Hillen, S.H, Bedenk, K, Bartuli, J, Neyer, S, Zhang, Q, Huettenhofer, A, Erlacher, M, Dienemann, C, Schlosser, A, Urlaub, H, Boettcher, B, Szalay, A.A, Cramer, P, Fischer, U. Deposit date: 2019-04-15 Release date: 2019-12-11 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes. Cell, 179, 2019
7Q59	Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme dimer comprising sigma factor SigB Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Brodolin, K. Deposit date: 2021-11-03 Release date: 2022-11-16 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (4.36 Å) Cite: Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14, 2023
6WMU	E. coli RNAPs70-SspA-gadA DNA complex Descriptor: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... Authors: Travis, B.A, Brennan, R.G, Schumacher, M.A. Deposit date: 2020-04-21 Release date: 2020-11-11 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
6RRD	RNA Polymerase I Pre-initiation complex DNA opening intermediate 1 Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Mueller, C.W, Sadian, Y, Tafur, L. Deposit date: 2019-05-17 Release date: 2019-12-11 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
6RUI	RNA Polymerase I Pre-initiation complex DNA opening intermediate 2 Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Mueller, C.W, Sadian, Y, Tafur, L. Deposit date: 2019-05-28 Release date: 2019-12-11 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
1TRR	TANDEM BINDING IN CRYSTALS OF A TRP REPRESSOR/OPERATOR HALF-SITE COMPLEX Descriptor: DNA (5'-D(*AP*GP*CP*GP*TP*AP*CP*TP*AP*GP*TP*AP*CP*GP*CP*T)-3'), PROTEIN (TRP REPRESSOR), TRYPTOPHAN Authors: Lawson, C.L, Carey, J. Deposit date: 1993-10-21 Release date: 1993-10-21 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Tandem binding in crystals of a trp repressor/operator half-site complex. Nature, 366, 1993
7RSS	Kod-RI incorporating DNA, n+2 Descriptor: DNA polymerase, Primer, Template Authors: Hajjar, M, Chim, N, Chaput, J.C. Deposit date: 2021-08-11 Release date: 2022-08-24 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
8F1J	SigN RNA polymerase early-melted intermediate bound to mismatch DNA fragment dhsU36mm2 (-12A) Descriptor: DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Mueller, A.U, Chen, J, Darst, S.A. Deposit date: 2022-11-05 Release date: 2023-04-05 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: A general mechanism for transcription bubble nucleation in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
8F1K	SigN RNA polymerase early-melted intermediate bound to full duplex DNA fragment dhsU36 (-12T) Descriptor: DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Mueller, A.U, Chen, J, Darst, S.A. Deposit date: 2022-11-05 Release date: 2023-04-05 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: A general mechanism for transcription bubble nucleation in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
6GYM	Structure of a yeast closed complex with distorted DNA (CCdist) Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. Deposit date: 2018-06-30 Release date: 2018-12-05 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (6.7 Å) Cite: Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
4CS5	Crystal Structure of PCNA from Litopenaeus vannamei Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN Authors: Carrasco-Miranda, J.S, Lopez-Zavala, A.A, De-La-Mora, E, Rudino-Pinera, E, Brieba, L.G, Sotelo-Mundo, R.R. Deposit date: 2014-03-04 Release date: 2014-04-23 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal Structure of the Shrimp Proliferating Cell Nuclear Antigen: Structural Complementarity with Wssv DNA Polymerase Pip-Box. Plos One, 9, 2014
6WMR	F. tularensis RNAPs70-(MglA-SspA)-iglA DNA complex Descriptor: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... Authors: Travis, B.A, Brennan, R.G, Schumacher, M.A. Deposit date: 2020-04-21 Release date: 2020-11-11 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.46 Å) Cite: Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
4WLW	CRYSTAL STRUCTURE OF THE AG(I) (ACTIVATOR) FORM OF E. COLI CUER, A COPPER EFFLUX REGULATOR, BOUND TO COPA PROMOTER DNA Descriptor: DNA NON-TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP *DTP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DGP*DCP*DTP*DGP*DGP*DAP *DAP*DGP*DGP*DTP*DC)-3, DNA TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP*DTP *DTP*DCP*DCP*DAP*DGP*DCP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DAP *DGP*DGP*DTP*DC)-3, HTH-type transcriptional regulator CueR, ... Authors: Philips, S.J, Canalizo-Hernandez, M, Mondragon, A, O'Halloran, T.V. Deposit date: 2014-10-08 Release date: 2015-09-02 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.8 Å) Cite: TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter. Science, 349, 2015
1CZ0	INTRON ENCODED HOMING ENDONUCLEASE I-PPOI/DNA COMPLEX LACKING CATALYTIC METAL ION Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), INTRON-ENCODED HOMING ENDONUCLEASE I-PPOI, SODIUM ION, ... Authors: Galburt, E.A, Chevalier, B, Jurica, M.S, Flick, K.E, Stoddard, B.L. Deposit date: 1999-08-31 Release date: 1999-11-19 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A novel endonuclease mechanism directly visualized for I-PpoI. Nat.Struct.Biol., 6, 1999
6GYL	Structure of a yeast closed complex with distorted DNA (core CCdist) Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. Deposit date: 2018-06-30 Release date: 2018-12-05 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
7T02	Cryo-EM structure of DNMT5 pseudo-ternary complex solved by incubation with hemimethylated DNA and SAM Descriptor: DNA (5'-D(*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*CP*A)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*G)-3'), DNA repair protein Rad8, ... Authors: Wang, J, Patel, D.J. Deposit date: 2021-11-29 Release date: 2022-02-23 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance. Mol.Cell, 82, 2022
7NVT	RNA polymerase II core pre-initiation complex with closed promoter DNA in distal position Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Aibara, S, Schilbach, S, Cramer, P. Deposit date: 2021-03-16 Release date: 2021-05-05 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
7NVU	RNA polymerase II core pre-initiation complex with open promoter DNA Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Aibara, S, Schilbach, S, Cramer, P. Deposit date: 2021-03-16 Release date: 2021-05-05 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
7NVS	RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Aibara, S, Schilbach, S, Cramer, P. Deposit date: 2021-03-16 Release date: 2021-05-05 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
5XFR	Ternary complex of MTF2, DNA and histone Descriptor: DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), Metal-response element-binding transcription factor 2, Peptide from Histone H3.1, ... Authors: Wang, Z, Li, H. Deposit date: 2017-04-11 Release date: 2017-09-13 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Polycomb-like proteins link the PRC2 complex to CpG islands Nature, 549, 2017

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