8F1K
SigN RNA polymerase early-melted intermediate bound to full duplex DNA fragment dhsU36 (-12T)
Summary for 8F1K
Entry DOI | 10.2210/pdb8f1k/pdb |
EMDB information | 28786 28790 28791 |
Descriptor | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... (10 entities in total) |
Functional Keywords | promoter-bound, initiation, dna melting, transcription bubble nucleation, transcription, transcription-dna complex, transcription/dna |
Biological source | Escherichia coli More |
Total number of polymer chains | 10 |
Total formula weight | 491154.11 |
Authors | Mueller, A.U.,Chen, J.,Darst, S.A. (deposition date: 2022-11-05, release date: 2023-04-05, Last modification date: 2024-06-19) |
Primary citation | Mueller, A.U.,Chen, J.,Wu, M.,Chiu, C.,Nixon, B.T.,Campbell, E.A.,Darst, S.A. A general mechanism for transcription bubble nucleation in bacteria. Proc.Natl.Acad.Sci.USA, 120:e2220874120-e2220874120, 2023 Cited by PubMed: 36972428DOI: 10.1073/pnas.2220874120 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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