7Q59
Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme dimer comprising sigma factor SigB
Summary for 7Q59
Entry DOI | 10.2210/pdb7q59/pdb |
Related | 7PP4 7Q4U |
EMDB information | 13579 13817 13829 |
Descriptor | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (7 entities in total) |
Functional Keywords | dna-dependent rna polymerase, alternative sigma, transcription |
Biological source | Mycobacterium tuberculosis H37Rv More |
Total number of polymer chains | 12 |
Total formula weight | 806220.76 |
Authors | Brodolin, K. (deposition date: 2021-11-03, release date: 2022-11-16, Last modification date: 2024-07-17) |
Primary citation | Morichaud, Z.,Trapani, S.,Vishwakarma, R.K.,Chaloin, L.,Lionne, C.,Lai-Kee-Him, J.,Bron, P.,Brodolin, K. Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14:484-, 2023 Cited by DOI: 10.1038/s41467-023-36113-yPDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.36 Å) |
Structure validation
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