7PP4

Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme comprising sigma factor SigB

Summary for 7PP4

• Entry DOI: 10.2210/pdb7pp4/pdb
• EMDB information: 13579
• Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (7 entities in total)
• Functional Keywords: dna-dependent rna polymerase, alternative sigma, transcription
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); More
• Total number of polymer chains: 6
• Total formula weight: 403469.85

Authors

Brodolin, K. (deposition date: 2021-09-13, release date: 2022-09-21)

• Primary citation: Morichaud, Z.,Trapani, S.,Vishwakarma, R.,Chaloin, L.,Lionne, C.,Lai-Kee-Him, J.,Bron, P.,Brodolin, K.; Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization; Biorxiv, 2022; DOI: 10.1101/2022.07.04.498644

Experimental method

ELECTRON MICROSCOPY (3.84 Å)