7PP4

Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme comprising sigma factor SigB

Summary for 7PP4

Entry DOI	10.2210/pdb7pp4/pdb
EMDB information	13579
Descriptor	DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (7 entities in total)
Functional Keywords	dna-dependent rna polymerase, alternative sigma, transcription
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) More
Total number of polymer chains	6
Total formula weight	403469.85
Authors	Brodolin, K. (deposition date: 2021-09-13, release date: 2022-09-21, Last modification date: 2024-07-17)
Primary citation	Morichaud, Z.,Trapani, S.,Vishwakarma, R.K.,Chaloin, L.,Lionne, C.,Lai-Kee-Him, J.,Bron, P.,Brodolin, K. Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14:484-, 2023 Cited by DOI: 10.1038/s41467-023-36113-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.84 Å)

Structure validation