6ND6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nd6 by Molmil](/molmil-images/mine/6nd6) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with erythromycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.85A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svetlov, M.S, Plessa, E, Chen, C.-W, Bougas, A, Krokidis, M.G, Dinos, G.P, Polikanov, Y.S. | Deposit date: | 2018-12-13 | Release date: | 2019-02-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition. RNA, 25, 2019
|
|
6ND4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nd4 by Molmil](/molmil-images/mine/6nd4) | Conformational switches control early maturation of the eukaryotic small ribosomal subunit | Descriptor: | 18S rRNA 5' domain start, 5'ETS rRNA, Bud21, ... | Authors: | Hunziker, M, Barandun, J, Klinge, S. | Deposit date: | 2018-12-13 | Release date: | 2019-06-19 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Conformational switches control early maturation of the eukaryotic small ribosomal subunit. Elife, 8, 2019
|
|
6NDK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ndk by Molmil](/molmil-images/mine/6ndk) | Structure of ASLSufA6 A37.5 bound to the 70S A site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Nguyen, H.T, Hoffer, E.D, Dunham, C.M. | Deposit date: | 2018-12-13 | Release date: | 2019-02-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.64 Å) | Cite: | Importance of a tRNA anticodon loop modification and a conserved, noncanonical anticodon stem pairing intRNACGGProfor decoding J. Biol. Chem., 294, 2019
|
|
6ND5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nd5 by Molmil](/molmil-images/mine/6nd5) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with chloramphenicol and bound to mRNA and A-, P-, and E-site tRNAs at 2.60A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svetlov, M.S, Plessa, E, Chen, C.-W, Bougas, A, Krokidis, M.G, Dinos, G.P, Polikanov, Y.S. | Deposit date: | 2018-12-13 | Release date: | 2019-03-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition. RNA, 25, 2019
|
|
6N9F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n9f by Molmil](/molmil-images/mine/6n9f) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic ACCA-DPhe and bound to mRNA and P-site tRNA at 3.7A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ... | Authors: | Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S. | Deposit date: | 2018-12-03 | Release date: | 2018-12-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site. Nucleic Acids Res., 47, 2019
|
|
6N9E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n9e by Molmil](/molmil-images/mine/6n9e) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic CC-Pmn and bound to mRNA and P-site tRNA at 3.7A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ... | Authors: | Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S. | Deposit date: | 2018-12-03 | Release date: | 2018-12-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site. Nucleic Acids Res., 47, 2019
|
|
6I7V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6i7v by Molmil](/molmil-images/mine/6i7v) | Ribosomal protein paralogs bL31 and bL36 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | Authors: | Pulk, A, Cate, J.H.D, Remme, J, Lilleorg, S, Reier, K, Peil, L, Liiv, A, Tammsalu, T. | Deposit date: | 2018-11-19 | Release date: | 2018-12-05 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Bacterial ribosome heterogeneity: Changes in ribosomal protein composition during transition into stationary growth phase. Biochimie, 156, 2018
|
|
6I7O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6i7o by Molmil](/molmil-images/mine/6i7o) | The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways recognition. | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Tesina, P, Cheng, J, Becker, T, Beckmann, R. | Deposit date: | 2018-11-16 | Release date: | 2019-01-16 | Last modified: | 2019-03-13 | Method: | ELECTRON MICROSCOPY (5.3 Å) | Cite: | Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways. EMBO J., 38, 2019
|
|
6I5Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6i5y by Molmil](/molmil-images/mine/6i5y) | Crystal structure of E. coli tyrRS in complex with 5'-O-(N-L-tyrosyl)sulfamoyl-adenosine | Descriptor: | 1,2-ETHANEDIOL, 5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE, Tyrosine--tRNA ligase | Authors: | De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D. | Deposit date: | 2018-11-15 | Release date: | 2019-04-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases. Eur.J.Med.Chem., 173, 2019
|
|
6N1D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n1d by Molmil](/molmil-images/mine/6n1d) | X-ray Crystal complex showing Spontaneous Ribosomal Translocation of mRNA and tRNAs into a Chimeric Hybrid State | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Noller, H.F, Donohue, J.P, Lancaster, L, Zhou, J. | Deposit date: | 2018-11-08 | Release date: | 2019-04-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Spontaneous ribosomal translocation of mRNA and tRNAs into a chimeric hybrid state. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
6IP6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ip6 by Molmil](/molmil-images/mine/6ip6) | Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | Deposit date: | 2018-11-02 | Release date: | 2019-05-29 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
|
|
6IP8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ip8 by Molmil](/molmil-images/mine/6ip8) | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | Deposit date: | 2018-11-02 | Release date: | 2019-05-29 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
|
|
6IP5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ip5 by Molmil](/molmil-images/mine/6ip5) | Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | Deposit date: | 2018-11-02 | Release date: | 2019-05-29 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
|
|
6MTE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mte by Molmil](/molmil-images/mine/6mte) | Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state) | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | Deposit date: | 2018-10-19 | Release date: | 2018-11-21 | Last modified: | 2019-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
|
|
6MTB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mtb by Molmil](/molmil-images/mine/6mtb) | Rabbit 80S ribosome with P- and Z-site tRNAs (unrotated state) | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | Deposit date: | 2018-10-19 | Release date: | 2018-11-21 | Last modified: | 2019-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
|
|
6MTC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mtc by Molmil](/molmil-images/mine/6mtc) | Rabbit 80S ribosome with Z-site tRNA and IFRD2 (unrotated state) | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | Deposit date: | 2018-10-19 | Release date: | 2018-11-21 | Last modified: | 2019-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
|
|
6MTD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mtd by Molmil](/molmil-images/mine/6mtd) | Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel) | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | Deposit date: | 2018-10-19 | Release date: | 2018-11-21 | Last modified: | 2019-05-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
|
|
6MPI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mpi by Molmil](/molmil-images/mine/6mpi) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGU-codon in the A-site and paromomycin | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Cantara, W.A, DeMirci, H, Agris, P.F. | Deposit date: | 2018-10-07 | Release date: | 2019-04-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.33 Å) | Cite: | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
|
|
6MPF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mpf by Molmil](/molmil-images/mine/6mpf) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGC-codon in the A-site and paromomycin | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Cantara, W.A, DeMirci, H, Agris, P.F. | Deposit date: | 2018-10-05 | Release date: | 2019-04-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.33 Å) | Cite: | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
|
|
6HTQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6htq by Molmil](/molmil-images/mine/6htq) | |
6HRM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hrm by Molmil](/molmil-images/mine/6hrm) | E. coli 70S d2d8 stapled ribosome | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | Authors: | Schmied, W.H, Tnimov, Z, Uttamapinant, C, Rae, C.D, Fried, S.D, Chin, J.W. | Deposit date: | 2018-09-27 | Release date: | 2018-12-19 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Controlling orthogonal ribosome subunit interactions enables evolution of new function. Nature, 564, 2018
|
|
6MKN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mkn by Molmil](/molmil-images/mine/6mkn) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Cantara, W.A, DeMirci, H, Agris, P.F. | Deposit date: | 2018-09-25 | Release date: | 2019-04-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
|
|
6HHQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hhq by Molmil](/molmil-images/mine/6hhq) | Crystal structure of compound C45 bound to the yeast 80S ribosome | Descriptor: | (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ... | Authors: | Pellegrino, S, Vanderwal, C.D, Yusupov, M. | Deposit date: | 2018-08-28 | Release date: | 2019-02-20 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (3.10000038 Å) | Cite: | Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome. Nucleic Acids Res., 47, 2019
|
|
6HCQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hcq by Molmil](/molmil-images/mine/6hcq) | Structure of the rabbit collided di-ribosome (collided monosome) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2018-08-16 | Release date: | 2018-10-17 | Last modified: | 2018-11-14 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
|
|
6HCJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hcj by Molmil](/molmil-images/mine/6hcj) | Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2018-08-15 | Release date: | 2018-10-17 | Last modified: | 2018-11-14 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
|
|