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6MKN

Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin

Summary for 6MKN
Entry DOI10.2210/pdb6mkn/pdb
Descriptor16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (25 entities in total)
Functional Keywords2-thiocytidine, inosine, transfer rna, trna, ribosome, 30s, translation, anticodon
Biological sourceThermus thermophilus HB8
More
Total number of polymer chains23
Total formula weight788484.90
Authors
Cantara, W.A.,DeMirci, H.,Agris, P.F. (deposition date: 2018-09-25, release date: 2019-04-24, Last modification date: 2023-10-11)
Primary citationVangaveti, S.,Cantara, W.A.,Spears, J.L.,DeMirci, H.,Murphy IV, F.V.,Ranganathan, S.V.,Sarachan, K.L.,Agris, P.F.
A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432:913-929, 2020
Cited by
PubMed: 31945376
DOI: 10.1016/j.jmb.2019.12.016
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.46 Å)
Structure validation

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