6MKN
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 16S rRNA | polymer | 1507 | 489191.6 | 1 | GenBank (55771382) | Thermus thermophilus HB8 | |
| 2 | B (B) | 30S ribosomal protein S2 | polymer | 256 | 29317.7 | 1 | UniProt (P80371) Pfam (PF00318) | Thermus thermophilus HB8 | |
| 3 | C (C) | 30S ribosomal protein S3 | polymer | 239 | 26751.1 | 1 | UniProt (P80372) Pfam (PF07650) Pfam (PF00189) | Thermus thermophilus HB8 | |
| 4 | D (D) | 30S ribosomal protein S4 | polymer | 209 | 24373.4 | 1 | UniProt (P80373) Pfam (PF00163) Pfam (PF01479) | Thermus thermophilus HB8 | |
| 5 | E (E) | 30S ribosomal protein S5 | polymer | 162 | 17583.4 | 1 | UniProt (Q5SHQ5) Pfam (PF00333) Pfam (PF03719) | Thermus thermophilus HB8 | |
| 6 | F (F) | 30S ribosomal protein S6 | polymer | 101 | 11988.8 | 1 | UniProt (Q5SLP8) Pfam (PF01250) | Thermus thermophilus HB8 | TS9 |
| 7 | G (G) | 30S ribosomal protein S7 | polymer | 156 | 18051.0 | 1 | UniProt (P17291) Pfam (PF00177) | Thermus thermophilus HB8 | |
| 8 | H (H) | 30S ribosomal protein S8 | polymer | 138 | 15868.6 | 1 | UniProt (P0DOY9) Pfam (PF00410) | Thermus thermophilus HB8 | |
| 9 | I (I) | 30S ribosomal protein S9 | polymer | 128 | 14429.7 | 1 | UniProt (P80374) Pfam (PF00380) | Thermus thermophilus HB8 | |
| 10 | J (J) | 30S ribosomal protein S10 | polymer | 105 | 11955.0 | 1 | UniProt (Q5SHN7) Pfam (PF00338) | Thermus thermophilus HB8 | |
| 11 | K (K) | 30S ribosomal protein S11 | polymer | 129 | 13737.9 | 1 | UniProt (P80376) Pfam (PF00411) | Thermus thermophilus HB8 | |
| 12 | L (L) | 30S ribosomal protein S12 | polymer | 132 | 14637.4 | 1 | UniProt (Q5SHN3) Pfam (PF00164) | Thermus thermophilus HB8 | |
| 13 | M (M) | 30S ribosomal protein S13 | polymer | 126 | 14338.9 | 1 | UniProt (P80377) Pfam (PF00416) | Thermus thermophilus HB8 | |
| 14 | N (N) | 30S ribosomal protein S14 type Z | polymer | 61 | 7158.7 | 1 | UniProt (P0DOY6) Pfam (PF00253) | Thermus thermophilus HB8 | |
| 15 | O (O) | 30S ribosomal protein S15 | polymer | 89 | 10578.4 | 1 | UniProt (Q5SJ76) Pfam (PF00312) | Thermus thermophilus HB8 | |
| 16 | P (P) | 30S ribosomal protein S16 | polymer | 88 | 10410.0 | 1 | UniProt (Q5SJH3) Pfam (PF00886) | Thermus thermophilus HB8 | |
| 17 | Q (Q) | 30S ribosomal protein S17 | polymer | 105 | 12324.7 | 1 | UniProt (P0DOY7) Pfam (PF00366) | Thermus thermophilus HB8 | |
| 18 | R (R) | 30S ribosomal protein S18 | polymer | 88 | 10244.3 | 1 | UniProt (Q5SLQ0) Pfam (PF01084) | Thermus thermophilus HB8 | |
| 19 | S (S) | 30S ribosomal protein S19 | polymer | 93 | 10605.5 | 1 | UniProt (Q5SHP2) Pfam (PF00203) | Thermus thermophilus HB8 | |
| 20 | T (T) | 30S ribosomal protein S20 | polymer | 106 | 11736.1 | 1 | UniProt (P80380) Pfam (PF01649) | Thermus thermophilus HB8 | |
| 21 | U (V) | 30S ribosomal protein Thx | polymer | 27 | 3350.0 | 1 | UniProt (Q5SIH3) Pfam (PF17070) | Thermus thermophilus HB8 | S31 |
| 22 | V (X) | tRNA ASL Escherichia coli Arg2 | polymer | 17 | 5442.3 | 1 | Escherichia coli | ||
| 23 | W (W) | mRNA A-site fragment | polymer | 6 | 1899.2 | 1 | Escherichia coli | ||
| 24 | X (A) | PAROMOMYCIN | non-polymer | 615.6 | 1 | Chemie (PAR) PubChem (165580) PubChem (6602492) PubChem (6713982) PubChem (9961808) PubChem (16757804) PubChem (16760604) PubChem (17757254) PubChem (20849281) PubChem (71191297) PubChem (23789070) PubChem (24096964) PubChem (24867526) PubChem (24867858) PubChem (25104843) PubChem (44120093) PubChem (44251565) PubChem (71188564) PubChem (44186758) PubChem (44663324) PubChem (45358711) PubChem (50989619) PubChem (66932615) PubChem (68032118) PubChem (4689) PubChem (14951) PubChem (24176) PubChem (70878598) PubChem (71751432) PubChem (73707499) PubChem (3040200) PubChem (91867972) PubChem (91972181) PubChem (94469268) PubChem (98048759) PubChem (98048761) PubChem (53486370) PubChem (5702262) PubChem (121292209) PubChem (6603975) PubChem (6604293) PubChem (122537356) PubChem (6710686) PubChem (124226135) PubChem (124464537) PubChem (9809147) PubChem (125040357) PubChem (125040359) PubChem (125121197) PubChem (129009945) PubChem (131841783) PubChem (132275078) PubChem (12313981) PubChem (58160567) PubChem (152952600) PubChem (162873319) PubChem (59361026) PubChem (59800245) PubChem (70793652) PubChem (70793824) PubChem (70795918) PubChem (71068776) PubChem (71072581) PubChem (71072592) PubChem (91151908) PubChem (94469269) PubChem (94469270) PubChem (94469271) PubChem (98048758) PubChem (98048760) PubChem (101739930) PubChem (118213779) PubChem (118705495) PubChem (122691713) PubChem (124226132) PubChem (124226133) PubChem (124226134) PubChem (124464538) PubChem (124761786) PubChem (124761787) PubChem (124761788) PubChem (124761789) PubChem (125040358) PubChem (125040360) PubChem (125121198) PubChem (129014632) PubChem (129014634) PubChem (129014635) PubChem (129313238) PubChem (134771120) PubChem (137404838) PubChem (161153506) PubChem (163199098) PubChem (164850471) PubChem (172091638) PubChem (173719997) | |||
| 25 | AA, AB, AC, BA, BB... (A, E, J) | MAGNESIUM ION | non-polymer | 24.3 | 78 | Chemie (MG) PubChem (888) |
Sequence modifications
A: 5 - 1539 (GenBank: 55771382)
I: 1 - 128 (UniProt: P80374)
Q: 1 - 105 (UniProt: P0DOY7)
R: 1 - 88 (UniProt: Q5SLQ0)
| PDB | External Database | Details |
|---|---|---|
| - | G 132279 | deletion |
| - | G 132309 | deletion |
| - | C 132310 | deletion |
| - | G 132311 | deletion |
| - | A 132312 | deletion |
| - | C 132643 | deletion |
| U 1540 | - | insertion |
| U 1541 | - | insertion |
| U 1542 | - | insertion |
| C 1543 | - | insertion |
| U 1544 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Arg 58 | His 58 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gln 96 | Glu 96 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 60 | Ala 60 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 23 |
| Total formula weight | 785973.5 | |
| Non-Polymers* | Number of molecules | 79 |
| Total formula weight | 2511.4 | |
| All* | Total formula weight | 788484.9 |






