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1HVK	INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE Descriptor: HIV-1 PROTEASE, N-{1-BENZYL-(2S,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE Authors: Bhat, T.N, Hosur, M.V, Baldwin, E.T, Erickson, J.W. Deposit date: 1994-01-26 Release date: 1994-04-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease J.Am.Chem.Soc., 116, 1994
1HVL	INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE Descriptor: HIV-1 PROTEASE, N-{1-BENZYL-(2R,3R)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE Authors: Bhat, T.N, Hosur, M.V, Baldwin, E.T, Erickson, J.W. Deposit date: 1994-01-26 Release date: 1994-04-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease J.Am.Chem.Soc., 116, 1994
1SPD	AMYOTROPHIC LATERAL SCLEROSIS AND STRUCTURAL DEFECTS IN CU,ZN SUPEROXIDE DISMUTASE Descriptor: COPPER (II) ION, SUPEROXIDE DISMUTASE, ZINC ION Authors: Parge, H.E, Tainer, J.A. Deposit date: 1993-07-21 Release date: 1994-04-30 Last modified: 2019-08-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase. Science, 261, 1993
1LYS	X-RAY STRUCTURE OF A MONOCLINIC FORM OF HEN EGG-WHITE LYSOZYME CRYSTALLIZED AT 313K. COMPARISON OF TWO INDEPENDENT MOLECULES Descriptor: HEN EGG WHITE LYSOZYME Authors: Harata, K. Deposit date: 1993-12-03 Release date: 1994-04-30 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.72 Å) Cite: X-ray structure of a monoclinic form of hen egg-white lysozyme crystallized at 313 K. Comparison of two independent molecules. Acta Crystallogr.,Sect.D, 50, 1994
1CRY	APPLICATION OF AN AUTOMATIC MOLECULAR REPLACEMENT PROCEDURE TO CRYSTAL STRUCTURE OF CYTOCHROME C2 FROM RHODOPSEUDOMONAS VIRIDIS Descriptor: CYTOCHROME C2, HEME C Authors: Miki, K, Sogabe, S. Deposit date: 1993-12-27 Release date: 1994-04-30 Last modified: 2021-03-03 Method: X-RAY DIFFRACTION (3 Å) Cite: Application of an automatic molecular-replacement procedure to crystal structure analysis of cytochrome c2 from Rhodopseudomonas viridis. Acta Crystallogr.,Sect.D, 50, 1994
1ESB	DIRECT STRUCTURE OBSERVATION OF AN ACYL-ENZYME INTERMEDIATE IN THE HYDROLYSIS OF AN ESTER SUBSTRATE BY ELASTASE Descriptor: CALCIUM ION, N-[(BENZYLOXY)CARBONYL]-L-ALANINE, PORCINE PANCREATIC ELASTASE, ... Authors: Ding, X, Rasmussen, B, Petsko, G.A, Ringe, D. Deposit date: 1994-02-04 Release date: 1994-04-30 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Direct structural observation of an acyl-enzyme intermediate in the hydrolysis of an ester substrate by elastase. Biochemistry, 33, 1994
1ELC	Analogous inhibitors of elastase do not always bind analogously Descriptor: 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-phenylalaninamide, CALCIUM ION, ELASTASE Authors: Mattos, C, Rasmussen, B, Ding, X, Petsko, G.A, Ringe, D. Deposit date: 1993-12-07 Release date: 1994-04-30 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Analogous inhibitors of elastase do not always bind analogously. Nat.Struct.Biol., 1, 1994
1SPR	BINDING OF A HIGH AFFINITY PHOSPHOTYROSYL PEPTIDE TO THE SRC SH2 DOMAIN: CRYSTAL STRUCTURES OF THE COMPLEXED AND PEPTIDE-FREE FORMS Descriptor: PHOSPHATE ION, SRC TYROSINE KINASE SH2 DOMAIN Authors: Waksman, G, Kuriyan, J. Deposit date: 1993-03-05 Release date: 1994-05-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms. Cell(Cambridge,Mass.), 72, 1993
1SRM	1H AND 15N ASSIGNMENTS AND SECONDARY STRUCTURE OF THE SRC SH3 DOMAIN Descriptor: SRC TYROSINE KINASE SH3 DOMAIN Authors: Yu, H, Rosen, M.K, Shin, T.B, Seidel-Dugan, C, Brugge, J.S, Schreiber, S.L. Deposit date: 1994-03-07 Release date: 1994-05-31 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: 1H and 15N assignments and secondary structure of the Src SH3 domain. FEBS Lett., 324, 1993
1VFB	BOUND WATER MOLECULES AND CONFORMATIONAL STABILIZATION HELP MEDIATE AN ANTIGEN-ANTIBODY ASSOCIATION Descriptor: HEN EGG WHITE LYSOZYME, IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN) Authors: Bhat, T.N, Poljak, R.J. Deposit date: 1993-12-03 Release date: 1994-05-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Bound water molecules and conformational stabilization help mediate an antigen-antibody association. Proc.Natl.Acad.Sci.USA, 91, 1994
2IFF	STRUCTURE OF AN ANTIBODY-LYSOZYME COMPLEX: EFFECT OF A CONSERVATIVE MUTATION Descriptor: HEN EGG WHITE LYSOZYME, IGG1 HYHEL-5 FAB (HEAVY CHAIN), IGG1 HYHEL-5 FAB (LIGHT CHAIN) Authors: Chacko, S, Davies, D.R. Deposit date: 1994-02-03 Release date: 1994-05-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure of an antibody-lysozyme complex unexpected effect of conservative mutation. J.Mol.Biol., 245, 1995
1BRC	RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN Descriptor: AMYLOID BETA-PROTEIN PRECURSOR INHIBITOR DOMAIN (APPI), TRYPSIN Authors: Perona, J.J, Fletterick, R.J. Deposit date: 1992-12-17 Release date: 1994-05-31 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Relocating a negative charge in the binding pocket of trypsin. J.Mol.Biol., 230, 1993
2SPT	DIFFERENCES IN THE METAL ION STRUCTURE BETWEEN SR-AND CA-PROTHROMBIN FRAGMENT 1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTHROMBIN, STRONTIUM ION Authors: Tulinsky, A. Deposit date: 1994-02-01 Release date: 1994-05-31 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Differences in the metal ion structure between Sr- and Ca-prothrombin fragment 1. Biochemistry, 33, 1994
1PCP	SOLUTION STRUCTURE OF A TREFOIL-MOTIF-CONTAINING CELL GROWTH FACTOR, PORCINE SPASMOLYTIC PROTEIN Descriptor: PORCINE SPASMOLYTIC PROTEIN Authors: Carr, M.D, Bauer, C.J, Gradwell, M.J, Feeney, J. Deposit date: 1993-02-04 Release date: 1994-05-31 Last modified: 2017-11-29 Method: SOLUTION NMR Cite: Solution structure of a trefoil-motif-containing cell growth factor, porcine spasmolytic protein. Proc.Natl.Acad.Sci.USA, 91, 1994
1CCF	How an Epidermal Growth Factor (EGF)-Like Domain Binds Calcium-High Resolution NMR Structure of the Calcium Form of the NH2-Terminal EGF-Like Domain in Coagulation Factor X Descriptor: COAGULATION FACTOR X Authors: Selander-Sunnerhagen, M, Ullner, M, Persson, M, Teleman, O, Stenflo, J, Drakenberg, T. Deposit date: 1993-05-19 Release date: 1994-05-31 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: How an epidermal growth factor (EGF)-like domain binds calcium. High resolution NMR structure of the calcium form of the NH2-terminal EGF-like domain in coagulation factor X. J.Biol.Chem., 267, 1992
1PPK	CRYSTALLOGRAPHIC ANALYSIS OF TRANSITION STATE MIMICS BOUND TO PENICILLOPEPSIN: PHOSPHOROUS-CONTAINING PEPTIDE ANALOGUES Descriptor: DIMETHYLFORMAMIDE, N-(3-methylbutanoyl)-L-valyl-N-{(1R)-1-[(R)-(2-ethoxy-2-oxoethyl)(hydroxy)phosphoryl]-3-methylbutyl}-L-valinamide, PENICILLOPEPSIN, ... Authors: Strynadka, N.C.J, James, M.N.G. Deposit date: 1994-01-20 Release date: 1994-05-31 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystallographic analysis of transition-state mimics bound to penicillopepsin: phosphorus-containing peptide analogues. Biochemistry, 31, 1992
1FTZ	NUCLEAR MAGNETIC RESONANCE SOLUTION STRUCTURE OF THE FUSHI TARAZU HOMEODOMAIN FROM DROSOPHILA AND COMPARISON WITH THE ANTENNAPEDIA HOMEODOMAIN Descriptor: FUSHI TARAZU PROTEIN Authors: Qian, Y.Q, Furukubo-Tokunaga, K, Resendez-Perez, D, Muller, M, Gehring, W.J, Wuthrich, K. Deposit date: 1994-01-07 Release date: 1994-05-31 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Nuclear magnetic resonance solution structure of the fushi tarazu homeodomain from Drosophila and comparison with the Antennapedia homeodomain. J.Mol.Biol., 238, 1994
1NRQ	CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), RECEPTOR BASED PEPTIDE D-FPR'S Authors: Tulinsky, A, Mathews, I.I. Deposit date: 1994-01-18 Release date: 1994-05-31 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Biochemistry, 33, 1994
1NRP	CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), RECEPTOR BASED PEPTIDE NR'S Authors: Tulinsky, A, Mathews, I.I. Deposit date: 1994-01-18 Release date: 1994-05-31 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Biochemistry, 33, 1994
1RDH	CRYSTALLOGRAPHIC ANALYSES OF AN ACTIVE HIV-1 RIBONUCLEASE H DOMAIN SHOW STRUCTURAL FEATURES THAT DISTINGUISH IT FROM THE INACTIVE FORM Descriptor: HIV-1 REVERSE TRANSCRIPTASE (RIBONUCLEASE H DOMAIN) Authors: Finzel, B.C, Chattopadhyay, D, Einspahr, H.M. Deposit date: 1993-03-05 Release date: 1994-05-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystallographic analyses of an active HIV-1 ribonuclease H domain show structural features that distinguish it from the inactive form. Acta Crystallogr.,Sect.D, 49, 1993
1HEG	The crystal structures at 2.2 angstroms resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations Descriptor: HIV-1 PROTEASE, methyl N-{(4S,5S)-5-[(L-alanyl-L-alanyl)amino]-4-hydroxy-6-phenylhexanoyl}-L-valyl-L-valinate Authors: Murthy, K, Winborne, E.L, Minnich, M.D, Culp, J.S, Debouck, C. Deposit date: 1992-09-21 Release date: 1994-05-31 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The crystal structures at 2.2-A resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations. J.Biol.Chem., 267, 1992
1HEF	The crystal structures at 2.2 angstroms resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations Descriptor: HIV-1 PROTEASE, SKF 108738 PEPTIDE INHIBITOR Authors: Murthy, K, Winborne, E.L, Minnich, M.D, Culp, J.S, Debouck, C. Deposit date: 1992-09-21 Release date: 1994-05-31 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The crystal structures at 2.2-A resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations. J.Biol.Chem., 267, 1992
1HDA	A NOVEL ALLOSTERIC MECHANISM IN HAEMOGLOBIN. STRUCTURE OF BOVINE DEOXYHAEMOGLOBIN, ABSENCE OF SPECIFIC CHLORIDE-BINDING SITES AND ORIGIN OF THE CHLORIDE-LINKED BOHR EFFECT IN BOVINE AND HUMAN HAEMOGLOBIN Descriptor: HEMOGLOBIN (DEOXY) (ALPHA CHAIN), HEMOGLOBIN (DEOXY) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE Authors: Fermi, G. Deposit date: 1993-05-06 Release date: 1994-05-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A novel allosteric mechanism in haemoglobin. Structure of bovine deoxyhaemoglobin, absence of specific chloride-binding sites and origin of the chloride-linked Bohr effect in bovine and human haemoglobin. J.Mol.Biol., 233, 1993
1NRN	CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), RECEPTOR BASED PEPTIDE NRS Authors: Tulinsky, A, Mathews, I.I. Deposit date: 1994-01-18 Release date: 1994-05-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Biochemistry, 33, 1994
1NRR	Crystallographic structures of Thrombin complexed with Thrombin receptor peptides: Existence of expected and novel binding modes Descriptor: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Proteinase-activated receptor 1, Thrombin heavy chain, ... Authors: Tulinsky, A, Mathews, I.I. Deposit date: 1994-01-18 Release date: 1994-05-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Biochemistry, 33, 1994

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