1D3U
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![BU of 1d3u by Molmil](/molmil-images/mine/1d3u) | TATA-BINDING PROTEIN/TRANSCRIPTION FACTOR (II)B/BRE+TATA-BOX COMPLEX FROM PYROCOCCUS WOESEI | Descriptor: | DNA 23-MER: BRE+TATA-BOX, DNA 24-MER: BRE+TATA-BOX, TATA-BINDING PROTEIN, ... | Authors: | Littlefield, O, Korkhin, Y, Sigler, P.B. | Deposit date: | 1999-10-01 | Release date: | 1999-11-15 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The structural basis for the oriented assembly of a TBP/TFB/promoter complex. Proc.Natl.Acad.Sci.USA, 96, 1999
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8R1L
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![BU of 8r1l by Molmil](/molmil-images/mine/8r1l) | Structure of avian H5N1 influenza A polymerase in complex with human ANP32B. | Descriptor: | Acidic leucine-rich nuclear phosphoprotein 32 family member B, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Carrique, L, Staller, E, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | Deposit date: | 2023-11-02 | Release date: | 2024-05-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation. Nat Commun, 15, 2024
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8R1J
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![BU of 8r1j by Molmil](/molmil-images/mine/8r1j) | Structure of avian H5N1 influenza A polymerase dimer in complex with human ANP32B. | Descriptor: | Acidic leucine-rich nuclear phosphoprotein 32 family member B, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Carrique, L, Staller, E, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | Deposit date: | 2023-11-02 | Release date: | 2024-05-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation. Nat Commun, 15, 2024
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4ROE
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![BU of 4roe by Molmil](/molmil-images/mine/4roe) | Human TFIIB-related factor 2 (Brf2) and TBP bound to RPPH1 promoter | Descriptor: | MAGNESIUM ION, Non-template strand, TATA-box-binding protein, ... | Authors: | Vannini, A, Gouge, J, Satia, K, Guthertz, N. | Deposit date: | 2014-10-28 | Release date: | 2015-12-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2. Cell(Cambridge,Mass.), 163, 2015
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4ROC
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![BU of 4roc by Molmil](/molmil-images/mine/4roc) | Human TFIIB-related factor 2 (Brf2) and TBP bound to U6#2 promoter | Descriptor: | MAGNESIUM ION, Non-template strand, TATA-box-binding protein, ... | Authors: | Vannini, A, Gouge, J, Satia, K, Guthertz, N. | Deposit date: | 2014-10-28 | Release date: | 2015-12-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2. Cell(Cambridge,Mass.), 163, 2015
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4MIW
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![BU of 4miw by Molmil](/molmil-images/mine/4miw) | High-resolution structure of the N-terminal endonuclease domain of the Lassa virus L polymerase | Descriptor: | MAGNESIUM ION, RNA-directed RNA polymerase L | Authors: | Wallat, G.D, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C. | Deposit date: | 2013-09-02 | Release date: | 2014-03-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | High-resolution structure of the N-terminal endonuclease domain of the lassa virus L polymerase in complex with magnesium ions. Plos One, 9, 2014
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6T8H
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![BU of 6t8h by Molmil](/molmil-images/mine/6t8h) | Cryo-EM structure of the DNA-bound PolD-PCNA processive complex from P. abyssi | Descriptor: | DNA polymerase II small subunit, DNA polymerase sliding clamp, DNA primer, ... | Authors: | Madru, C, Raia, P, Hugonneau Beaufet, I, Pehau-Arnaudet, G, England, P, Lindhal, E, Delarue, M, Carroni, M, Sauguet, L. | Deposit date: | 2019-10-24 | Release date: | 2020-03-04 | Last modified: | 2020-04-08 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA. Nat Commun, 11, 2020
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2X1B
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![BU of 2x1b by Molmil](/molmil-images/mine/2x1b) | Structure of RNA15 RRM | Descriptor: | MRNA 3'-END-PROCESSING PROTEIN RNA15, PHOSPHATE ION | Authors: | Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A. | Deposit date: | 2010-01-06 | Release date: | 2010-02-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors. Nucleic Acids Res., 38, 2010
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3FRZ
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![BU of 3frz by Molmil](/molmil-images/mine/3frz) | Crystal Structure of HCV NS5B RNA polymerase in complex with PF868554 | Descriptor: | (6R)-6-cyclopentyl-6-[2-(2,6-diethylpyridin-4-yl)ethyl]-3-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one, BETA-MERCAPTOETHANOL, N-[(benzyloxy)carbonyl]-L-alpha-glutamyl-N-[(1S)-4-oxo-4-phenyl-1-propylbut-2-en-1-yl]-L-phenylalaninamide, ... | Authors: | Parge, H.E. | Deposit date: | 2009-01-08 | Release date: | 2009-03-10 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Discovery of (R)-6-cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a potent and orally available hepatitis C virus polymerase inhibitor. J.Med.Chem., 52, 2009
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4GP7
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![BU of 4gp7 by Molmil](/molmil-images/mine/4gp7) | Polynucleotide kinase | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, MAGNESIUM ION, ... | Authors: | Wang, L.K, Das, U, Smith, P, Shuman, S. | Deposit date: | 2012-08-20 | Release date: | 2012-11-14 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system. Rna, 18, 2012
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4GP6
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![BU of 4gp6 by Molmil](/molmil-images/mine/4gp6) | Polynucleotide kinase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Metallophosphoesterase | Authors: | Wang, L.K, Das, U, Smith, P, Shuman, S. | Deposit date: | 2012-08-20 | Release date: | 2012-11-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system. Rna, 18, 2012
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2NAX
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![BU of 2nax by Molmil](/molmil-images/mine/2nax) | Structure of CCHC zinc finger domain of Pcf11 | Descriptor: | Protein PCF11, ZINC ION | Authors: | Yang, F, Varani, G. | Deposit date: | 2016-01-12 | Release date: | 2016-11-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The C terminus of Pcf11 forms a novel zinc-finger structure that plays an essential role in mRNA 3'-end processing. RNA, 23, 2017
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2Q5E
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![BU of 2q5e by Molmil](/molmil-images/mine/2q5e) | Crystal structure of human carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 | Descriptor: | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2, MAGNESIUM ION | Authors: | Bonanno, J.B, Dickey, M, Bain, K.T, Lau, C, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-05-31 | Release date: | 2007-06-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
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2M17
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![BU of 2m17 by Molmil](/molmil-images/mine/2m17) | |
8R60
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![BU of 8r60 by Molmil](/molmil-images/mine/8r60) | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | Deposit date: | 2023-11-19 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide To Be Published
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8R65
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![BU of 8r65 by Molmil](/molmil-images/mine/8r65) | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | Deposit date: | 2023-11-20 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.23 Å) | Cite: | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains To Be Published
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8GXS
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![BU of 8gxs by Molmil](/molmil-images/mine/8gxs) | PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X. | Deposit date: | 2022-09-21 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
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8GXQ
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![BU of 8gxq by Molmil](/molmil-images/mine/8gxq) | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y. | Deposit date: | 2022-09-21 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (5.04 Å) | Cite: | Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
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8G5Z
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![BU of 8g5z by Molmil](/molmil-images/mine/8g5z) | mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-02-14 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8G6J
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![BU of 8g6j by Molmil](/molmil-images/mine/8g6j) | mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2) | Descriptor: | (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone, (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 1,4-DIAMINOBUTANE, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-02-15 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8G60
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![BU of 8g60 by Molmil](/molmil-images/mine/8g60) | mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-02-14 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8G61
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![BU of 8g61 by Molmil](/molmil-images/mine/8g61) | mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-02-14 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8GLP
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![BU of 8glp by Molmil](/molmil-images/mine/8glp) | mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-03-22 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (1.67 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8G5Y
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![BU of 8g5y by Molmil](/molmil-images/mine/8g5y) | mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-02-14 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.29 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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7Z1L
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![BU of 7z1l by Molmil](/molmil-images/mine/7z1l) | Structure of yeast RNA Polymerase III Pre-Termination Complex (PTC) | Descriptor: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | Authors: | Girbig, M, Mueller, C.W. | Deposit date: | 2022-02-24 | Release date: | 2022-08-31 | Last modified: | 2022-09-21 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals. Cell Rep, 40, 2022
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