PDB: 1406 resultsInfo pagesStatus searchChemie searchBIRD

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4NUJ	Crystal structure of HIV-1 broadly neutralizing antibody PGT152 Descriptor: PGT152 heavy chain, PGT152 light chain Authors: Blattner, C, Wilson, I.A. Deposit date: 2013-12-03 Release date: 2014-05-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.827 Å) Cite: Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers. Immunity, 40, 2014
4NWU	Crystal structure of APE1551, an anti-human NGF Fab with a nine amino acid insertion in CDR H1 Descriptor: APE1551 Ab Fab heavy chain, APE1551 Ab Fab light chain Authors: Verdino, P, Stanfield, R.L, Wilson, I.A. Deposit date: 2013-12-06 Release date: 2014-10-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.602 Å) Cite: Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. J.Biol.Chem., 289, 2014
4NWT	Crystal structure of the anti-human NGF Fab APE1531 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, APE1531 Ab Fab heavy chain, ... Authors: Verdino, P, Stanfield, R.L, Wilson, I.A. Deposit date: 2013-12-06 Release date: 2014-10-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. J.Biol.Chem., 289, 2014
4O5L	Crystal structure of broadly neutralizing antibody F045-092 Descriptor: Fab F045-092 heavy chain, Fab F045-092 light chain, PHOSPHATE ION Authors: Lee, P.S, Wilson, I.A. Deposit date: 2013-12-19 Release date: 2014-04-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5045 Å) Cite: Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nat Commun, 5, 2014
4O5I	Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/361/2011 (H3N2) influenza hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab F045-092 heavy chain, ... Authors: Lee, P.S, Wilson, I.A. Deposit date: 2013-12-19 Release date: 2014-04-16 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (6.501 Å) Cite: Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nat Commun, 5, 2014
4O58	Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/3/1975 (H3N2) influenza hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... Authors: Lee, P.S, Wilson, I.A. Deposit date: 2013-12-19 Release date: 2014-04-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.7501 Å) Cite: Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nat Commun, 5, 2014
4CKD	Model of complex between the E.coli enzyme beta-galactosidase and four single chain Fv antibody domains scFv13R4. Descriptor: BETA-GALACTOSIDASE, SCFV13R4 ANTIBODY FV HEAVY CHAIN, SCFV13R4 ANTIBODY FV LIGHT CHAIN Authors: Vinothkumar, K.R, McMullan, G, Henderson, R. Deposit date: 2014-01-03 Release date: 2014-01-15 Last modified: 2019-10-23 Method: ELECTRON MICROSCOPY (13 Å) Cite: Molecular Mechanism of Antibody-Mediated Activation of Beta-Galactosidase. Structure, 22, 2014
4OB5	Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10 Descriptor: 4E10 antibody germline precursor 7 heavy chain Fv, 4E10 antibody germline precursor 7 light chain Fv, GLYCEROL, ... Authors: Jaffe, J.B, Rupert, P.B. Deposit date: 2014-01-06 Release date: 2014-10-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10. Plos Pathog., 10, 2014
4OCY	Fab for methotrexate (unbound apo) Descriptor: Fab ADD058 Heavy Chain, Fab ADD058 Light Chain Authors: Longenecker, K.L, Judge, R.A, Gayda, S, Manoj, S, Saldana, S, Ruan, Q, Swift, K, Tetin, S. Deposit date: 2014-01-09 Release date: 2014-07-02 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Water channel in the binding site of a high affinity anti-methotrexate antibody. Biochemistry, 53, 2014
4OCX	Fab complex with methotrexate Descriptor: Fab ADD056 Heavy Chain, Fab ADD056 Light Chain, N-(4-{[(2,4-DIAMINOPTERIDIN-1-IUM-6-YL)METHYL](METHYL)AMINO}BENZOYL)-L-GLUTAMIC ACID Authors: Longenecker, K.L, Judge, R.A, Gayda, S, Manoj, S, Saldana, S, Ruan, Q, Swift, K, Tetin, S. Deposit date: 2014-01-09 Release date: 2014-07-02 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Water channel in the binding site of a high affinity anti-methotrexate antibody. Biochemistry, 53, 2014
4ODX	4E10 germline encoded precursor no.7 in complex with epitope scaffold T117 Descriptor: 4E10 epitope scaffold T117, GEP7 Fv heavy chain, GEP7 Fv light chain Authors: Finton, K.A.K. Deposit date: 2014-01-10 Release date: 2014-10-08 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10. Plos Pathog., 10, 2014
4ODB	Crystal structure of the T1L reovirus attachment protein sigma1 in complex with Junctional Adhesion Molecule-A Descriptor: Junctional adhesion molecule A, Outer capsid protein sigma-1 Authors: Stettner, E, Stehle, T. Deposit date: 2014-01-10 Release date: 2015-04-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.2 Å) Cite: The JAM-A binding site is conserved in reovirus sigma1: Structure of the T1L sigma1-JAM-A complex To be Published
4OFI	Crystal Structure of Duf (Kirre) D1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Kin of irre, isoform A, ... Authors: Ozkan, E, Garcia, K.C. Deposit date: 2014-01-14 Release date: 2014-02-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis. Cell(Cambridge,Mass.), 156, 2014
4OFY	Crystal Structure of the Complex of SYG-1 D1-D2 and SYG-2 D1-D4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ETHYL MERCURY ION, ... Authors: Ozkan, E, Garcia, K.C. Deposit date: 2014-01-15 Release date: 2014-02-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis. Cell(Cambridge,Mass.), 156, 2014
4OGY	Crystal structure of Fab DX-2930 in complex with human plasma kallikrein at 2.1 Angstrom resolution Descriptor: 1,2-ETHANEDIOL, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, ... Authors: Edwards, T.E, Clifton, M.C, Abendroth, J, Nixon, A, Ladner, R. Deposit date: 2014-01-16 Release date: 2014-07-09 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J.Biol.Chem., 289, 2014
4OGX	Crystal structure of Fab DX-2930 in complex with human plasma kallikrein at 2.4 Angstrom resolution Descriptor: DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, Plasma kallikrein, ... Authors: Edwards, T.E, Clifton, M.C, Abendroth, J, Nixon, A, Ladner, R. Deposit date: 2014-01-16 Release date: 2014-07-09 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J.Biol.Chem., 289, 2014
4CMM	Structure of human CD47 in complex with human Signal Regulatory Protein (SIRP) alpha v1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUKOCYTE SURFACE ANTIGEN CD47, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 Authors: Hatherley, D, Lea, S.M, Johnson, S, Barclay, A.N. Deposit date: 2014-01-16 Release date: 2014-02-26 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Polymorphisms in the Human Inhibitory Signal-Regulatory Protein Alpha Do not Affect Binding to its Ligand Cd47. J.Biol.Chem., 289, 2014
4OQT	LINGO-1/Li81 Fab complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Li81 Fab, ... Authors: Pepinsky, R.B, Arndt, J.W, Quan, C, Gao, Y, Quintero-Monzon, O, Lee, X, Mi, S. Deposit date: 2014-02-10 Release date: 2014-05-14 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3.23 Å) Cite: Structure of the LINGO-1-Anti-LINGO-1 Li81 Antibody Complex Provides Insights into the Biology of LINGO-1 and the Mechanism of Action of the Antibody Therapy. J.Pharmacol.Exp.Ther., 350, 2014
2MKW	Solution Structure of 6aJl2 and 6aJL2-R24G Amyloidogenics Light Chain Proteins Descriptor: V1-22 protein Authors: Amero, C, Maya-Martinez, R.C, Gil-Rodriguez, P.C. Deposit date: 2014-02-13 Release date: 2014-06-18 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Solution structure of 6aJL2 and 6aJL2-R24G amyloidogenics light chain proteins. Biochem.Biophys.Res.Commun., 456, 2015
4OZF	JR5.1 protein complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DQ alpha 1 chain, ... Authors: Petersen, J, Reid, H.H, Rossjohn, J. Deposit date: 2014-02-15 Release date: 2014-04-16 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.7 Å) Cite: T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014
4OZI	S2 protein complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HLA class II histocompatibility antigen, ... Authors: Petersen, J, Reid, H.H, Rossjohn, J. Deposit date: 2014-02-16 Release date: 2014-04-16 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.2 Å) Cite: T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014
4OZG	D2 protein complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Petersen, J, Reid, H.H, Rossjohn, J. Deposit date: 2014-02-16 Release date: 2014-04-16 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3 Å) Cite: T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014
4OZH	S16 protein complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Gliadin-alpha2 peptide, ... Authors: Petersen, J, Reid, H.H, Rossjohn, J. Deposit date: 2014-02-16 Release date: 2014-04-16 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014
4P2C	Complex of Shiga toxin 2e with a neutralizing single-domain antibody Descriptor: Nanobody 1, Anti-F4+ETEC bacteria VHH variable region, Shiga toxin 2e, ... Authors: Lo, A.W.H, Moonens, K, De Kerpel, M, Brys, L, Pardon, E, Remaut, H, De Greve, H. Deposit date: 2014-03-03 Release date: 2014-07-30 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.818 Å) Cite: The Molecular Mechanism of Shiga Toxin Stx2e Neutralization by a Single-domain Antibody Targeting the Cell Receptor-binding Domain. J.Biol.Chem., 289, 2014
4P3D	MT1-MMP:Fab complex (Form II) Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... Authors: Rozenberg, H, Udi, Y, Sagi, I. Deposit date: 2014-03-07 Release date: 2014-12-17 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.949 Å) Cite: Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody. Structure, 23, 2015

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