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7W6I
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BU of 7w6i by Molmil
The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me1 peptide
Descriptor: Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ...
Authors:Zhao, L, Li, Y, Chen, Y.
Deposit date:2021-12-01
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
7W67
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BU of 7w67 by Molmil
The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me0 peptide
Descriptor: Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ...
Authors:Zhao, L, Li, Y, Chen, Y.
Deposit date:2021-12-01
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.194 Å)
Cite:Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
7W6J
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BU of 7w6j by Molmil
The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me2 peptide
Descriptor: Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ...
Authors:Zhao, L, Li, Y, Chen, Y.
Deposit date:2021-12-01
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
7U5V
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BU of 7u5v by Molmil
Crystal structure of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and Borealin peptide
Descriptor: Borealin, Histone-lysine N-methyltransferase 2A, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:An, S, Cho, U.S, Oh, H, Sha, L, Xu, J, Kim, S, Yang, W, An, W, Dou, Y.
Deposit date:2022-03-02
Release date:2023-09-27
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Non-canonical MLL1 activity regulates centromeric phase separation and genome stability.
Nat.Cell Biol., 25, 2023
7ZEZ
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BU of 7zez by Molmil
Trimolecular complex Cyp33-RRMdelta alpha : MLL1-PHD3 : H3K4me3
Descriptor: Histone H3, Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, MLL cleavage product N320, ...
Authors:Blatter, M, Allain, F, Meylan, C.
Deposit date:2022-03-31
Release date:2022-04-13
Last modified:2023-05-03
Method:SOLUTION NMR
Cite:RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Sci Adv, 9, 2023
2LXT
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BU of 2lxt by Molmil
Allosteric communication in the KIX domain proceeds through dynamic re-packing of the hydrophobic core
Descriptor: CREB-binding protein, Cyclic AMP-responsive element-binding protein 1, Histone-lysine N-methyltransferase MLL
Authors:Bruschweiler, S, Schanda, P, Konrat, R, Tollinger, M.
Deposit date:2012-08-31
Release date:2013-06-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Allosteric communication in the KIX domain proceeds through dynamic repacking of the hydrophobic core.
Acs Chem.Biol., 8, 2013
4JN9
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BU of 4jn9 by Molmil
Crystal structure of the DepH
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DepH, ...
Authors:Li, J, Wang, C, Zhang, Z.M, Zhou, J.H, Cheng, E.
Deposit date:2013-03-14
Release date:2014-04-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis.
Sci Rep, 4, 2014
4JNA
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BU of 4jna by Molmil
Crystal structure of the DepH complex with dimethyl-FK228
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DepH, ...
Authors:Li, J, Wang, C, Zhang, Z.M, Zhou, J.H, Cheng, E.
Deposit date:2013-03-14
Release date:2014-03-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis.
Sci Rep, 4, 2014
2B5Y
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BU of 2b5y by Molmil
Solution Structure of a Thioredoxin-like Protein in the Oxidized Form
Descriptor: YkuV protein
Authors:Zhang, X, Xia, B, Jin, C.
Deposit date:2005-09-29
Release date:2006-01-17
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:The bacillus subtilis YKUV is a thiol-disulfide oxidoreductase revealed by its redox structures and activity
J.Biol.Chem., 281, 2006
2WWU
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BU of 2wwu by Molmil
Crystal structure of the catalytic domain of PHD finger protein 8
Descriptor: ACETATE ION, NICKEL (II) ION, PHD FINGER PROTEIN 8, ...
Authors:Yue, W.W, Hozjan, V, Cooper, C, Tumber, A, Krojer, T, Muniz, J, Allerston, C, Salah, E, McDonough, M.A, von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Schofield, C.J, Kavanagh, K.L, Oppermann, U.
Deposit date:2009-10-29
Release date:2009-11-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase.
FEBS Lett., 584, 2010
2B5X
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BU of 2b5x by Molmil
Solution Structure of a Thioredoxin-like Protein in the Reduced Form
Descriptor: YkuV protein
Authors:Zhang, X, Xia, B, Jin, C.
Deposit date:2005-09-29
Release date:2006-01-17
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The bacillus subtilis YKUV is a thiol-disulfide oxidoreductase revealed by its redox structures and activity
J.Biol.Chem., 281, 2006
2AGH
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BU of 2agh by Molmil
Structural basis for cooperative transcription factor binding to the CBP coactivator
Descriptor: Crebbp protein, Myb proto-oncogene protein, Zinc finger protein HRX
Authors:De Guzman, R.N, Goto, N.K, Dyson, H.J, Wright, P.E.
Deposit date:2005-07-26
Release date:2005-11-22
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Basis for Cooperative Transcription Factor Binding to the CBP Coactivator
J.Mol.Biol., 355, 2006
8U49
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BU of 8u49 by Molmil
The Apo Crystal Structure of BlCel9A from Glycoside Hydrolase Family 9
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
Authors:Araujo, E.A, Polikarpov, I.
Deposit date:2023-09-10
Release date:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular mechanism of cellulose depolymerization by the two-domain BlCel9A enzyme from the glycoside hydrolase family 9.
Carbohydr Polym, 329, 2024
3DXE
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BU of 3dxe by Molmil
Crystal structure of the intracellular domain of human APP (T668A mutant) in complex with Fe65-PTB2
Descriptor: Amyloid beta A4 protein, Amyloid beta A4 protein-binding family B member 1
Authors:Radzimanowski, J, Sinning, I, Wild, K.
Deposit date:2008-07-24
Release date:2008-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
Embo Rep., 9, 2008
8Y0G
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BU of 8y0g by Molmil
Human beta-catenin crystal structure
Descriptor: Catenin beta-1
Authors:Tim, F.
Deposit date:2024-01-22
Release date:2024-03-13
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal protein of human Beta-catenin
To Be Published
8Y14
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BU of 8y14 by Molmil
Beta-catenin Crystal Structure
Descriptor: Catenin beta-1
Authors:Tim, F.
Deposit date:2024-01-23
Release date:2024-03-13
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Beta-catenin Crystal Structure
To Be Published
3OUE
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BU of 3oue by Molmil
Structure of C-terminal hexaheme fragment of GSU1996
Descriptor: Cytochrome c family protein, HEME C, SULFATE ION
Authors:Pokkuluri, P.R, Schiffer, M.
Deposit date:2010-09-14
Release date:2010-12-29
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of a novel dodecaheme cytochrome c from Geobacter sulfurreducens reveals an extended 12nm protein with interacting hemes.
J.Struct.Biol., 174, 2011
8Y0P
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BU of 8y0p by Molmil
Beta-Catenin in complex with peptide 301
Descriptor: B-cell CLL/lymphoma 9 protein, Catenin beta-1, PROLINE
Authors:Tim, F.
Deposit date:2024-01-22
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Beta-Catenin in complex with peptide 301
To Be Published
3DXC
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BU of 3dxc by Molmil
Crystal structure of the intracellular domain of human APP in complex with Fe65-PTB2
Descriptor: Amyloid beta A4 protein, Amyloid beta A4 protein-binding family B member 1
Authors:Radzimanowski, J, Sinning, I, Wild, K.
Deposit date:2008-07-24
Release date:2008-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
Embo Rep., 9, 2008
8Z10
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BU of 8z10 by Molmil
Human beta-catenin crystal structure
Descriptor: Catenin beta-1, PROLINE
Authors:Tim, F.
Deposit date:2024-04-10
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of Beta-catenin
To Be Published
8Z5J
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BU of 8z5j by Molmil
Beta-catenin Crystal Structure
Descriptor: Catenin beta-1
Authors:Tim, F.
Deposit date:2024-04-18
Release date:2024-05-22
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting beta-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells.
J.Med.Chem., 2024
3DXD
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BU of 3dxd by Molmil
Crystal structure of the intracellular domain of human APP (T668E mutant) in complex with Fe65-PTB2
Descriptor: Amyloid beta A4 protein, Amyloid beta A4 protein-binding family B member 1
Authors:Radzimanowski, J, Sinning, I, Wild, K.
Deposit date:2008-07-24
Release date:2008-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
Embo Rep., 9, 2008
8Z61
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BU of 8z61 by Molmil
Human beta-catenin crystal structure
Descriptor: Catenin beta-1
Authors:Tim, F.
Deposit date:2024-04-18
Release date:2024-05-08
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting beta-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells.
J.Med.Chem., 2024
8Z0U
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BU of 8z0u by Molmil
Human beta-catenin crystal structure
Descriptor: Catenin beta-1
Authors:Tim, F.
Deposit date:2024-04-10
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal protein human Beta-catenin
To Be Published
3UVJ
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BU of 3uvj by Molmil
Crystal structure of the catalytic domain of the heterodimeric human soluble guanylate cyclase 1.
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Guanylate cyclase soluble subunit alpha-3, ...
Authors:Allerston, C.K, Berridge, G, Chalk, R, Cooper, C.D.O, Savitsky, P, Vollmar, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, von Delft, F, Gileadi, O, Structural Genomics Consortium (SGC)
Deposit date:2011-11-30
Release date:2011-12-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystal structures of the catalytic domain of human soluble guanylate cyclase.
Plos One, 8, 2013

223532

건을2024-08-07부터공개중

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