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8JWF
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BU of 8jwf by Molmil
Cryo-EM structure of Plasmodium falciparum multidrug resistance protein 1 with H1 helix in complex with MFQ
Descriptor: Mefloquine, Multidrug resistance protein 1
Authors:Li, M, Si, K.
Deposit date:2023-06-29
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JW4
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BU of 8jw4 by Molmil
Cryo-EM structure of Plasmodium falciparum multidrug resistance protein 1 in the apo state without H1 helix
Descriptor: Multidrug resistance protein 1
Authors:Li, M, Si, K.
Deposit date:2023-06-28
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JWI
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BU of 8jwi by Molmil
Cryo-EM structure of the outward-facing Plasmodium falciparum multidrug resistance protein 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance protein 1
Authors:Li, M, Si, K.
Deposit date:2023-06-29
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8TT3
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BU of 8tt3 by Molmil
S. thermodepolymerans KpsM-KpsE in Glycolipid 2 state with rigid body fitted KpsT
Descriptor: (2R,5S,8S)-2,5-dihydroxy-5,10-dioxo-8-[(undecanoyloxy)methyl]-4,6,9-trioxa-5lambda~5~-phosphahenicosan-1-yl 3-deoxy-alpha-L-altro-oct-2-ulopyranosidonic acid, ABC transporter ATP-binding protein, Capsular biosynthesis protein, ...
Authors:Kuklewicz, J, Zimmer, J.
Deposit date:2023-08-12
Release date:2024-04-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular insights into capsular polysaccharide secretion.
Nature, 628, 2024
8JVH
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BU of 8jvh by Molmil
Cryo-EM structure of Plasmodium falciparum multidrug resistance protein 1 in the apo state with H1 helix
Descriptor: Multidrug resistance protein 1
Authors:Li, M, Si, K.
Deposit date:2023-06-28
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8T1P
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BU of 8t1p by Molmil
Heterodimeric ABC transporter BmrCD in the occluded conformation bound to ADPVi: BmrCD_OC-ADPVi
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, ...
Authors:Tang, Q, Mchaourab, H.S.
Deposit date:2023-06-02
Release date:2023-11-15
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8JIA
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BU of 8jia by Molmil
Cryo-EM structure of Mycobacterium tuberculosis ATP bound FtsE(E165Q)X/RipC complex in peptidisc
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ...
Authors:Li, J, Xu, X, Luo, M.
Deposit date:2023-05-26
Release date:2023-10-04
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Regulation of the cell division hydrolase RipC by the FtsEX system in Mycobacterium tuberculosis.
Nat Commun, 14, 2023
8K4B
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BU of 8k4b by Molmil
Cryo-EM structure of nucleotide-bound ComA with ZinC ion
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Competence factor transporting ATP-binding protein/permease ComA, ZINC ION
Authors:Yu, L, Xin, X, Min, L, Feng, H.
Deposit date:2023-07-17
Release date:2023-10-11
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
8JA7
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BU of 8ja7 by Molmil
Cryo-EM structure of Mycobacterium tuberculosis LpqY-SugABC in complex with trehalose
Descriptor: Trehalose import ATP-binding protein SugC, Trehalose transport system permease protein SugA, Trehalose transport system permease protein SugB, ...
Authors:Zhang, B, Liang, J, Rao, Z.
Deposit date:2023-05-05
Release date:2023-09-27
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC.
Proc.Natl.Acad.Sci.USA, 120, 2023
8T3K
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BU of 8t3k by Molmil
Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to ATP: BmrCD_IF-ATP2
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ...
Authors:Tang, Q, Mchaourab, H.
Deposit date:2023-06-07
Release date:2023-11-29
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8VSI
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BU of 8vsi by Molmil
Mechanistic Insights Revealed by YbtPQ in the Occluded State
Descriptor: ABC transporter ATP-binding protein, ADP ORTHOVANADATE, MAGNESIUM ION, ...
Authors:Hu, W, Parkinson, C, Zheng, H.
Deposit date:2024-01-24
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanistic Insights Revealed by YbtPQ in the Occluded State.
Biomolecules, 14, 2024
8K7C
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BU of 8k7c by Molmil
Outward-facing structure of human ABCB6 W546A mutant (ADP/VO4-bound)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family B member 6, MAGNESIUM ION, ...
Authors:Jin, M.S, Lee, S.S, Park, J.G, Jang, E, Choi, S.H, Kim, S, Kim, J.W.
Deposit date:2023-07-26
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state.
Commun Biol, 6, 2023
8K7B
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BU of 8k7b by Molmil
post-occluded structure of human ABCB6 W546A mutant (ADP/VO4-bound)
Descriptor: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ADP ORTHOVANADATE, ATP-binding cassette sub-family B member 6, ...
Authors:Jin, M.S, Lee, S.S, Park, J.G, Jang, E, Choi, S.H, Kim, S, Kim, J.W.
Deposit date:2023-07-26
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state.
Commun Biol, 6, 2023
8K7A
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BU of 8k7a by Molmil
Cryo-EM structure of nucleotide-bound ComA E647Q mutant with Mg2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Transport/processing ATP-binding protein ComA
Authors:Yu, L, Xin, X, Min, L.
Deposit date:2023-07-26
Release date:2023-10-11
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
8Y3X
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BU of 8y3x by Molmil
Cell divisome sPG hydrolysis machinery FtsEX-EnvC
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ...
Authors:Zhang, Z, Dong, H, Chen, Y.
Deposit date:2024-01-29
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structural insight into the septal peptidoglycan hydrolysis machinery of bacterial cell division
To Be Published
8SXA
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BU of 8sxa by Molmil
Inward-facing wide conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc
Descriptor: Multidrug resistance-associated protein 4
Authors:Pourmal, S, Stroud, R.M.
Deposit date:2023-05-20
Release date:2024-01-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SX8
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BU of 8sx8 by Molmil
Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E1 in MSP lipid nanodisc
Descriptor: 7-[(1R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid, Multidrug resistance-associated protein 4
Authors:Pourmal, S, Stroud, R.M.
Deposit date:2023-05-20
Release date:2024-01-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8TUN
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BU of 8tun by Molmil
S. thermodepolymerans KpsM-KpsE in Glycolipid 1 state with rigid body fitted KpsT
Descriptor: (2R,5S,8S)-2,5-dihydroxy-5,10-dioxo-8-[(undecanoyloxy)methyl]-4,6,9-trioxa-5lambda~5~-phosphahenicosan-1-yl 3-deoxy-alpha-L-altro-oct-2-ulopyranosidonic acid, ABC transporter ATP-binding protein, Capsular biosynthesis protein, ...
Authors:Kuklewicz, J, Zimmer, J.
Deposit date:2023-08-16
Release date:2024-04-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular insights into capsular polysaccharide secretion.
Nature, 628, 2024
8X61
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BU of 8x61 by Molmil
Cryo-EM structure of ATP-bound FtsE(E163Q)X
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX
Authors:Zhang, Z.Y, Chen, Y.T.
Deposit date:2023-11-20
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Cryo-EM structure of ATP-bound FtsE(E163Q)X
To Be Published
7QBA
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BU of 7qba by Molmil
CryoEM structure of the ABC transporter NosDFY complexed with nitrous oxide reductase NosZ
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Zipfel, S, Mueller, C, Topitsch, A, Lutz, M, Zhang, L, Einsle, O.
Deposit date:2021-11-18
Release date:2022-08-03
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
8TSW
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BU of 8tsw by Molmil
S. thermodepolymerans KpsMT-KpsE Apo 1
Descriptor: ABC transporter ATP-binding protein, Capsular biosynthesis protein, Transport permease protein
Authors:Kuklewicz, J, Zimmer, J.
Deposit date:2023-08-12
Release date:2024-04-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular insights into capsular polysaccharide secretion.
Nature, 628, 2024
8JXQ
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BU of 8jxq by Molmil
Cryo-EM structure of bilirubin ditaurate (BDT) bound human ABC transporter ABCC2
Descriptor: 2-[3-[5-[(E)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-3-[3-oxidanylidene-3-(2-sulfoethylamino)propyl]-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoylamino]ethanesulfonic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL
Authors:Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
Deposit date:2023-07-01
Release date:2024-01-03
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
8TI1
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BU of 8ti1 by Molmil
Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
Authors:Driggers, C.M, Shyng, S.-L.
Deposit date:2023-07-18
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
Nat Commun, 15, 2024
8TSH
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BU of 8tsh by Molmil
S. thermodepolymerans KpsMT(E151Q)-KpsE in complex with ATP
Descriptor: ABC transporter ATP-binding protein, ADENOSINE-5'-TRIPHOSPHATE, Capsular biosynthesis protein, ...
Authors:Kuklewicz, J, Zimmer, J.
Deposit date:2023-08-11
Release date:2024-04-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular insights into capsular polysaccharide secretion.
Nature, 628, 2024
8WD6
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BU of 8wd6 by Molmil
Cryo-EM structure of the ABCG25
Descriptor: ABC transporter G family member 25
Authors:Xin, J, Yan, K.G.
Deposit date:2023-09-14
Release date:2023-09-27
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Structural insights into AtABCG25, an angiosperm-specific abscisic acid exporter.
Plant Commun., 5, 2024

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