7FDV

Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol

Summary for 7FDV

Entry DOI	10.2210/pdb7fdv/pdb
EMDB information	31547
Descriptor	ATP-binding cassette sub-family G member 1, ADENOSINE-5'-TRIPHOSPHATE, [(E,2S,3R)-2-(hexadecanoylamino)-3-oxidanyl-octadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphate, ... (4 entities in total)
Functional Keywords	human abcg1, cholsterol transporter, atp-bound, cholesterol, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	154535.41
Authors	Xu, D.,Li, Y.Y.,Yang, F.R.,Sun, C.R.,Pan, J.H.,Wang, L.,Chen, Z.P.,Fang, S.C.,Yao, X.B.,Hou, W.T.,Zhou, C.Z.,Chen, Y. (deposition date: 2021-07-18, release date: 2022-06-22, Last modification date: 2022-06-29)
Primary citation	Xu, D.,Li, Y.,Yang, F.,Sun, C.R.,Pan, J.,Wang, L.,Chen, Z.P.,Fang, S.C.,Yao, X.,Hou, W.T.,Zhou, C.Z.,Chen, Y. Structure and transport mechanism of the human cholesterol transporter ABCG1. Cell Rep, 38:110298-110298, 2022 Cited by PubMed: 35081353 DOI: 10.1016/j.celrep.2022.110298 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.26 Å)

Structure validation