7FDV
Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, D) | ATP-binding cassette sub-family G member 1 | polymer | 678 | 75670.8 | 2 | UniProt (P45844) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) | Homo sapiens (human) | ATP-binding cassette transporter 8,White protein homolog |
| 2 | C, G (A, D) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 3 | D, H (A, D) | [(E,2S,3R)-2-(hexadecanoylamino)-3-oxidanyl-octadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphate | non-polymer | 703.0 | 2 | Chemie (HWP) | |||
| 4 | E, F (A, D) | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) |
Sequence modifications
A, D: 1 - 678 (UniProt: P45844)
| PDB | External Database | Details |
|---|---|---|
| Gln 242 | Glu 242 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 151341.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 3193.7 | |
| All* | Total formula weight | 154535.4 |
