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7FDV

Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, DATP-binding cassette sub-family G member 1polymer67875670.82UniProt (P45844)
Pfam (PF00005)
Pfam (PF19055)
Pfam (PF01061)
In PDB
Homo sapiens (human)ATP-binding cassette transporter 8,White protein homolog
2A, DADENOSINE-5'-TRIPHOSPHATEnon-polymer507.22Chemie (ATP)
3A, D[(E,2S,3R)-2-(hexadecanoylamino)-3-oxidanyl-octadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphatenon-polymer703.02Chemie (HWP)
4A, DCHOLESTEROLnon-polymer386.72Chemie (CLR)
Sequence modifications
A, D: 1 - 678 (UniProt: P45844)
PDBExternal DatabaseDetails
Gln 242Glu 242conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight151341.7
Non-Polymers*Number of molecules6
Total formula weight3193.7
All*Total formula weight154535.4
*Water molecules are not included.

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PDB entries from 2024-07-24

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