7E1A

Human bile salt exporter ABCB11 in complex with taurocholate

Summary for 7E1A

Entry DOI	10.2210/pdb7e1a/pdb
EMDB information	30870 30938
Descriptor	Bile salt export pump, TAUROCHOLIC ACID (2 entities in total)
Functional Keywords	abc transporter, liver, membrane protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	147073.09
Authors	Wang, L.,How, W.T.,Chen, Y. (deposition date: 2021-02-01, release date: 2022-02-09, Last modification date: 2024-06-05)
Primary citation	Wang, L.,Hou, W.T.,Wang, J.,Xu, D.,Guo, C.,Sun, L.,Ruan, K.,Zhou, C.Z.,Chen, Y. Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets. Cell Res., 32:501-504, 2022 Cited by PubMed: 35043010 DOI: 10.1038/s41422-021-00611-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.66 Å)

Structure validation