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7WLR
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BU of 7wlr by Molmil
Cryo-EM structure of the nucleosome containing Komagataella pastoris histones
Descriptor: DNA (145-MER), Histone H2A, Histone H2B, ...
Authors:Fukushima, Y, Hatazawa, S, Hirai, S, Kujirai, T, Takizawa, Y, Kurumizaka, H.
Deposit date:2022-01-13
Release date:2022-07-13
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural and biochemical analyses of the nucleosome containing Komagataella pastoris histones.
J.Biochem., 172, 2022
2NPI
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BU of 2npi by Molmil
Clp1-ATP-Pcf11 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein CLP1, ...
Authors:Noble, C.G, Beuth, B, Taylor, I.A.
Deposit date:2006-10-27
Release date:2006-12-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
Nucleic Acids Res., 35, 2007
6EKM
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BU of 6ekm by Molmil
Crystal structure of mammalian Rev7 in complex with human Rev3 second binding site
Descriptor: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Huber, F, Tropia, L, Emamzadah, S, Halazonetis, T.
Deposit date:2017-09-26
Release date:2018-10-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Crystal structure of mammalian Rev7 in complex with human Rev3
To Be Published
3PY3
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BU of 3py3 by Molmil
Crystal structure of phosphorylated p38alpha MAP kinase
Descriptor: Mitogen-activated protein kinase 14
Authors:Zhang, Y.Y, Wu, J.W, Wang, Z.X.
Deposit date:2010-12-11
Release date:2011-03-16
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mitogen-activated Protein Kinase (MAPK) Phosphatase 3-mediated Cross-talk between MAPKs ERK2 and p38{alpha}.
J.Biol.Chem., 286, 2011
2C9O
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BU of 2c9o by Molmil
3D Structure of the human RuvB-like helicase RuvBL1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RUVB-LIKE 1
Authors:Matias, P.M, Gorynia, S, Donner, P, Carrondo, M.A.
Deposit date:2005-12-14
Release date:2006-10-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the human AAA+ protein RuvBL1.
J. Biol. Chem., 281, 2006
1UET
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BU of 1uet by Molmil
Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure
Descriptor: ACETATE ION, CALCIUM ION, MAGNESIUM ION, ...
Authors:Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-21
Release date:2003-12-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure.
Embo J., 22, 2003
8SNB
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BU of 8snb by Molmil
atomic model of sea urchin sperm doublet microtubule (48-nm periodicity)
Descriptor: ATP6V1FNB, C20Orf85, C4orf45, ...
Authors:Zeng, J, Zhang, R.
Deposit date:2023-04-26
Release date:2023-06-28
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural specializations of the sperm tail.
Cell, 186, 2023
1UEU
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BU of 1ueu by Molmil
Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure
Descriptor: ACETATE ION, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-21
Release date:2003-12-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure.
Embo J., 22, 2003
3OXL
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BU of 3oxl by Molmil
Human lysine methyltransferase Smyd3 in complex with AdoHcy (Form II)
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, SET and MYND domain-containing protein 3, ZINC ION
Authors:Xu, S, Wu, J, Sun, B, Zhong, C, Ding, J.
Deposit date:2010-09-21
Release date:2011-02-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding
Nucleic Acids Res., 39, 2011
7UQK
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BU of 7uqk by Molmil
Cryo-EM structure of the S. cerevisiae chromatin remodeler Yta7 hexamer bound to ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase histone chaperone YTA7
Authors:Wang, F, Feng, X, Li, H.
Deposit date:2022-04-19
Release date:2023-02-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The Saccharomyces cerevisiae Yta7 ATPase hexamer contains a unique bromodomain tier that functions in nucleosome disassembly.
J.Biol.Chem., 299, 2022
7UQI
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BU of 7uqi by Molmil
Cryo-EM structure of the S. cerevisiae chromatin remodeler Yta7 hexamer bound to ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase histone chaperone YTA7
Authors:Wang, F, Feng, X, Li, H.
Deposit date:2022-04-19
Release date:2023-02-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The Saccharomyces cerevisiae Yta7 ATPase hexamer contains a unique bromodomain tier that functions in nucleosome disassembly.
J.Biol.Chem., 299, 2022
3O96
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BU of 3o96 by Molmil
Crystal Structure of Human AKT1 with an Allosteric Inhibitor
Descriptor: 1-(1-(4-(7-phenyl-1H-imidazo[4,5-g]quinoxalin-6-yl)benzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one, RAC-alpha serine/threonine-protein kinase
Authors:Voegtli, W.C, Wu, W.-I, Lord-Ondash, H.A, Dizon, F.P, Vigers, G.P.A, Brandhuber, B.J.
Deposit date:2010-08-03
Release date:2010-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of human AKT1 with an allosteric inhibitor reveals a new mode of kinase inhibition.
Plos One, 5, 2010
2YOL
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BU of 2yol by Molmil
West Nile Virus NS2B-NS3 protease in complex with 3,4- dichlorophenylacetyl-Lys-Lys-GCMA
Descriptor: (S)-6-amino-N-((S)-6-amino-1-(((1r,4S)-4-guanidinocyclohexyl)methylamino)-1-oxohexan-2-yl)-2-(2-(3,4-dichlorophenyl)acetamido)hexanamide, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Hammamy, M.Z, Haase, C, Hammami, M, Hilgenfeld, R, Steinmetzer, T.
Deposit date:2012-10-25
Release date:2013-03-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Development and Characterization of New Peptidomimetic Inhibitors of the West Nile Virus Ns2B-Ns3 Protease.
Chemmedchem, 8, 2013
3P57
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BU of 3p57 by Molmil
Crystal structure of the p300 TAZ2 domain bound to MEF2 on DNA
Descriptor: DNA (5'-D(*A*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3'), Histone acetyltransferase p300, ...
Authors:He, J, Ye, J, Riquelme, C, Liu, J.O.
Deposit date:2010-10-08
Release date:2011-08-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1921 Å)
Cite:Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly.
Nucleic Acids Res., 39, 2011
5VFT
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BU of 5vft by Molmil
Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ...
Authors:Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y.
Deposit date:2017-04-09
Release date:2018-07-18
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5BWM
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BU of 5bwm by Molmil
The complex structure of C3cer exoenzyme and GDP bound RhoA (NADH-bound state)
Descriptor: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADP-ribosyltransferase, ...
Authors:Toda, A, Tsurumura, T, Yoshida, T, Tsuge, H.
Deposit date:2015-06-08
Release date:2015-06-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure.
J.Biol.Chem., 290, 2015
1UEV
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BU of 1uev by Molmil
Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-21
Release date:2003-12-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure.
Embo J., 22, 2003
1A2B
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BU of 1a2b by Molmil
HUMAN RHOA COMPLEXED WITH GTP ANALOGUE
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA
Authors:Ihara, K, Muraguchi, S, Kato, M, Shimizu, T, Shirakawa, M, Kuroda, S, Kaibuchi, K, Hakoshima, T.
Deposit date:1997-12-26
Release date:1998-06-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue.
J.Biol.Chem., 273, 1998
4FU3
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BU of 4fu3 by Molmil
CID of human RPRD1B
Descriptor: CHLORIDE ION, Regulation of nuclear pre-mRNA domain-containing protein 1B, UNKNOWN ATOM OR ION
Authors:Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC)
Deposit date:2012-06-28
Release date:2012-08-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:CID of human RPRD1B
TO BE PUBLISHED
5HRK
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BU of 5hrk by Molmil
The crystal structure of AsfvPolX(H115F mutant): 1nt-gap(P) DNA2:dGTP ternary complex
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*TP*CP*TP*AP*TP*GP*TP*GP*TP*AP*CP*TP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*AP*GP*TP*AP*CP*A)-3'), ...
Authors:Chen, Y.Q, Zhang, J, Gan, J.H.
Deposit date:2016-01-23
Release date:2017-01-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1
To Be Published
5HRF
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BU of 5hrf by Molmil
The crystal structure of AsfvPolX: DNA5: dGTP ternary complex
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*GP*AP*TP*CP*CP*T*)-3'), DNA polymerase beta-like protein, ...
Authors:Chen, Y.Q, Zhang, J, Gan, J.H.
Deposit date:2016-01-23
Release date:2017-01-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1
To Be Published
5HRH
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BU of 5hrh by Molmil
The crystal structure of AsfvPolX(H115F/R127A mutant): 1nt-gap(P) DNA2:dGTP ternary complex
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*TP*CP*TP*AP*TP*GP*TP*GP*TP*AP*CP*TP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*AP*GP*TP*AP*CP*A*)-3'), ...
Authors:Chen, Y.Q, Zhang, J, Gan, J.H.
Deposit date:2016-01-23
Release date:2017-01-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1
To Be Published
5HRL
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BU of 5hrl by Molmil
The crystal structure of AsfvPolX: 1nt-gap(P) DNA2: dGTP ternary complex.
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*TP*CP*TP*AP*TP*GP*TP*GP*TP*AP*CP*TP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*AP*GP*TP*AP*CP*A)-3'), ...
Authors:Chen, Y.Q, Zhang, J, Gan, J.H.
Deposit date:2016-01-23
Release date:2017-01-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1
To Be Published
4IL1
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BU of 4il1 by Molmil
Crystal Structure of the Rat Calcineurin
Descriptor: CALCIUM ION, Calmodulin, Calcineurin subunit B type 1, ...
Authors:Ye, Q, Faucher, F, Jia, Z.
Deposit date:2012-12-28
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of calcineurin activation by calmodulin.
Cell Signal, 25, 2013
4I5H
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BU of 4i5h by Molmil
Crystal Structure of a Double Mutant Rat Erk2 Complexed With a Type II Quinazoline Inhibitor
Descriptor: Mitogen-activated protein kinase 1, N-{3-[2-(cyclopropylamino)quinazolin-6-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide
Authors:Hari, S.B, Maly, D.J, Merritt, E.A.
Deposit date:2012-11-28
Release date:2013-07-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sequence determinants of a specific inactive protein kinase conformation.
Chem.Biol., 20, 2013

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