8PIF
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![BU of 8pif by Molmil](/molmil-images/mine/8pif) | Fragment 12 in complex with KLHDC2 | Descriptor: | 1,2-ETHANEDIOL, 2-(furan-3-yl)ethanoic acid, Kelch domain-containing protein 2 | Authors: | Boettcher, J, Mayer, M. | Deposit date: | 2023-06-21 | Release date: | 2023-07-12 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.782 Å) | Cite: | KLHDC2 - The Next Level To Be Published
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2UVK
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![BU of 2uvk by Molmil](/molmil-images/mine/2uvk) | Structure of YjhT | Descriptor: | YJHT | Authors: | Muller, A, Severi, E, Wilson, K.S, Thomas, G.H. | Deposit date: | 2007-03-12 | Release date: | 2007-12-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Sialic Acid Mutarotation is Catalyzed by the Escherichia Coli Beta-Propeller Protein Yjht. J.Biol.Chem., 283, 2008
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8UXS
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![BU of 8uxs by Molmil](/molmil-images/mine/8uxs) | |
6DO4
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![BU of 6do4 by Molmil](/molmil-images/mine/6do4) | KLHDC2 ubiquitin ligase in complex with SelS C-end degron | Descriptor: | Kelch domain-containing protein 2, SELS C-END DEGRON | Authors: | Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. | Deposit date: | 2018-06-08 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase. Mol. Cell, 72, 2018
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6DO3
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![BU of 6do3 by Molmil](/molmil-images/mine/6do3) | KLHDC2 ubiquitin ligase in complex with SelK C-end degron | Descriptor: | Kelch domain-containing protein 2, SelK C-end Degron | Authors: | Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. | Deposit date: | 2018-06-08 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.165 Å) | Cite: | Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase. Mol. Cell, 72, 2018
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6DO5
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![BU of 6do5 by Molmil](/molmil-images/mine/6do5) | KLHDC2 ubiquitin ligase in complex with USP1 C-end degron | Descriptor: | Kelch domain-containing protein 2, USP1 C-END DEGRON | Authors: | Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. | Deposit date: | 2018-06-08 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase. Mol. Cell, 72, 2018
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8SGE
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![BU of 8sge by Molmil](/molmil-images/mine/8sge) | KLHDC2 Kelch Domain with ligand KDRLKZ-1 | Descriptor: | GLYCEROL, Kelch domain-containing protein 2, [(5P)-5-{3-[(2R)-butan-2-yl]-7-[(2-methoxyethoxy)carbonyl]-2-oxo-5,6,7,8-tetrahydro-1,7-naphthyridin-1(2H)-yl}-2-oxopyridin-1(2H)-yl]acetic acid | Authors: | Digianantonio, K.M, Bekes, M, Langley, D.R, Zimmerman, K. | Deposit date: | 2023-04-12 | Release date: | 2024-01-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.509 Å) | Cite: | Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat.Struct.Mol.Biol., 31, 2024
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8SGF
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![BU of 8sgf by Molmil](/molmil-images/mine/8sgf) | KLHDC2 Kelch Domain with KLHDC2 c-terminal peptide bound | Descriptor: | GLYCEROL, HIS-SER-VAL-ASN-GLN-ARG-PHE-GLY-SER-ASN-ASN-THR-SER-GLY-SER, Kelch domain-containing protein 2 | Authors: | Digianantonio, K.M, Bekes, M, Langley, D.R, Zimmerman, K. | Deposit date: | 2023-04-12 | Release date: | 2024-01-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.418 Å) | Cite: | Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat.Struct.Mol.Biol., 31, 2024
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8EBM
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![BU of 8ebm by Molmil](/molmil-images/mine/8ebm) | |
8EBL
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![BU of 8ebl by Molmil](/molmil-images/mine/8ebl) | |
6ZYW
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![BU of 6zyw by Molmil](/molmil-images/mine/6zyw) | Outer Dynein Arm-Shulin complex - overall structure (Tetrahymena thermophila) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ... | Authors: | Mali, G.R, Abid Ali, F, Lau, C.K, Carter, A.P. | Deposit date: | 2020-08-03 | Release date: | 2021-01-20 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (8.78 Å) | Cite: | Shulin packages axonemal outer dynein arms for ciliary targeting. Science, 371, 2021
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8GLV
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![BU of 8glv by Molmil](/molmil-images/mine/8glv) | |
8BWY
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![BU of 8bwy by Molmil](/molmil-images/mine/8bwy) | In situ outer dynein arm from Chlamydomonas reinhardtii in a pre-power stroke state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Calmodulin, ... | Authors: | Zimmermann, N.E.L, Noga, A, Obbineni, J.M, Ishikawa, T. | Deposit date: | 2022-12-07 | Release date: | 2023-05-10 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (38 Å) | Cite: | ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography. Embo J., 42, 2023
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8BX8
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![BU of 8bx8 by Molmil](/molmil-images/mine/8bx8) | In situ outer dynein arm from Chlamydomonas reinhardtii in the post-power stroke state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ... | Authors: | Zimmermann, N.E.L, Noga, A, Obbineni, J.M, Ishikawa, T. | Deposit date: | 2022-12-08 | Release date: | 2023-05-10 | Last modified: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (30.299999 Å) | Cite: | ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography. Embo J., 42, 2023
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8SH2
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![BU of 8sh2 by Molmil](/molmil-images/mine/8sh2) | KLHDC2 in complex with EloB and EloC | Descriptor: | Elongin-B, Elongin-C, Kelch domain-containing protein 2 | Authors: | Digianantonio, K.M, Bekes, M. | Deposit date: | 2023-04-13 | Release date: | 2024-01-03 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.74 Å) | Cite: | Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat.Struct.Mol.Biol., 31, 2024
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8EBN
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![BU of 8ebn by Molmil](/molmil-images/mine/8ebn) | Structure of KLHDC2-EloB/C tetrameric assembly | Descriptor: | Elongin-B, Elongin-C, Kelch domain-containing protein 2 | Authors: | Scott, D.C, Schulman, B.A. | Deposit date: | 2022-08-31 | Release date: | 2023-02-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity. Mol.Cell, 83, 2023
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7KEK
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![BU of 7kek by Molmil](/molmil-images/mine/7kek) | Structure of the free outer-arm dynein in pre-parallel state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein alpha heavy chain, ... | Authors: | Rao, Q, Zhang, K. | Deposit date: | 2020-10-11 | Release date: | 2021-09-29 | Last modified: | 2021-10-20 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism. Nat.Struct.Mol.Biol., 28, 2021
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7KZM
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![BU of 7kzm by Molmil](/molmil-images/mine/7kzm) | Outer dynein arm bound to doublet microtubules from C. reinhardtii | Descriptor: | DC1, DC2, Dynein 11 kDa light chain, ... | Authors: | Walton, T, Wu, H, Brown, A.B. | Deposit date: | 2020-12-10 | Release date: | 2021-01-20 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Structure of a microtubule-bound axonemal dynein. Nat Commun, 12, 2021
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7MOQ
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![BU of 7moq by Molmil](/molmil-images/mine/7moq) | The structure of the Tetrahymena thermophila outer dynein arm on doublet microtubule | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Docking complex 1 protein, ... | Authors: | Kubo, S, Yang, S.K, Ichikawa, M, Bui, K.H. | Deposit date: | 2021-05-03 | Release date: | 2021-07-14 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Remodeling and activation mechanisms of outer arm dyneins revealed by cryo-EM. Embo Rep., 22, 2021
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7KZN
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![BU of 7kzn by Molmil](/molmil-images/mine/7kzn) | Outer dynein arm core subcomplex from C. reinhardtii | Descriptor: | DC1, DC2, Dynein 11 kDa light chain, ... | Authors: | Walton, T, Wu, H, Brown, A.B. | Deposit date: | 2020-12-10 | Release date: | 2021-01-20 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of a microtubule-bound axonemal dynein. Nat Commun, 12, 2021
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