6DO3

KLHDC2 ubiquitin ligase in complex with SelK C-end degron

Summary for 6DO3

Entry DOI	10.2210/pdb6do3/pdb
Descriptor	Kelch domain-containing protein 2, SelK C-end Degron (3 entities in total)
Functional Keywords	kelch repeat, beta-propeller, degron, complex, substrate receptor, e3, ubiquitin ligase, ligase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	83953.76
Authors	Rusnac, D.V.,Lin, H.C.,Yen, H.C.S.,Zheng, N. (deposition date: 2018-06-08, release date: 2018-12-19, Last modification date: 2023-10-11)
Primary citation	Rusnac, D.V.,Lin, H.C.,Canzani, D.,Tien, K.X.,Hinds, T.R.,Tsue, A.F.,Bush, M.F.,Yen, H.S.,Zheng, N. Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase. Mol. Cell, 72:813-822.e4, 2018 Cited by PubMed: 30526872 DOI: 10.1016/j.molcel.2018.10.021 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.165 Å)

Structure validation