8UXS

KLHDC2 ubiquitin ligase in complex with a novel small-molecule

Summary for 8UXS

• Entry DOI: 10.2210/pdb8uxs/pdb
• Descriptor: Kelch domain-containing protein 2, {4-[(2-{[(4-tert-butylphenyl)methyl]sulfanyl}acetamido)methyl]-1H-1,2,3-triazol-1-yl}acetic acid (3 entities in total)
• Functional Keywords: kelch repeat, beta-propeller, small-molecule, complex, substrate receptor, e3, ubiquitin ligase, ligase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 78748.32

Authors

Rusnac, D.V.,Zheng, N. (deposition date: 2023-11-10, release date: 2024-07-10)

• Primary citation: Rusnac, D.V.,Zhou, G.,Canzani, D.,Bush, M.F.,DiMaio, F.,Zheng, N.; KLHDC2 ubiquitin ligase in complex with a novel small-molecule; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)