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2WFT
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BU of 2wft by Molmil
Crystal structure of the human HIP ectodomain
分子名称: CHLORIDE ION, HEDGEHOG-INTERACTING PROTEIN, SODIUM ION
著者Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C.
登録日2009-04-15
公開日2009-06-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
3HO4
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BU of 3ho4 by Molmil
Crystal structure of Hedgehog-interacting protein (HHIP)
分子名称: Hedgehog-interacting protein
著者Hymowitz, S.G, Bosanac, I.
登録日2009-06-01
公開日2009-06-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.
Nat.Struct.Mol.Biol., 16, 2009
3HO3
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BU of 3ho3 by Molmil
Crystal structure of Hedgehog-interacting protein (HHIP)
分子名称: Hedgehog-interacting protein
著者Bosanac, I, Hymowitz, S.G.
登録日2009-06-01
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.
Nat.Struct.Mol.Biol., 16, 2009
7PGM
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HHIP-C in complex with heparin
分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-3)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Hedgehog-interacting protein
著者Griffiths, S.C, Schwab, R.A, El Omari, K, Bishop, B, Iverson, E.J, Malinuskas, T, Dubey, R, Qian, M, Covey, D.F, Gilbert, R.J.C, Rohatgi, R, Siebold, C.
登録日2021-08-14
公開日2021-12-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling.
Nat Commun, 12, 2021
7PGN
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HHP-C in complex with glycosaminoglycan mimic SOS
分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
著者Griffiths, S.C, Schwab, R.A, El Omari, K, Bishop, B, Iverson, E.J, Malinuskas, T, Dubey, R, Qian, M, Covey, D.F, Gilbert, R.J.C, Rohatgi, R, Siebold, C.
登録日2021-08-14
公開日2021-12-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling.
Nat Commun, 12, 2021
1U8C
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BU of 1u8c by Molmil
A novel adaptation of the integrin PSI domain revealed from its crystal structure
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Xiong, J.P, Stehle, T, Goodman, S.L, Arnaout, M.A.
登録日2004-08-05
公開日2004-12-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A novel adaptation of the integrin PSI domain revealed from its crystal structure.
J.Biol.Chem., 279, 2004
8Y6B
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BU of 8y6b by Molmil
Structure of human LGI1-ADAM22 complex in space group P212121
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 22, ...
著者Liu, H, Xu, F.
登録日2024-02-02
公開日2024-02-14
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Structure of human LGI1-ADAM22 complex in space group P212121
To Be Published
4UM8
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BU of 4um8 by Molmil
Crystal structure of alpha V beta 6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, ...
著者Dong, X, Springer, T.A.
登録日2014-05-15
公開日2014-11-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.852 Å)
主引用文献Structural Determinants of Integrin Beta-Subunit Specificity for Latent Tgf-Beta
Nat.Struct.Mol.Biol., 21, 2014
7LA4
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BU of 7la4 by Molmil
Integrin AlphaIIbBeta3-PT25-2 Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Bush, M.W, Walz, T, Coller, B, Filizola, M, Spasic, A, Nesic, D, Li, J.
登録日2021-01-05
公開日2022-01-12
最終更新日2022-07-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Electron microscopy shows that binding of monoclonal antibody PT25-2 primes integrin alpha IIb beta 3 for ligand binding.
Blood Adv, 5, 2021
4Z80
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BU of 4z80 by Molmil
Crystal structure of Toxoplasma gondii AMA4 DI-DII-EGF1 in complex with a 33 aa TgRON2L1 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytoadherence-linked asexual protein, EGF family domain-containing protein, ...
著者Parker, M.L, Boulanger, M.J.
登録日2015-04-08
公開日2015-12-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
4Z81
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BU of 4z81 by Molmil
Crystal structure of AMA4 DI-DII-EGF1 from Toxoplasma gondii
分子名称: EGF family domain-containing protein, GLYCEROL
著者Parker, M.L, Boulanger, M.J.
登録日2015-04-08
公開日2015-12-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
5Y31
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BU of 5y31 by Molmil
Crystal structure of human LGI1-ADAM22 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 22, ...
著者Yamagata, A, Fukai, S.
登録日2017-07-27
公開日2018-05-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (7.125 Å)
主引用文献Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.
Nat Commun, 9, 2018
5Y2Z
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BU of 5y2z by Molmil
Crystal structure of human LGI1 EPTP-ADAM22 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yamagata, A, Fukai, S.
登録日2017-07-27
公開日2018-05-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.
Nat Commun, 9, 2018
8T2V
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BU of 8t2v by Molmil
Cryo-EM Structures of Full-length Integrin alphaIIbbeta3 in Native Lipids
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
登録日2023-06-06
公開日2023-07-26
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of full-length integrin alpha IIb beta 3 in native lipids.
Nat Commun, 14, 2023
8T2U
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BU of 8t2u by Molmil
Cryo-EM Structures of Full-length Integrin alphaIIbbeta3 in Native Lipids complexed with Eptifibatide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
登録日2023-06-06
公開日2023-07-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structures of full-length integrin alpha IIb beta 3 in native lipids.
Nat Commun, 14, 2023
3FCS
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BU of 3fcs by Molmil
Structure of complete ectodomain of integrin aIIBb3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Zhu, J, Luo, B.-H, Xiao, T, Zhang, C, Nishida, N, Springer, T.A.
登録日2008-11-22
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces.
Mol.Cell, 32, 2008
3G5C
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BU of 3g5c by Molmil
Structural and biochemical studies on the ectodomain of human ADAM22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADAM 22, CALCIUM ION
著者Liu, H, Shim, A, Chen, X, He, X.
登録日2009-02-04
公開日2009-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural and biochemical studies on the ectodomain of human ADAM22
J.Biol.Chem., 2009
4CAK
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BU of 4cak by Molmil
Three-dimensional reconstruction of intact human integrin alphaIIbbeta3 in a phospholipid bilayer nanodisc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-IIb, ...
著者Choi, W.S, Rice, W.J, Stokes, D.L, Coller, B.S.
登録日2013-10-08
公開日2013-10-30
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (20.5 Å)
主引用文献Three-Dimensional Reconstruction of Intact Human Integrin Alphaiibbeta3; New Implications for Activation-Dependent Ligand Binding.
Blood, 122, 2013
1JV2
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BU of 1jv2 by Molmil
CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN ALPHAVBETA3
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Xiong, J.P, Stehle, T, Diefenbach, B, Zhang, R, Dunker, R, Scott, D, Joachimiak, A, Goodman, S.L, Arnaout, M.A.
登録日2001-08-28
公開日2001-10-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of the extracellular segment of integrin alpha Vbeta3.
Science, 294, 2001
1L5G
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BU of 1l5g by Molmil
CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN AVB3 IN COMPLEX WITH AN ARG-GLY-ASP LIGAND
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Xiong, J.-P, Stehle, T, Zhang, R, Joachimiak, A, Frech, M, Goodman, S.L, Arnaout, M.A.
登録日2002-03-06
公開日2002-04-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand.
Science, 296, 2002
1M1X
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BU of 1m1x by Molmil
CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN ALPHA VBETA3 BOUND TO MN2+
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Xiong, J.-P, Stehle, T, Zhang, R, Joachimiak, A, Frech, M, Goodman, S.L, Arnaout, M.A.
登録日2002-06-20
公開日2002-08-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand.
Science, 296, 2002
4G1E
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BU of 4g1e by Molmil
Crystal structure of integrin alpha V beta 3 with coil-coiled tag.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Dong, X, Mi, L, Zhu, J, Wang, W, Luo, B, Springer, T.A.
登録日2012-07-10
公開日2012-12-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献AlphaV Beta3 Integrin Crystal Structures and their Functional Implications
Biochemistry, 51, 2012
4G1M
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BU of 4g1m by Molmil
Re-refinement of alpha V beta 3 structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Springer, T.A, Mi, L, Zhu, J.
登録日2012-07-10
公開日2012-12-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Alpha V Beta 3 Integrin Crystal Structures and their Functional Implications
Biochemistry, 51, 2012
2WFX
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BU of 2wfx by Molmil
Crystal structure of the complex between human hedgehog-interacting protein HIP and Sonic Hedgehog in the presence of calcium
分子名称: CALCIUM ION, HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, ...
著者Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C.
登録日2009-04-15
公開日2009-06-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
2WG3
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Crystal structure of the complex between human hedgehog-interacting protein HIP and desert hedgehog without calcium
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DESERT HEDGEHOG PROTEIN N-PRODUCT, ...
著者Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C.
登録日2009-04-15
公開日2009-06-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009

 

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