4CAK

Three-dimensional reconstruction of intact human integrin alphaIIbbeta3 in a phospholipid bilayer nanodisc

Summary for 4CAK

• Entry DOI: 10.2210/pdb4cak/pdb
• EMDB information: 2281
• Descriptor: Integrin alpha-IIb, Integrin beta-3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: cell adhesion, integrin, single particle reconstruction
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 184314.93

Authors

Choi, W.S.,Rice, W.J.,Stokes, D.L.,Coller, B.S. (deposition date: 2013-10-08, release date: 2013-10-30, Last modification date: 2020-07-29)

• Primary citation: Choi, W.S.,Rice, W.J.,Stokes, D.L.,Coller, B.S.; Three-Dimensional Reconstruction of Intact Human Integrin Alphaiibbeta3; New Implications for Activation-Dependent Ligand Binding.; Blood, 122:4165-, 2013; PubMed: 24136164; DOI: 10.1182/BLOOD-2013-04-499194

Experimental method

ELECTRON MICROSCOPY (20.5 Å)