2GSL
| X-Ray Crystal Structure of Protein FN1578 from Fusobacterium nucleatum. Northeast Structural Genomics Consortium Target NR1. | 分子名称: | Hypothetical protein, MAGNESIUM ION | 著者 | Forouhar, F, Su, M, Jayaraman, S, Conover, K, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-04-26 | 公開日 | 2006-05-09 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of the Hypothetical Protein (FN1578) from Fusobacterium nucleatum, NESG Target NR1 To be Published
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1I4S
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2EB1
| Crystal Structure of the C-Terminal RNase III Domain of Human Dicer | 分子名称: | Endoribonuclease Dicer, MAGNESIUM ION | 著者 | Takeshita, D, Zenno, S, Lee, W.C, Nagata, K, Saigo, K, Tanokura, M. | 登録日 | 2007-02-05 | 公開日 | 2007-11-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Homodimeric Structure and Double-stranded RNA Cleavage Activity of the C-terminal RNase III Domain of Human Dicer J.Mol.Biol., 374, 2007
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4OUN
| Crystal Structure of Mini-ribonuclease 3 from Bacillus subtilis | 分子名称: | Mini-ribonuclease 3 | 著者 | Chojnowski, G, Czarnecka, J, Nowak, E, Pianka, D, Glow, D, Sabala, I, Skowronek, K, Nowotny, M, Bujnicki, J.M. | 登録日 | 2014-02-18 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Sequence-specific cleavage of dsRNA by Mini-III RNase Nucleic Acids Res., 43, 2015
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1JFZ
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1RC5
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1U61
| Crystal Structure of Putative Ribonuclease III from Bacillus cereus | 分子名称: | hypothetical protein | 著者 | Osipiuk, J, Quartey, P, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2004-07-29 | 公開日 | 2004-09-21 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | X-ray crystal structure of conserved hypothetical protein from Bacillus cereus To be Published
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2FFL
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2QVW
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3C4B
| Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer | 分子名称: | Endoribonuclease Dicer | 著者 | Lee, J.K, Du, Z, Tjhen, R.J, Stroud, R.M, James, T.L. | 登録日 | 2008-01-29 | 公開日 | 2008-02-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3C4T
| Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer | 分子名称: | CADMIUM ION, Endoribonuclease Dicer | 著者 | Lee, J.K, Du, Z, Tjhen, R.J, Stroud, R.M, James, T.L. | 登録日 | 2008-01-30 | 公開日 | 2008-02-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3RV1
| Crystal structure of the N-terminal and RNase III domains of K. polysporus Dcr1 E224Q mutant | 分子名称: | K. polysporus Dcr1 | 著者 | Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J. | 登録日 | 2011-05-05 | 公開日 | 2011-08-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.975 Å) | 主引用文献 | The inside-out mechanism of dicers from budding yeasts. Cell(Cambridge,Mass.), 146, 2011
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6V5B
| Human Drosha and DGCR8 in complex with Primary MicroRNA (MP/RNA complex) - Active state | 分子名称: | CALCIUM ION, Microprocessor complex subunit DGCR8, Pri-miR-16-2 (78-MER), ... | 著者 | Partin, A, Zhang, K, Jeong, B, Herrell, E, Li, S, Chiu, W, Nam, Y. | 登録日 | 2019-12-04 | 公開日 | 2020-04-08 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA. Mol.Cell, 78, 2020
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6V5C
| Human Drosha and DGCR8 in complex with Primary MicroRNA (MP/RNA complex) - partially docked state | 分子名称: | Microprocessor complex subunit DGCR8, Pri-miR-16-2 (66-MER), Ribonuclease 3 | 著者 | Partin, A, Zhang, K, Jeong, B, Herrell, E, Li, S, Chiu, W, Nam, Y. | 登録日 | 2019-12-04 | 公開日 | 2020-04-08 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA. Mol.Cell, 78, 2020
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3J6B
| Structure of the yeast mitochondrial large ribosomal subunit | 分子名称: | 21S ribosomal RNA, 54S ribosomal protein IMG1, mitochondrial, ... | 著者 | Amunts, A, Brown, A, Bai, X.C, Llacer, J.L, Hussain, T, Emsley, P, Long, F, Murshudov, G, Scheres, S.H.W, Ramakrishnan, V. | 登録日 | 2014-01-22 | 公開日 | 2014-04-09 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of the yeast mitochondrial large ribosomal subunit. Science, 343, 2014
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5T16
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6TNN
| Mini-RNase III (Mini-III) bound to 50S ribosome with precursor 23S rRNA | 分子名称: | 50S ribosomal protein L10, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Oerum, S, Dendooven, T, Gilet, L, Catala, M, Degut, C, Trinquier, A, Barraud, P, Luisi, B, Condon, C, Tisne, C. | 登録日 | 2019-12-09 | 公開日 | 2020-09-30 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs. Mol.Cell, 80, 2020
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5B16
| X-ray structure of DROSHA in complex with the C-terminal tail of DGCR8. | 分子名称: | Microprocessor complex subunit DGCR8, Ribonuclease 3,DROSHA,Ribonuclease 3,DROSHA,Ribonuclease 3, ZINC ION | 著者 | Kwon, S.C, Nguyen, T.A, Choi, Y.G, Jo, M.H, Hohng, S, Kim, V.N, Woo, J.S. | 登録日 | 2015-11-23 | 公開日 | 2016-02-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of Human DROSHA Cell, 164, 2016
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6LXD
| Pri-miRNA bound DROSHA-DGCR8 complex | 分子名称: | Microprocessor complex subunit DGCR8, RNA (102-mer), Ribonuclease 3, ... | 著者 | Jin, W, Wang, J, Liu, C.P, Wang, H.W, Xu, R.M. | 登録日 | 2020-02-10 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural Basis for pri-miRNA Recognition by Drosha. Mol.Cell, 78, 2020
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4M2Z
| Crystal structure of RNASE III complexed with double-stranded RNA and CMP (TYPE II CLEAVAGE) | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, MAGNESIUM ION, RNA10, ... | 著者 | Gan, J, Liang, Y.-H, Shaw, G.X, Tropea, J.E, Waugh, D.S, Ji, X. | 登録日 | 2013-08-05 | 公開日 | 2013-12-11 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | RNase III: Genetics and Function; Structure and Mechanism. Annu. Rev. Genet., 47, 2013
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4M30
| Crystal structure of RNASE III complexed with double-stranded RNA AND AMP (TYPE II CLEAVAGE) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... | 著者 | Gan, J, Liang, Y.-H, Shaw, G.X, Tropea, J.E, Waugh, D.S, Ji, X. | 登録日 | 2013-08-05 | 公開日 | 2013-12-11 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | RNase III: Genetics and Function; Structure and Mechanism. Annu. Rev. Genet., 47, 2013
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6LXE
| DROSHA-DGCR8 complex | 分子名称: | Microprocessor complex subunit DGCR8, Ribonuclease 3, ZINC ION | 著者 | Jin, W, Wang, J, Liu, C.P, Wang, H.W, Xu, R.M. | 登録日 | 2020-02-10 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural Basis for pri-miRNA Recognition by Drosha. Mol.Cell, 78, 2020
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6BUA
| Drosophila Dicer-2 apo homology model (helicase, Platform-PAZ, RNaseIII domains) | 分子名称: | Dicer-2, isoform A | 著者 | Shen, P.S, Sinha, N.K, Bass, B.L. | 登録日 | 2017-12-09 | 公開日 | 2017-12-27 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | 主引用文献 | Dicer uses distinct modules for recognizing dsRNA termini. Science, 359, 2018
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8HF0
| DmDcr-2/R2D2/LoqsPD with 50bp-dsRNA in Dimer state | 分子名称: | Dicer-2, isoform A, LD06392p, ... | 著者 | Su, S, Wang, J, Wang, H.W, Ma, J. | 登録日 | 2022-11-09 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers. Nat Commun, 14, 2023
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8HF1
| DmDcr-2/R2D2/LoqsPD with 19bp-dsRNA in Trimer state | 分子名称: | Dicer-2, isoform A, LD06392p, ... | 著者 | Su, S, Wang, J, Ma, J. | 登録日 | 2022-11-09 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers. Nat Commun, 14, 2023
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