2EB1

Crystal Structure of the C-Terminal RNase III Domain of Human Dicer

Summary for 2EB1

Entry DOI	10.2210/pdb2eb1/pdb
Descriptor	Endoribonuclease Dicer, MAGNESIUM ION (3 entities in total)
Functional Keywords	rna-binding, nuclease, hydrolase, endonuclease
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q9UPY3
Total number of polymer chains	3
Total formula weight	71055.80
Authors	Takeshita, D.,Zenno, S.,Lee, W.C.,Nagata, K.,Saigo, K.,Tanokura, M. (deposition date: 2007-02-05, release date: 2007-11-06, Last modification date: 2023-10-25)
Primary citation	Takeshita, D.,Zenno, S.,Lee, W.C.,Nagata, K.,Saigo, K.,Tanokura, M. Homodimeric Structure and Double-stranded RNA Cleavage Activity of the C-terminal RNase III Domain of Human Dicer J.Mol.Biol., 374:106-120, 2007 Cited by PubMed: 17920623 DOI: 10.1016/j.jmb.2007.08.069 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation