2EB1

Crystal Structure of the C-Terminal RNase III Domain of Human Dicer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Endoribonuclease Dicer	polymer	200	23636.7	3	UniProt (Q9UPY3) Pfam (PF00636) In PDB	Homo sapiens (human)	Ribonuclease III, Helicase with RNase motif, Helicase-MOI
2	A, B, C	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
3		water	water		18.0	192	Chemie (HOH)

Sequence modifications

A, B, C: 2 - 194 (UniProt: Q9UPY3)

PDB	External Database	Details
Met 1	-	initiating methionine
His 195	-	expression tag
His 196	-	expression tag
His 197	-	expression tag
His 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	70910.0
Non-Polymers*	Number of molecules	6
	Total formula weight	145.8
All*	Total formula weight	71055.8

*Water molecules are not included.