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2EB1

Crystal Structure of the C-Terminal RNase III Domain of Human Dicer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Endoribonuclease Dicerpolymer20023636.73UniProt (Q9UPY3)
Pfam (PF00636)
Homo sapiens (human)Ribonuclease III, Helicase with RNase motif, Helicase-MOI
2D, E, F, G, H...
(A, B, C)
MAGNESIUM IONnon-polymer24.36Chemie (MG)
3J, K, L
(A, B, C)
waterwater18.0192Chemie (HOH)
Sequence modifications
A, B, C: 2 - 194 (UniProt: Q9UPY3)
PDBExternal DatabaseDetails
Met 1-initiating methionine
His 195-expression tag
His 196-expression tag
His 197-expression tag
His 198-expression tag
His 199-expression tag
His 200-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight70910.0
Non-Polymers*Number of molecules6
Total formula weight145.8
All*Total formula weight71055.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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