8XWP
 
 | | Cryo-EM structure of ET-1 bound ETBR-DNGI complex | | 分子名称: | Endothelin receptor type B, Endothelin-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Tani, K, Maki-Yonekura, S, Kanno, R, Negami, T, Hamaguchi, T, Hall, M, Mizoguchi, A, Humbel, B.M, Terada, T, Yonekura, K, Doi, T. | | 登録日 | 2024-01-16 | | 公開日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Structure of endothelin ETB receptor-Gi complex in a conformation stabilized by the unique NPxxL motif
Commun Biol, 2024
|
|
8XWQ
 | | Cryo-EM structure of ET-1 bound ETBR-DNGI complex | | 分子名称: | Endothelin receptor type B, Endothelin-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Tani, K, Maki-Yonekura, S, Kanno, R, Negami, T, Hamaguchi, T, Hall, M, Mizoguchi, A, Humbel, B.M, Terada, T, Yonekura, K, Doi, T. | | 登録日 | 2024-01-16 | | 公開日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structure of endothelin ETB receptor-Gi complex in a conformation stabilized by the unique NPxxL motif
Commun Biol, 2024
|
|
9IQT
 | | structure of niacin-HCA2-Gi | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Liu, Y, Zhou, Z. | | 登録日 | 2024-07-13 | | 公開日 | 2024-10-02 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Ligand recognition and activation mechanism of the alicarboxylic acid receptors.
J.Mol.Biol., 2024
|
|
8WJX
 | |
8ZPT
 | | Cryo-EM structure of prolactin-releasing peptide recognition with Gq | | 分子名称: | Guanine nucleotide-binding protein G(324) subunit alpha-1,, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhao, L, Li, Y, Yuan, Q, Xu, H.E. | | 登録日 | 2024-05-31 | | 公開日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | Molecular mechanism of prolactin-releasing peptide recognition and signaling via its G protein-coupled receptor.
Cell Discov, 10, 2024
|
|
8ZPS
 | | Cryo-EM structure of prolactin-releasing peptide recognition with Gi | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha-1, ... | | 著者 | Zhao, L, Li, Y, Yuan, Q, Xu, H.E. | | 登録日 | 2024-05-31 | | 公開日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Molecular mechanism of prolactin-releasing peptide recognition and signaling via its G protein-coupled receptor.
Cell Discov, 10, 2024
|
|
8QJ2
 | |
9F33
 | |
9F34
 | |
8XOR
 | |
8YW4
 | | Cryo-EM structure of the retatrutide-bound human GIPR-Gs complex | | 分子名称: | Gastric inhibitory polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Li, W.Z, Zhou, Q.T, Cong, Z.T, Yuan, Q.N, Li, W.X, Zhao, F.H, Xu, H.E, Zhao, L.H, Yang, D.H, Wang, M.W. | | 登録日 | 2024-03-29 | | 公開日 | 2024-09-18 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide.
Cell Discov, 10, 2024
|
|
8XOS
 | | Cryo-EM structure of the tethered agonist-bound human PAR1-Gi complex | | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Guo, J, Zhang, Y. | | 登録日 | 2024-01-02 | | 公開日 | 2024-09-18 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis of tethered agonism and G protein coupling of protease-activated receptors.
Cell Res., 34, 2024
|
|
8YW3
 | | Cryo-EM structure of the retatrutide-bound human GLP-1R-Gs complex | | 分子名称: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Li, W.Z, Zhou, Q.T, Cong, Z.T, Yuan, Q.N, Li, W.X, Zhao, F.H, Xu, H.E, Zhao, L.H, Yang, D.H, Wang, M.W. | | 登録日 | 2024-03-29 | | 公開日 | 2024-09-18 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide.
Cell Discov, 10, 2024
|
|
8WP1
 | | Cryo-EM structure of SUCR1 in complex with cis-epoxysuccinic acid and Gi proteins | | 分子名称: | (2R,3S)-oxirane-2,3-dicarboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Liu, A, Ye, R.D. | | 登録日 | 2023-10-08 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Structural insights into ligand recognition and activation of the succinate receptor SUCNR1.
Cell Rep, 43, 2024
|
|
8Y53
 | | Cryo-EM structure of the MK-5046-bound BRS3-Gq complex | | 分子名称: | (2~{S})-1,1,1-tris(fluoranyl)-2-(4-pyrazol-1-ylphenyl)-3-[5-[[1-(trifluoromethyl)cyclopropyl]methyl]-1~{H}-imidazol-2-yl]propan-2-ol, Bombesin receptor subtype-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Li, C, Xu, Y, Yin, W, Xu, H.E. | | 登録日 | 2024-01-31 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Structural insights into ligand recognition, selectivity, and activation of bombesin receptor subtype-3.
Cell Rep, 43, 2024
|
|
8WOG
 | | Cryo-EM structure of SUCR1 in complex with succinate and Gi protein | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Liu, A, Ye, R.D. | | 登録日 | 2023-10-07 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structural insights into ligand recognition and activation of the succinate receptor SUCNR1.
Cell Rep, 43, 2024
|
|
8Y52
 | | Cryo-EM structure of the BA1-bound BRS3-Gq complex | | 分子名称: | BA1, Bombesin receptor subtype-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Li, C, Xu, Y, Yin, W, Xu, H.E. | | 登録日 | 2024-01-31 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural insights into ligand recognition, selectivity, and activation of bombesin receptor subtype-3.
Cell Rep, 43, 2024
|
|
9BQJ
 | | RO76 bound muOR-Gi1-scFv16 complex structure | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Wang, H, Majumdar, S, Kobilka, B.K. | | 登録日 | 2024-05-10 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Signaling Modulation Mediated by Ligand Water Interactions with the Sodium Site at mu OR.
Acs Cent.Sci., 10, 2024
|
|
9CBL
 | | Cryo-EM structure of epinephrine-bound alpha-2A-adrenergic receptor in complex with heterotrimeric Gi-protein | | 分子名称: | Endolysin,Alpha-2A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Lou, J.S, Su, M, Wang, J, Do, H.N, Miao, Y, Huang, X.Y. | | 登録日 | 2024-06-19 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Distinct binding conformations of epinephrine with alpha- and beta-adrenergic receptors.
Exp.Mol.Med., 56, 2024
|
|
9CBM
 | | Cryo-EM structure of dexmedetomidine-bound alpha-2A-adrenergic receptor in complex with heterotrimeric Gi-protein | | 分子名称: | 4-[(1~{S})-1-(2,3-dimethylphenyl)ethyl]-1~{H}-imidazole, Endolysin,Alpha-2A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Lou, J.S, Su, M, Wang, J, Do, H.N, Miao, Y, Huang, X.Y. | | 登録日 | 2024-06-19 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Distinct binding conformations of epinephrine with alpha- and beta-adrenergic receptors.
Exp.Mol.Med., 56, 2024
|
|
8XVI
 | | Cryo-EM structure of ETAR bound with Endothelin1 | | 分子名称: | Endoglucanase H,Endothelin-1 receptor, Endothelin-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Hou, J.Y, Liu, S.H, Wu, L.J, Liu, Z.J, Hua, T. | | 登録日 | 2024-01-15 | | 公開日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Structural basis of antagonist selectivity in endothelin receptors.
Cell Discov, 10, 2024
|
|
8XVH
 | | Cryo-EM structure of ETBR bound with Endothelin1 | | 分子名称: | Endothelin-1, Exo-alpha-sialidase,Endothelin receptor type B, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Hou, J.Y, Liu, S.H, Wu, L.J, Liu, Z.J, Hua, T. | | 登録日 | 2024-01-15 | | 公開日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Structural basis of antagonist selectivity in endothelin receptors.
Cell Discov, 10, 2024
|
|
8XVE
 | | Cryo-EM structure of ETBR bound with BQ3020 | | 分子名称: | BQ3020, Exo-alpha-sialidase,Endothelin receptor type B, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Hou, J.Y, Liu, S.H, Wu, L.J, Liu, Z.J, Hua, T. | | 登録日 | 2024-01-15 | | 公開日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of antagonist selectivity in endothelin receptors.
Cell Discov, 10, 2024
|
|
9IJD
 | | Carazolol-activated human beta3 adrenergic receptor | | 分子名称: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, Beta-3 adrenergic receptor, Camelid antibody VHH fragment, ... | | 著者 | Zheng, S, Zhang, S, Dai, S, Chen, K, Gao, K, Lin, B, Liu, X. | | 登録日 | 2024-06-22 | | 公開日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Molecular Mechanism of the beta 3AR Agonist Activity of a beta-Blocker.
Chempluschem, 2024
|
|
8XGM
 | |
