8Y52

Cryo-EM structure of the BA1-bound BRS3-Gq complex

Summary for 8Y52

• Entry DOI: 10.2210/pdb8y52/pdb
• EMDB information: 38928
• Descriptor: Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total)
• Functional Keywords: gpcr, bombesin receptor subtype-3 receptor, ba1, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 129138.53

Authors

Li, C.,Xu, Y.,Yin, W.,Xu, H.E. (deposition date: 2024-01-31, release date: 2024-09-11)

• Primary citation: Li, C.,Xu, Y.,Su, W.,He, X.,Li, J.,Li, X.,Xu, H.E.,Yin, W.; Structural insights into ligand recognition, selectivity, and activation of bombesin receptor subtype-3.; Cell Rep, 43:114511-114511, 2024; PubMed: 39024101; DOI: 10.1016/j.celrep.2024.114511

Experimental method

ELECTRON MICROSCOPY (2.9 Å)