9BQJ

RO76 bound muOR-Gi1-scFv16 complex structure

This is a non-PDB format compatible entry.

Summary for 9BQJ

• Entry DOI: 10.2210/pdb9bqj/pdb
• EMDB information: 44812
• Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Mu-type opioid receptor, ... (7 entities in total)
• Functional Keywords: gpcr, g protein, opioid receptor, signaling protein-immune system complex, signaling protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 154107.80

Authors

Wang, H.,Majumdar, S.,Kobilka, B.K. (deposition date: 2024-05-10, release date: 2024-09-11, Last modification date: 2024-10-09)

• Primary citation: Ople, R.S.,Ramos-Gonzalez, N.,Li, Q.,Sobecks, B.L.,Aydin, D.,Powers, A.S.,Faouzi, A.,Polacco, B.J.,Bernhard, S.M.,Appourchaux, K.,Sribhashyam, S.,Eans, S.O.,Tsai, B.A.,Dror, R.O.,Varga, B.R.,Wang, H.,Huttenhain, R.,McLaughlin, J.P.,Majumdar, S.; Signaling Modulation Mediated by Ligand Water Interactions with the Sodium Site at mu OR.; Acs Cent.Sci., 10:1490-1503, 2024; PubMed: 39220695; DOI: 10.1021/acscentsci.4c00525

Experimental method

ELECTRON MICROSCOPY (3.3 Å)