8XWP

Cryo-EM structure of ET-1 bound ETBR-DNGI complex

Summary for 8XWP

Entry DOI	10.2210/pdb8xwp/pdb
EMDB information	38740
Descriptor	Endothelin receptor type B, Endothelin-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (6 entities in total)
Functional Keywords	endothelin, receptor, gi, complex, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	156651.43
Authors	Tani, K.,Maki-Yonekura, S.,Kanno, R.,Negami, T.,Hamaguchi, T.,Hall, M.,Mizoguchi, A.,Humbel, B.M.,Terada, T.,Yonekura, K.,Doi, T. (deposition date: 2024-01-16, release date: 2024-10-02)
Primary citation	Tani, K.,Maki-Yonekura, S.,Kanno, R.,Negami, T.,Hamaguchi, T.,Hall, M.,Mizoguchi, A.,Humbel, B.M.,Terada, T.,Yonekura, K.,Doi, T. Structure of endothelin ETB receptor-Gi complex in a conformation stabilized by the unique NPxxL motif Commun Biol, 2024 Cited by DOI: 10.1038/s42003-024-06905-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.21 Å)

Structure validation