9F33
Cryo-EM structure of Dopamine 3 Receptor:Go complex bound to bitopic FOB02-04A - Conformation A
This is a non-PDB format compatible entry.
Summary for 9F33
Entry DOI | 10.2210/pdb9f33/pdb |
EMDB information | 50168 |
Descriptor | Guanine nucleotide-binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | gpcr, dopamine, bitopic, receptor, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 191428.30 |
Authors | Arroyo-Urea, S.,Garcia-Nafria, J. (deposition date: 2024-04-24, release date: 2024-09-18, Last modification date: 2024-10-16) |
Primary citation | Arroyo-Urea, S.,Nazarova, A.L.,Carrion-Antoli, A.,Bonifazi, A.,Battiti, F.O.,Lam, J.H.,Newman, A.H.,Katritch, V.,Garcia-Nafria, J. A bitopic agonist bound to the dopamine 3 receptor reveals a selectivity site. Nat Commun, 15:7759-7759, 2024 Cited by PubMed: 39237617DOI: 10.1038/s41467-024-51993-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.05 Å) |
Structure validation
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