9BP9
 
 | | Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, dimer form | | 分子名称: | (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta | | 著者 | Ito, F, Li, Z, Chen, X.S. | | 登録日 | 2024-05-07 | | 公開日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM.
Nat Commun, 15, 2024
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9BPA
 | | Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, tetramer form | | 分子名称: | (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta | | 著者 | Ito, F, Li, Z, Chen, X.S. | | 登録日 | 2024-05-07 | | 公開日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM.
Nat Commun, 15, 2024
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8RO1
 | | Structure of the C. elegans Intron Lariat Spliceosome double-primed for disassembly (ILS'') | | 分子名称: | CWF19-like protein 1 homolog, CWF19-like protein 2 homolog, Cell division cycle 5-like protein, ... | | 著者 | Vorlaender, M.K, Rothe, P, Plaschka, C. | | 登録日 | 2024-01-11 | | 公開日 | 2024-08-07 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanism for the initiation of spliceosome disassembly.
Nature, 632, 2024
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8RO0
 | | Structure of the C. elegans Intron Lariat Spliceosome primed for disassembly (ILS') | | 分子名称: | Cell division cycle 5-like protein, Coiled-coil domain-containing protein 12, GCF C-terminal domain-containing protein, ... | | 著者 | Vorlaender, M.K, Rothe, P, Plaschka, C. | | 登録日 | 2024-01-11 | | 公開日 | 2024-08-07 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Mechanism for the initiation of spliceosome disassembly.
Nature, 632, 2024
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8I0V
 | | The cryo-EM structure of human post-Bact complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2023-01-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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8I0P
 | | The cryo-EM structure of human pre-Bact complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2023-01-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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8I0W
 | | The cryo-EM structure of human C complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Coiled-coil domain-containing protein 94, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2023-01-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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8I0R
 | | The cryo-EM structure of human Bact-I complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2023-01-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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8I0U
 | | The cryo-EM structure of human Bact-IV complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2023-01-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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8I0T
 | | The cryo-EM structure of human Bact-III complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2023-01-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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8I0S
 | | The cryo-EM structure of human Bact-II complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2023-01-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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8WTK
 | | Crystal structure of Cas3-DExD+MG | | 分子名称: | CRISPR-associated helicase Cas3, MAGNESIUM ION | | 著者 | Mo, X. | | 登録日 | 2023-10-18 | | 公開日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | | 主引用文献 | Structural insight into dynamic characteristic of the polymerized forms of kinetoplastid membrane protein-11
To be published
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9FMD
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9ASK
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9C5Q
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9ASL
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9ASJ
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8W0A
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8SSW
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8QPA
 | | Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part) | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | | 登録日 | 2023-10-01 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
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8QPB
 | | Cryo-EM Structure of Pre-B+ATP Complex (core part) | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | | 登録日 | 2023-10-01 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
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8R0B
 | | Cryo-EM structure of the cross-exon pre-B+ATP complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ... | | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | | 登録日 | 2023-10-31 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
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8R08
 | | Cryo-EM structure of the cross-exon pre-B+AMPPNP complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ... | | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | | 登録日 | 2023-10-31 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
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8QP9
 | | Cryo-EM Structure of Pre-B+AMPPNP Complex (core part) | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Pre-mRNA-processing factor 6, ... | | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | | 登録日 | 2023-09-30 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
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8QPK
 | | Cryo-EM Structure of Pre-B+5'ss Complex (core part) | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | | 登録日 | 2023-10-02 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
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