9C5Q

Human DNA polymerase theta helicase domain in microhomology annealed state 2, dimer form

Summary for 9C5Q

• Entry DOI: 10.2210/pdb9c5q/pdb
• EMDB information: 45218
• Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*CP*CP*CP*GP*GP*G)-3'), DNA polymerase theta (2 entities in total)
• Functional Keywords: dna repair, helicase, atpase, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 192667.09

Authors

Ito, F.,Li, Z.,Chen, X.S. (deposition date: 2024-06-06, release date: 2024-06-26)

• Primary citation: Ito, F.,Li, Z.,Minakhin, L.,Khant, H.A.,Pomerantz, R.T.,Chen, X.S.; Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.; Biorxiv, 2024; PubMed: 38895274; DOI: 10.1101/2024.06.07.597860

Experimental method

ELECTRON MICROSCOPY (3.1 Å)