PDB: 199 件ウェブページステータス検索Chemie searchBIRD

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4RDU	Crystal structure of a distal-less homeobox protein 5 (Dlx5) from Homo sapiens at 1.85 A resolution 分子名称: (DC)(DG)(DA)(DC)(DT)(DA)(DA)(DT)(DT)(DA)(DG)(DT)(DC)(DG), Homeobox protein DLX-5 著者 Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2014-09-19 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of a distal-less homeobox protein 5 (Dlx5) from Homo sapiens at 1.85 A resolution To be published
4RBO	Crystal structure of a Nanog homeobox (NANOG) from Homo sapiens at 3.30 A resolution 分子名称: 5'-D(*CP*TP*TP*GP*AP*AP*TP*GP*GP*GP*CP*C)-3', 5'-D(*GP*GP*CP*CP*CP*AP*TP*TP*CP*AP*AP*G)-3', Putative homeobox protein NANOGP8 著者 Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2014-09-12 公開日 2014-10-01 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells. Proc.Natl.Acad.Sci.USA, 112, 2015
6ES2	Structure of CDX2-DNA(CAA) 分子名称: DNA (5'-D(P*GP*GP*AP*GP*GP*CP*AP*AP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*TP*TP*GP*CP*CP*TP*CP*C)-3'), Homeobox protein CDX-2 著者 Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J. 登録日 2017-10-19 公開日 2018-03-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima. Elife, 7, 2018
1QRY	Homeobox protein VND (ventral nervous system defective protein) 分子名称: PROTEIN (HOMEOBOX VENTRAL NERVOUS SYSTEM DEFECTIVE PROTEIN) 著者 Xiang, B. 登録日 1999-06-16 公開日 1999-07-06 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Distortion of the three-dimensional structure of the vnd/NK-2 homeodomain bound to DNA induced by an embryonically lethal A35T point mutation. Biochemistry, 42, 2003
4J19	Structure of a novel telomere repeat binding protein bound to DNA 分子名称: CHLORIDE ION, DNA (5'-D(*CP*TP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*A)-3'), ... 著者 Kappei, D, Butter, F, Benda, C, Scheibe, M, Draskovic, I, Stevense, M, Lopes Novo, C, Basquin, C, Krastev, D.B, Kittler, R, Jessberger, R, Londono-Vallejo, A.J, Mann, M, Buchholz, F. 登録日 2013-02-01 公開日 2013-05-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment. Embo J., 32, 2013
6M3D	X-ray crystal structure of tandemly connected engrailed homeodomains (EHD) with R53A mutations and DNA complex 分子名称: DNA (5'-D(*GP*GP*AP*TP*TP*AP*GP*GP*AP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*TP*CP*CP*TP*AP*AP*TP*CP*C)-3'), SODIUM ION, ... 著者 Sunami, T, Hirano, Y, Tamada, T, Kono, H. 登録日 2020-03-03 公開日 2020-09-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural basis for designing an array of engrailed homeodomains. Acta Crystallogr D Struct Biol, 76, 2020
3ZOB	Solution structure of chicken Engrailed 2 homeodomain 分子名称: HOMEOBOX PROTEIN ENGRAILED-2 著者 Carlier, L, Balayssac, S, Cantrelle, F.X, Khemtemourian, L, Chassaing, G, Joliot, A, Lequin, O. 登録日 2013-02-21 公開日 2013-08-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Investigation of Homeodomain Membrane Translocation Properties: Insights from the Structure Determination of Engrailed-2 Homeodomain in Aqueous and Membrane-Mimetic Environments. Biophys.J., 105, 2013
3HDD	ENGRAILED HOMEODOMAIN DNA COMPLEX 分子名称: 5'-D(*AP*TP*TP*AP*GP*GP*TP*AP*AP*TP*TP*AP*CP*AP*TP*GP*GP*CP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*TP*AP*CP*CP*TP*AP*A)-3', ENGRAILED HOMEODOMAIN 著者 Fraenkel, E, Rould, M.A, Chambers, K.A, Pabo, C.O. 登録日 1998-07-13 公開日 1998-11-11 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Engrailed homeodomain-DNA complex at 2.2 A resolution: a detailed view of the interface and comparison with other engrailed structures. J.Mol.Biol., 284, 1998
7DW5	Crystal structure of DUX4 HD1-HD2 domain complexed with ERG sites 分子名称: BROMIDE ION, DNA (5'-D(P*CP*GP*AP*CP*TP*TP*GP*AP*TP*GP*AP*GP*AP*TP*TP*AP*GP*AP*CP*TP*G)-3'), Double homeobox protein 4-like protein 2 著者 Zhang, H, Cheng, N, Li, Z, Zhang, W, Dong, X, Huang, J, Meng, G. 登録日 2021-01-15 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 DNA crosslinking and recombination-activating genes 1/2 (RAG1/2) are required for oncogenic splicing in acute lymphoblastic leukemia. Cancer Commun (Lond), 41, 2021
4XIC	ANTPHD WITH 15BP di-thioate modified DNA DUPLEX 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C2S)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ... 著者 White, M.A, Zandarashvili, L, Iwahara, J. 登録日 2015-01-06 公開日 2015-11-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate. Biophys.J., 109, 2015
3LNQ	Structure of Aristaless homeodomain in complex with DNA 分子名称: 5'-D(*CP*CP*CP*TP*AP*AP*TP*TP*AP*AP*AP*CP*CP*C)-3', 5'-D(*GP*GP*GP*TP*TP*TP*AP*AP*TP*TP*AP*GP*GP*G)-3', ACETATE ION, ... 著者 Takamura, Y, Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M. 登録日 2010-02-02 公開日 2010-04-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless Embo J., 29, 2010
6FVC	Protein environment affects the water-tryptophan binding mode. Molecular dynamics simulations of Engrailed homeodomain mutants 分子名称: Segmentation polarity homeobox protein engrailed 著者 Trosanova, Z, Zachrdla, M, Jansen, S, Srb, P, Zidek, L, Kozelka, J. 登録日 2018-03-02 公開日 2019-04-03 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Protein environment affects the water-tryptophan binding mode. MD, QM/MM, and NMR studies of engrailed homeodomain mutants. Phys Chem Chem Phys, 20, 2018
3CMY	Structure of a homeodomain in complex with DNA 分子名称: 1,2-ETHANEDIOL, 5'-D(*DAP*DCP*DAP*DTP*DAP*DAP*DP*DCP*DGP*DAP*DTP*DTP*DAP*DC)-3', 5'-D(*DTP*DGP*DTP*DAP*DAP*DTP*DCP*DGP*DAP*DTP*DTP*DAP*DTP*DG)-3', ... 著者 Birrane, G, Ladias, J.A.A, Soni, A. 登録日 2008-03-24 公開日 2009-02-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Basis for DNA Recognition by the Human PAX3 Homeodomain. Biochemistry, 48, 2009
9ANT	ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX 分子名称: ANTENNAPEDIA HOMEODOMAIN, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ... 著者 Fraenkel, E, Pabo, C.O. 登録日 1998-07-02 公開日 1998-10-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Comparison of X-ray and NMR structures for the Antennapedia homeodomain-DNA complex. Nat.Struct.Biol., 5, 1998
5HOD	Structure of LHX4 transcription factor complexed with DNA 分子名称: DNA (5'-D(P*AP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*CP*GP*TP*AP*AP*TP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*AP*TP*TP*AP*CP*GP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*T)-3'), LIM/homeobox protein Lhx4 著者 Morgunova, E, Yin, Y, Popov, A, Taipale, J. 登録日 2016-01-19 公開日 2017-02-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.682 Å) 主引用文献 Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science, 356, 2017
9B8U	Crystal structure of CRX-Ret4 oligonucleotide complex 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Cone-rod homeobox protein, ... 著者 Srivastava, D, Artemyev, N.O. 登録日 2024-04-01 公開日 2024-07-31 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Molecular basis of CRX/DNA recognition and stoichiometry at the Ret4 response element. Structure, 2024
8BYX	HOXB13-homodimer bound to DNA 分子名称: DNA, Homeobox protein Hox-B13 著者 Morgunova, E, Popov, A, Yin, Y, Taipale, J. 登録日 2022-12-14 公開日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 HOXB13-homodimer bound to DNA To Be Published
4UUT	Crystal structure of the Ultrabithorax protein 分子名称: CHLORIDE ION, HOMEOTIC PROTEIN ULTRABITHORAX, SULFATE ION 著者 Foos, N, Mate, M.J, Ortiz-Lombardia, M. 登録日 2014-07-31 公開日 2015-02-18 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A Flexible Extension of the Drosophila Ultrabithorax Homeodomain Defines a Novel Hox/Pbc Interaction Mode. Structure, 23, 2015
2KT0	Solution structure of human stem cell transcription factor Nanog homeodomain fragment 分子名称: Homeobox protein NANOG 著者 Sahu, S.C, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) 登録日 2010-01-15 公開日 2010-02-02 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Solution structure of human stem cell transcription factor Nanog To be Published
7PSX	Structure of HOXB13 bound to hydroxymethylated DNA 分子名称: DNA (5'-D(P*GP*GP*AP*CP*CP*TP*5HCP*AP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*CP*GP*AP*GP*GP*TP*CP*C)-3'), Homeobox protein Hox-B13, ... 著者 Morgunova, E, Popov, A, Yin, Y, Taipale, J. 登録日 2021-09-24 公開日 2022-10-05 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of HOXB13 bound to hydroxymethylated DNA To Be Published
7Q3O	Structure of CDX1 bound to hydroxymethylated DNA 分子名称: Homeobox protein CDX-1, hydroxymethylated DNA (18-MER) 著者 Morgunova, E, Yin, Y, Popov, A, Taipale, J. 登録日 2021-10-28 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Structure of CDX1 bound to hydroxymethylated DNA To Be Published
7Q4N	transcription factor CDX2 bound to hydroxymethylated DNA 分子名称: DNA (18-MER), Homeobox protein CDX-2 著者 Morgunova, E, Yin, Y, Popov, A, Taipale, J. 登録日 2021-11-01 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 transcription factor CDX2 bound to hydroxymethylated DNA To Be Published
2LD5	Solution NMR-derived complex structure of Hoxa13 DNA binding domain bound to DNA 分子名称: DNA (5'-D(*CP*AP*AP*AP*TP*AP*AP*AP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*TP*TP*TP*AP*TP*TP*TP*G)-3'), Homeobox protein Hox-A13 著者 Zhang, Y. 登録日 2011-05-14 公開日 2011-08-10 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural basis for sequence specific DNA binding and protein dimerization of HOXA13. Plos One, 6, 2011
6DFY	Remodeled crystal structure of DNA-bound DUX4-HD2 分子名称: DNA (5'-D(*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*A)-3'), Double homeobox protein 4 著者 Aihara, H, Shi, K. 登録日 2018-05-15 公開日 2018-09-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.623 Å) 主引用文献 Comment on structural basis of DUX4/IGH-driven transactivation. Leukemia, 32, 2018
2L9R	Solution NMR Structure of Homeobox domain of Homeobox protein Nkx-3.1 from homo sapiens, Northeast Structural Genomics Consortium Target HR6470A 分子名称: Homeobox protein Nkx-3.1 著者 Liu, G, Xiao, R, Lee, H.-W, Hamilton, K, Ciccosanti, C, Wang, H.B, Acton, T.B, Everett, J.K, Huang, Y.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2011-02-22 公開日 2011-04-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of Homeobox domain of Homeobox protein Nkx-3.1 from homo sapiens, Northeast Structural Genomics Consortium Target HR6470A To be Published

 

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