6FVC

Protein environment affects the water-tryptophan binding mode. Molecular dynamics simulations of Engrailed homeodomain mutants

Summary for 6FVC

• Entry DOI: 10.2210/pdb6fvc/pdb
• NMR Information: BMRB: 34240
• Descriptor: Segmentation polarity homeobox protein engrailed (2 entities in total)
• Functional Keywords: engrailed homeodomain, k52e mutation, dna, dna binding protein
• Biological source: Drosophila melanogaster (Fruit fly)
• Total number of polymer chains: 1
• Total formula weight: 7626.66

Authors

Trosanova, Z.,Zachrdla, M.,Jansen, S.,Srb, P.,Zidek, L.,Kozelka, J. (deposition date: 2018-03-02, release date: 2019-04-03, Last modification date: 2023-06-14)

• Primary citation: Spackova, N.,Trosanova, Z.,Sebesta, F.,Jansen, S.,Burda, J.V.,Srb, P.,Zachrdla, M.,Zidek, L.,Kozelka, J.; Protein environment affects the water-tryptophan binding mode. MD, QM/MM, and NMR studies of engrailed homeodomain mutants.; Phys Chem Chem Phys, 20:12664-, 2018; DOI: 10.1039/c7cp08623g

Experimental method

SOLUTION NMR