PDB: 376 件ウェブページステータス検索Chemie searchBIRD

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1CX4	CRYSTAL STRUCTURE OF A DELETION MUTANT OF THE TYPE II BETA REGULATORY SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP-DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT TYPE II BETA 著者 Diller, T.C, Xuong, N.H, Taylor, S.S. 登録日 1999-08-28 公開日 2001-03-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit. Structure, 9, 2001
6NP6	Crystal structure of the sensor domain of the transcriptional regulator HcpR from Porphyromonas Gingivalis 分子名称: Crp/Fnr family transcriptional regulator, GLYCEROL 著者 Musayev, F.N, Belvin, B.R, Escalante, C.R, Turner, J, Scarsdale, J.N, Lewis, J.P. 登録日 2019-01-17 公開日 2019-06-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Nitrosative Stress Sensing in Porphyromonas gingivalis: Structure and Mechanisms of the Heme Binding Transcriptional Regulator HcpR. Acta Crystallogr D Struct Biol, 75, 2019
6SYG	Crystal structure of the Cyclic Nucleotide-Binding Homology Domain of the human KCNH2 channel 分子名称: Potassium voltage-gated channel subfamily H member 2 著者 Ben-Bassat, A, Giladi, M, Haitin, Y. 登録日 2019-09-27 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of KCNH2 cyclic nucleotide-binding homology domain reveals a functionally vital salt-bridge. J.Gen.Physiol., 152, 2020
2D93	Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6 分子名称: Rap guanine nucleotide exchange factor 6 著者 Inoue, K, Muto, Y, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-12-08 公開日 2006-06-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6 to be published
1U12	M. loti cyclic nucleotide binding domain mutant 分子名称: IODIDE ION, POTASSIUM ION, SULFATE ION, ... 著者 Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H. 登録日 2004-07-14 公開日 2004-11-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Basis of Ligand Activation in a Cyclic Nucleotide Regulated Potassium Channel Cell(Cambridge,Mass.), 119, 2004
4Z07	Co-crystal structure of the tandem CNB (CNB-A/B) domains of human PKG I beta with cGMP 分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, ISOPROPYL ALCOHOL, SULFATE ION, ... 著者 Kim, J.J, Reger, A.S, Arold, S.T, Kim, C. 登録日 2015-03-25 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation. Structure, 24, 2016
1VP6	M.loti ion channel cylic nucleotide binding domain 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, BROMIDE ION, Cyclic-nucleotide binding domain of mesorhizobium loti CNG potassium channel 著者 Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H. 登録日 2004-10-14 公開日 2004-10-26 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel. Cell(Cambridge,Mass.), 119, 2004
5BV6	PKG II's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with cGMP 分子名称: ACETATE ION, CALCIUM ION, GUANOSINE-3',5'-MONOPHOSPHATE, ... 著者 Campbell, J.C, Reger, A.S, Huang, G.Y, Sankaran, B, Kim, J.J, Kim, C.W. 登録日 2015-06-04 公開日 2016-01-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II. J.Biol.Chem., 291, 2016
5C6C	PKG II's Amino Terminal Cyclic Nucleotide Binding Domain (CNB-A) in a complex with cAMP 分子名称: 1,2-ETHANEDIOL, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CADMIUM ION, ... 著者 Campbell, J.C, Reger, A.S, Huang, G.Y, Sankaran, B, Kim, J.J, Kim, C.W. 登録日 2015-06-22 公開日 2016-01-20 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II. J.Biol.Chem., 291, 2016
5C8W	PKG II's Amino Terminal Cyclic Nucleotide Binding Domain (CNB-A) in a complex with cGMP 分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, MALONIC ACID, SODIUM ION, ... 著者 Campbell, J.C, Reger, A.S, Huang, G.Y, Sankaran, B, Kim, J.J, Kim, C.W. 登録日 2015-06-26 公開日 2016-01-20 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II. J.Biol.Chem., 291, 2016
5D1I	Structure of Cyclic nucleotide-binding-like protein from Brucella abortus bv. 1 str. 9-941 分子名称: Cyclic nucleotide-binding protein 著者 He, Z, Dong, J, Li, X, Gao, Y. 登録日 2015-08-04 公開日 2015-09-09 最終更新日 2016-01-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of cyclic nucleotide-binding-like protein from Brucella abortus Biochem.Biophys.Res.Commun., 468, 2015
2N7G	Structure of the cyclic nucleotide-binding homology domain of the hERG channel 分子名称: Potassium voltage-gated channel subfamily H member 2 著者 Li, Y, Ng, H, Li, Q, Kang, C. 登録日 2015-09-10 公開日 2016-05-18 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of the Cyclic Nucleotide-Binding Homology Domain of the hERG Channel and Its Insight into Type 2 Long QT Syndrome Sci Rep, 6, 2016
3U10	Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 著者 Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A. 登録日 2011-09-29 公開日 2011-10-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels. J.Biol.Chem., 286, 2011
3U0Z	Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 著者 Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A. 登録日 2011-09-29 公開日 2011-10-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels. J.Biol.Chem., 286, 2011
3U11	Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 著者 Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A. 登録日 2011-09-29 公開日 2011-10-26 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels. J.Biol.Chem., 286, 2011
3UKV	Structure of the C-linker/CNBHD of zELK channels in P 1 21 1 space group, crystallized in the presence of cAMP 分子名称: Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (Eag-related) family 著者 Brelidze, T.I. 登録日 2011-11-09 公開日 2012-01-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of the carboxy-terminal region of a KCNH channel. Nature, 481, 2012
3UKN	Structure of the C-linker/CNBHD of zELK channels in C 2 2 21 space group 分子名称: Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (Eag-related) family 著者 Brelidze, T.I. 登録日 2011-11-09 公開日 2012-01-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the carboxy-terminal region of a KCNH channel. Nature, 481, 2012
3UKT	Structure of the C-linker/CNBHD of zELK channels in P1 21 1 space group 分子名称: Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (Eag-related) family 著者 Brelidze, T.I. 登録日 2011-11-09 公開日 2012-01-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the carboxy-terminal region of a KCNH channel. Nature, 481, 2012
7LZ4	Crystal structure of A211D mutant of Protein Kinase A RIa subunit, a Carney Complex mutation 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed 著者 Del Rio, J, Wu, J, Taylor, S.S. 登録日 2021-03-08 公開日 2021-05-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (4.155 Å) 主引用文献 Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations. Proc.Natl.Acad.Sci.USA, 118, 2021
2PTM	Structure and rearrangements in the carboxy-terminal region of SpIH channels 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, COBALT HEXAMMINE(III), Hyperpolarization-activated (Ih) channel 著者 Flynn, G.E, Black, K.D, Islas, L.D, Sankaran, B, Zagotta, W.N. 登録日 2007-05-08 公開日 2007-06-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structure and rearrangements in the carboxy-terminal region of SpIH channels. Structure, 15, 2007
2PQQ	Structural Genomics, the crystal structure of the N-terminal domain of a transcriptional regulator from Streptomyces coelicolor A3(2) 分子名称: FORMIC ACID, Putative transcriptional regulator 著者 Tan, K, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2007-05-02 公開日 2007-06-05 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The crystal structure of the N-terminal domain of a transcriptional regulator from Streptomyces coelicolor A3(2) To be Published
2Q0A	Structure and rearrangements in the carboxy-terminal region of SpIH channels 分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 著者 Flynn, G.E, Black, K.D, Islas, L.D, Sankaran, B, Zagotta, W.N. 登録日 2007-05-21 公開日 2007-06-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure and rearrangements in the carboxy-terminal region of SpIH channels. Structure, 15, 2007
5T3N	Sp-2Cl-cAMPS bound to PKAR CBD2 分子名称: (2S,4aR,6R,7R,7aS)-6-(6-amino-2-chloro-9H-purin-9-yl)-7-hydroxy-2-sulfanyltetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-2-one, IODIDE ION, cAMP-dependent protein kinase regulatory subunit 著者 Littler, D.R, Gilson, P. 登録日 2016-08-26 公開日 2016-10-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit. J. Biol. Chem., 291, 2016
2Z69	Crystal Structure of the sensor domain of the transcriptional regulator DNR from Pseudomonas aeruginosa 分子名称: DNR protein 著者 Giardina, G, Johnson, K.A, Di Matteo, A. 登録日 2007-07-24 公開日 2008-03-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR. J.Mol.Biol., 378, 2008
7MBJ	Crystal structure of cGMP dependent protein kinase I alpha (PKG I alpha)CNB-A domain with R177Q mutation 分子名称: cGMP-dependent protein kinase 1 著者 Kim, J.J, Casteel, D.E, Kim, C. 登録日 2021-03-31 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 An auto-inhibited state of protein kinase G and implications for selective activation. Elife, 11, 2022

 

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