PDB: 48062 件ウェブページステータス検索Chemie searchBIRD

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2NOS	MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN (DELTA 114), AMINOGUANIDINE COMPLEX 分子名称: AMINOGUANIDINE, IMIDAZOLE, INDUCIBLE NITRIC OXIDE SYNTHASE, ... 著者 Crane, B.R, Arvai, A.S, Getzoff, E.D, Stuehr, D.J, Tainer, J.A. 登録日 1997-09-28 公開日 1998-10-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The structure of nitric oxide synthase oxygenase domain and inhibitor complexes. Science, 278, 1997
7NWJ	Solution NMR structure of the N-terminal domain of CEP164 (1-109) 分子名称: Centrosomal protein of 164 kDa 著者 van Breugel, M, Rutherford, T.J. 登録日 2021-03-16 公開日 2021-09-15 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies. Structure, 30, 2022
4ORB	Crystal structure of mouse calcineurin 分子名称: CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ... 著者 Ma, L, Li, S.J, Wang, J, Wu, J.W, Wang, Z.X. 登録日 2014-02-11 公開日 2015-05-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.108 Å) 主引用文献 Cooperative autoinhibition and multi-level activation mechanisms of calcineurin To be Published
1PER	THE COMPLEX BETWEEN PHAGE 434 REPRESSION DNA-BINDING DOMAIN AND OPERATOR SITE OR3: STRUCTURAL DIFFERENCES BETWEEN CONSENSUS AND NON-CONSENSUS HALF-SITES 分子名称: DNA (5'-D(*AP*AP*GP*TP*AP*CP*AP*GP*TP*TP*TP*TP*TP*CP*TP*TP*G P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*CP*AP*AP*GP*AP*AP*AP*AP*AP*CP*TP*GP*T P*AP*CP*T)-3'), PROTEIN (434 REPRESSOR) 著者 Rodgers, D.W, Harrison, S.C. 登録日 1993-11-09 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The complex between phage 434 repressor DNA-binding domain and operator site OR3: structural differences between consensus and non-consensus half-sites. Structure, 1, 1993
4OXY	Substrate-binding loop movement with inhibitor PT10 in the tetrameric Mycobacterium tuberculosis enoyl-ACP reductase InhA 分子名称: 5-hexyl-2-(2-nitrophenoxy)phenol, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Li, H.J, Sullivan, T.J, Pan, P, Lai, C.T, Liu, N, Garcia-Diaz, M, Simmerling, C, Tonge, P.J. 登録日 2014-02-09 公開日 2014-04-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3501 Å) 主引用文献 A Structural and Energetic Model for the Slow-Onset Inhibition of the Mycobacterium tuberculosis Enoyl-ACP Reductase InhA. Acs Chem.Biol., 9, 2014
4OSG	Klebsiella pneumoniae complexed with NADPH and 6-ethyl-5-[(3R)-3-[3-methoxyl-5-(pyridine-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (UCP1006) 分子名称: 6-ethyl-5-{(3R)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine, CACODYLATE ION, CALCIUM ION, ... 著者 Lamb, K.M, Anderson, A.C. 登録日 2014-02-12 公開日 2014-12-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structures of Klebsiella pneumoniae Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal Features for Potency and Selectivity. Antimicrob.Agents Chemother., 58, 2014
6W11	The structure of Sulfolobus solfataricus Csa3 in complex with cyclic tetraadenylate (cA4) 分子名称: CRISPR locus-related putative DNA-binding protein Csa3, cA4 著者 Charbonneau, A.A, Gauvin, C.C, Lawrence, C.M. 登録日 2020-03-03 公開日 2021-03-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Cyclic Tetra-Adenylate (cA 4 ) Recognition by Csa3; Implications for an Integrated Class 1 CRISPR-Cas Immune Response in Saccharolobus solfataricus. Biomolecules, 11, 2021
7O0Q	Crystal structure of the human METTL3-METTL14 complex bound to Compound 12 (ADO_AD_066) 分子名称: 3-[4-[(4,4-dimethylpiperidin-1-yl)methyl]phenyl]-8-[6-(methylamino)pyrimidin-4-yl]-1,3,8-triazaspiro[4.5]decan-2-one, ACETATE ION, MAGNESIUM ION, ... 著者 Bedi, R.K, Dolbois, A, Caflisch, A. 登録日 2021-03-26 公開日 2021-09-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Crystal structure of the human METTL3-METTL14 complex bound to Compound 12 (ADO_AD_066) To Be Published
6W12	Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to the Tumor-Associated Tn Antigen 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, C-type lectin domain family 10 member A, CALCIUM ION, ... 著者 Birrane, G, Murphy, P.V, Gabba, A, Luz, J.G. 登録日 2020-03-03 公開日 2021-03-10 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen. Biochemistry, 60, 2021
4OZI	S2 protein complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HLA class II histocompatibility antigen, ... 著者 Petersen, J, Reid, H.H, Rossjohn, J. 登録日 2014-02-16 公開日 2014-04-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014
6W59	Trypanosoma cruzi Malic Enzyme in complex with inhibitor (MEC063) 分子名称: 3,5-bis(fluoranyl)-~{N}-[3-[[4-(trifluoromethyloxy)phenyl]sulfamoyl]phenyl]benzamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Malic enzyme 著者 Mercaldi, G.F, Fagundes, M, Faria, J.N, Cordeiro, A.T. 登録日 2020-03-12 公開日 2021-03-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box. Acs Infect Dis., 7, 2021
5DZG	Crystal Structure of the catalytic nucleophile mutant of VvEG16 in complex with a xyloglucan tetradecasaccharide 分子名称: VvEG16, endo-glucanase, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... 著者 McGregor, N.G.S, Tung, C.C, Van Petegem, F, Brumer, H. 登録日 2015-09-25 公開日 2016-09-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Crystallographic insight into the evolutionary origins of xyloglucan endotransglycosylases and endohydrolases. Plant J., 89, 2017
1PG4	Acetyl CoA Synthetase, Salmonella enterica 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-MONOPHOSPHATE-PROPYL ESTER, CHLORIDE ION, ... 著者 Gulick, A.M, Starai, V.J, Horswill, A.R, Homick, K.M, Escalante-Semerena, J.C. 登録日 2003-05-27 公開日 2003-06-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The 1.75 A Crystal Structure of Acetyl-CoA Synthetase Bound to Adenosine-5'-propylphosphate and Coenzyme A Biochemistry, 42, 2003
2Z9G	Complex structure of SARS-CoV 3C-like protease with PMA 分子名称: 3C-like proteinase, BENZENE, MERCURY (II) ION 著者 Lee, C.C, Wang, A.H. 登録日 2007-09-19 公開日 2007-12-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors. Febs Lett., 581, 2007
4GDX	Crystal Structure of Human Gamma-Glutamyl Transpeptidase--Glutamate complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLUTAMIC ACID, ... 著者 West, M.B, Chen, Y, Wickham, S, Heroux, A, Cahill, K, Hanigan, M.H, Mooers, B.H.M. 登録日 2012-08-01 公開日 2013-09-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Novel Insights into Eukaryotic gamma-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme. J.Biol.Chem., 288, 2013
3E3Q	Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9 分子名称: H-2 class I histocompatibility antigen, L-D alpha chain, QL9 peptide, ... 著者 Colf, L.A, Garcia, K.C. 登録日 2008-08-07 公開日 2008-11-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation. J.Immunol., 181, 2008
2MZE	NMR Solution Structure of the PRO Form of Human Matrilysin (proMMP-7) 分子名称: CALCIUM ION, Matrilysin, ZINC ION 著者 Prior, S.H, Fulcher, Y.G, Van Doren, S.R. 登録日 2015-02-11 公開日 2015-11-11 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Charge-Triggered Membrane Insertion of Matrix Metalloproteinase-7, Supporter of Innate Immunity and Tumors. Structure, 23, 2015
4FZB	Structure of thymidylate synthase ThyX complexed to a new inhibitor 分子名称: 2-hydroxy-3-(4-methoxybenzyl)naphthalene-1,4-dione, DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Basta, T, Boum, Y, Briffotaux, J, Becker, H.F, Lamarre-Jouenne, I, Lambry, J.C, Skouloubris, S, Liebl, U, van Tilbeurgh, H, Graille, M, Myllylkallio, H. 登録日 2012-07-06 公開日 2013-05-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Mechanistic and structural basis for inhibition of thymidylate synthase ThyX. Open Biology, 2, 2012
7NVK	Crystal structure of UBA5 fragment fused to the N-terminus of UFC1 分子名称: Ubiquitin-like modifier-activating enzyme 5,Ubiquitin-fold modifier-conjugating enzyme 1 著者 Manoj Kumar, P, Padala, P, Isupov, M.N, Wiener, R. 登録日 2021-03-15 公開日 2021-09-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.651 Å) 主引用文献 Structural basis for UFM1 transfer from UBA5 to UFC1. Nat Commun, 12, 2021
5AXS	Crystal structure of CdCat-Fn 分子名称: CADMIUM ION, Ferritin light chain, GLYCEROL, ... 著者 Abe, S, Nakajima, H, Kondo, M, Nakane, T, Nakao, T, Ueno, T, Watanabe, Y. 登録日 2015-08-01 公開日 2015-11-18 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Construction of an enterobactin analogue with symmetrically arranged monomer subunits of ferritin Chem.Commun.(Camb.), 51, 2015
1PHF	CRYSTAL STRUCTURES OF METYRAPONE-AND PHENYLIMIDAZOLE-INHIBITED COMPLEXES OF CYTOCHROME P450-CAM 分子名称: 4-PHENYL-1H-IMIDAZOLE, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE 著者 Poulos, T.L. 登録日 1992-07-27 公開日 1993-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structures of metyrapone- and phenylimidazole-inhibited complexes of cytochrome P-450cam. Biochemistry, 26, 1987
2DAE	Solution Structure of the N-terminal CUE Domain in the Human Mitogen-activated Protein Kinase Kinase Kinase 7 Interacting Protein 2 (MAP3K7IP2) 分子名称: KIAA0733 protein 著者 Zhao, C, Kigawa, T, Sato, M, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-12-14 公開日 2007-02-20 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the N-terminal CUE Domain in the Human Mitogen-activated Protein Kinase Kinase Kinase 7 Interacting Protein 2 (MAP3K7IP2) To be Published
2W2M	WT PCSK9-DELTAC BOUND TO WT EGF-A OF LDLR 分子名称: CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR, PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 著者 Bottomley, M.J, Cirillo, A, Orsatti, L, Ruggeri, L, Fisher, T.S, Santoro, J.C, Cummings, R.T, Cubbon, R.M, Lo Surdo, P, Calzetta, A, Noto, A, Baysarowich, J, Mattu, M, Talamo, F, De Francesco, R, Sparrow, C.P, Sitlani, A, Carfi, A. 登録日 2008-11-03 公開日 2008-11-18 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants. J.Biol.Chem., 284, 2009
2N3T	Solution structure of the Rpn1 substrate receptor site toroid 1 (T1) 分子名称: 26S proteasome regulatory subunit RPN1 著者 Chen, X, Walters, K.J. 登録日 2015-06-10 公開日 2016-02-24 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome. Science, 351, 2016
4GF5	Crystal Structure of Calicheamicin Methyltransferase, CalS11 分子名称: CalS11, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION 著者 Helmich, K.E, Singh, S, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Center for Eukaryotic Structural Genomics (CESG) 登録日 2012-08-02 公開日 2012-08-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 to be published

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