4GDX

Crystal Structure of Human Gamma-Glutamyl Transpeptidase--Glutamate complex

Summary for 4GDX

Entry DOI	10.2210/pdb4gdx/pdb
Related	2DBU 2DBW 2DBX 2DG5 2EOW 2EOX 2EOY 2NQO 4GG2 4GG3
Descriptor	Gamma-glutamyltranspeptidase 1 heavy chain, Gamma-glutamyltranspeptidase 1 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	product-enzyme complex, ntn-hydrolase family, glycoprotein, n-glycosylation, cell surface, hydrolase
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type II membrane protein: P19440 P19440
Total number of polymer chains	2
Total formula weight	63000.18
Authors	West, M.B.,Chen, Y.,Wickham, S.,Heroux, A.,Cahill, K.,Hanigan, M.H.,Mooers, B.H.M. (deposition date: 2012-08-01, release date: 2013-09-25, Last modification date: 2023-09-13)
Primary citation	West, M.B.,Chen, Y.,Wickham, S.,Heroux, A.,Cahill, K.,Hanigan, M.H.,Mooers, B.H. Novel Insights into Eukaryotic gamma-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme. J.Biol.Chem., 288:31902-31913, 2013 Cited by PubMed: 24047895 DOI: 10.1074/jbc.M113.498139 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.67 Å)

Structure validation