3E3Q
Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9
Summary for 3E3Q
Entry DOI | 10.2210/pdb3e3q/pdb |
Related | 2E7L 2OI9 3E2H |
Descriptor | H-2 class I histocompatibility antigen, L-D alpha chain, QL9 peptide, T-cell receptor alpha chain V region PHDS58, ... (4 entities in total) |
Functional Keywords | tcr, mhc, high affinity, cross reactivity, glycoprotein, immune response, membrane, mhc i, phosphoprotein, transmembrane, immunoglobulin domain, receptor, immune system |
Biological source | Mus musculus (mouse) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01897 |
Total number of polymer chains | 32 |
Total formula weight | 365724.38 |
Authors | Colf, L.A.,Garcia, K.C. (deposition date: 2008-08-07, release date: 2008-11-04, Last modification date: 2023-08-30) |
Primary citation | Jones, L.L.,Colf, L.A.,Stone, J.D.,Garcia, K.C.,Kranz, D.M. Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation. J.Immunol., 181:6255-6264, 2008 Cited by PubMed: 18941216PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)