PDB: 35712 件ウェブページステータス検索Chemie searchBIRD

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3PRL	Crystal structure of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Bacillus halodurans C-125 分子名称: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, SULFATE ION 著者 Malashkevich, V.N, Toro, R, Seidel, R, Garrett, S, Foti, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2010-11-29 公開日 2010-12-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Bacillus halodurans C-125 To be Published
7RN5	Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic Screen 分子名称: ACETYL GROUP, MAGNESIUM ION, PYROPHOSPHATE, ... 著者 Hruza, A, Strickland, C.L. 登録日 2021-07-29 公開日 2021-09-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic Screen. ACS Med Chem Lett, 12, 2021
3C0K	Crystal Structure of a ribosomal RNA methyltranferase 分子名称: UPF0064 protein yccW 著者 Subramanian, S, Jayaraman, S, Bujnicki, J. 登録日 2008-01-21 公開日 2008-11-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes J.Mol.Biol., 383, 2008
6SNE	crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, LN01 heavy chain, ... 著者 Caillat, C, Pinto, D, Corti, D, Fenwick, C, Pantaleo, G, Weissenhorn, W. 登録日 2019-08-23 公開日 2019-11-06 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01. Cell Host Microbe, 26, 2019
3PT5	Crystal structure of NanS 分子名称: NANS (YJHS), A 9-O-acetyl N-acetylneuraminic acid esterase 著者 Ruane, K.M, Rangarajan, E.S, Proteau, A, Schrag, J.D, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2010-12-02 公開日 2011-05-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural and enzymatic characterization of NanS (YjhS), a 9-O-Acetyl N-acetylneuraminic acid esterase from Escherichia coli O157:H7. Protein Sci., 20, 2011
3CCT	Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors 分子名称: (3R,5R)-7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase 著者 Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. 登録日 2008-02-26 公開日 2008-06-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
3CCZ	Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors 分子名称: (3R,5R)-7-[2-(4-fluorophenyl)-4-{[(1S)-2-hydroxy-1-phenylethyl]carbamoyl}-5-(1-methylethyl)-1H-imidazol-1-yl]-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION 著者 Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. 登録日 2008-02-26 公開日 2008-06-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
3CD5	Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors 分子名称: (3R,5R)-7-[3-(biphenyl-4-ylcarbamoyl)-2-ethyl-5,6,7,8-tetrahydrocyclohepta[b]pyrrol-1(4H)-yl]-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION 著者 Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. 登録日 2008-02-26 公開日 2008-06-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
3PXW	Crystal Structure of Ferrous NO Adduct of MauG in Complex with Pre-Methylamine Dehydrogenase 分子名称: 1,2-ETHANEDIOL, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, ACETATE ION, ... 著者 Yukl, E.T, Goblirsch, B.R, Wilmot, C.M. 登録日 2010-12-10 公開日 2011-03-23 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Crystal Structures of CO and NO Adducts of MauG in Complex with Pre-Methylamine Dehydrogenase: Implications for the Mechanism of Dioxygen Activation. Biochemistry, 50, 2011
3C8R	Contributions of all 20 amino acids at site 96 to stability and structure of T4 lysozyme 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme 著者 Mooers, B.H.M. 登録日 2008-02-13 公開日 2009-02-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme. Protein Sci., 18, 2009
3PZL	The crystal structure of agmatine ureohydrolase of Thermoplasma volcanium 分子名称: Agmatine ureohydrolase, MANGANESE (II) ION 著者 Zhang, Z, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2010-12-14 公開日 2011-01-19 最終更新日 2021-02-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The crystal structure of agmatine ureohydrolase of Thermoplasma volcanium To be Published
6BVD	Structure of Botulinum Neurotoxin Serotype HA Light Chain 分子名称: ACETATE ION, CALCIUM ION, Light Chain, ... 著者 Jin, R, Lam, K. 登録日 2017-12-12 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structural and biochemical characterization of the protease domain of the mosaic botulinum neurotoxin type HA. Pathog Dis, 76, 2018
3BND	Lipoxygenase-1 (Soybean), I553V Mutant 分子名称: FE (III) ION, Seed lipoxygenase-1 著者 Tomchick, D.R. 登録日 2007-12-14 公開日 2008-04-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1. Proc.Natl.Acad.Sci.Usa, 105, 2008
5OP9	The crystal structure of P450 CYP121 in complex with lead compound 7e 分子名称: 4-(imidazol-1-ylmethyl)-3-(4-methoxyphenyl)-1-phenyl-pyrazole, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Levy, C.W. 登録日 2017-08-09 公開日 2018-03-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.455 Å) 主引用文献 Novel Aryl Substituted Pyrazoles as Small Molecule Inhibitors of Cytochrome P450 CYP121A1: Synthesis and Antimycobacterial Evaluation. J. Med. Chem., 60, 2017
3CAQ	Crystal structure of 5beta-reductase (AKR1D1) in complex with NADPH 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3-oxo-5-beta-steroid 4-dehydrogenase, ... 著者 Faucher, F, Cantin, L, Breton, R. 登録日 2008-02-20 公開日 2008-12-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structures of Human Delta4-3-Ketosteroid 5beta-Reductase (AKR1D1) Reveal the Presence of an Alternative Binding Site Responsible for Substrate Inhibition (dagger) (,) (double dagger). Biochemistry, 47, 2008
1O6L	Crystal structure of an activated Akt/protein kinase B (PKB-PIF chimera) ternary complex with AMP-PNP and GSK3 peptide 分子名称: GLYCOGEN SYNTHASE KINASE-3 BETA, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Yang, J, Cron, P, Good, V.M, Thompson, V, Hemmings, B.A, Barford, D. 登録日 2002-10-08 公開日 2002-11-19 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of an Activated Akt/Protein Kinase B Ternary Complex with Gsk-3 Peptide and AMP-Pnp Nat.Struct.Biol., 9, 2002
1O6K	Structure of activated form of PKB kinase domain S474D with GSK3 peptide and AMP-PNP 分子名称: GLYCOGEN SYNTHASE KINASE-3 BETA, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Yang, J, Cron, P, Good, V.M, Thompson, V, Hemmings, B.A, Barford, D. 登録日 2002-10-08 公開日 2002-11-19 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of an Activated Akt/Protein Kinase B Ternary Complex with Gsk-3 Peptide and AMP-Pnp Nat.Struct.Biol., 9, 2002
3PTQ	The crystal structure of rice (Oryza sativa L.) Os4BGlu12 with dinitrophenyl 2-deoxy-2-fluoro-beta-D-glucopyranoside 分子名称: 2,4-dinitrophenyl 2-deoxy-2-fluoro-beta-D-glucopyranoside, Beta-glucosidase Os4BGlu12, GLYCEROL, ... 著者 Sansenya, S, Opassiri, R, Kuaprasert, B, Chen, C.J, Ketudat Cairns, J.R. 登録日 2010-12-03 公開日 2011-05-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The crystal structure of rice (Oryza sativa L.) Os4BGlu12, an oligosaccharide and tuberonic acid glucoside-hydrolyzing beta-glucosidase with significant thioglucohydrolase activity Arch.Biochem.Biophys., 510, 2011
6TCH	Binary complex of 14-3-3 sigma and a high-affinity non-canonical 9-mer peptide binder 分子名称: 14-3-3 protein sigma, CHLORIDE ION, DLY-NVA-PPN-KCJ-SEP-PPN-B3S-BAL-PPN-LYS, ... 著者 Somsen, B.A, Ottmann, C. 登録日 2019-11-06 公開日 2020-07-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Ultra-large chemical libraries for the discovery of high-affinity peptide binders. Nat Commun, 11, 2020
3BVX	GOLGI MANNOSIDASE II D204A catalytic nucleophile mutant complex with Methyl (2-deoxy-2-acetamido-beta-D-glucopyranosyl)-(1->2)-(alpha-D-mannopyranosyl)- (1->3)-[(alpha-D-mannopyranosyl)-(1->6)-(alpha-D-mannopyranosyl)-(1->6)]-beta-D-mannopyranoside 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]methyl beta-D-mannopyranoside, Alpha-mannosidase 2, ... 著者 Kuntz, D.A, Rose, D.R. 登録日 2008-01-07 公開日 2008-07-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant. J.Am.Chem.Soc., 130, 2008
5OTV	Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Cyc/Thr11Hcs 分子名称: Glucagon, Glucagon-like peptide 1 receptor 著者 Mortensen, S. 登録日 2017-08-22 公開日 2018-07-04 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 alpha-Helix or beta-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4. Biochemistry, 57, 2018
5OQM	STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH AND CORE MEDIATOR 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Urlaub, H, Cramer, P. 登録日 2017-08-13 公開日 2018-05-09 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature, 551, 2017
3PNM	Crystal Structure of E.coli Dha kinase DhaK (H56A) 分子名称: PTS-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit dhaK 著者 Shi, R, McDonald, L, Matte, A, Cygler, M, Ekiel, I, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2010-11-19 公開日 2011-01-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural and mechanistic insight into covalent substrate binding by Escherichia coli dihydroxyacetone kinase. Proc.Natl.Acad.Sci.USA, 108, 2011
3PZB	Crystals Structure of Aspartate beta-Semialdehyde Dehydrogenase complex with NADP and D-2,3-Diaminopropionate 分子名称: 1,2-ETHANEDIOL, 3-amino-D-alanine, Aspartate-semialdehyde dehydrogenase, ... 著者 Pavlovsky, A.G, Viola, R.E. 登録日 2010-12-14 公開日 2012-01-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family. Chem.Biol.Drug Des., 79, 2012
6CAY	Crystal structure of the first StART-like domain of Ysp2p/Lam2p in its apo and ergosterol-bound state. 分子名称: ERGOSTEROL, Sterol-binding protein 著者 Horenkamp, F.A, Valverde, D.P, Reinisch, K.M. 登録日 2018-02-01 公開日 2018-02-28 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis for sterol transport by StART-like lipid transfer domains. EMBO J., 37, 2018

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