6TCH
Binary complex of 14-3-3 sigma and a high-affinity non-canonical 9-mer peptide binder
Summary for 6TCH
Entry DOI | 10.2210/pdb6tch/pdb |
Descriptor | 14-3-3 protein sigma, DLY-NVA-PPN-KCJ-SEP-PPN-B3S-BAL-PPN-LYS, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | non-canonical peptide, 14-3-3 protein sigma, protein-peptide interaction, phosphopeptide, non-natural amino acids, protein binding, peptide binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 28116.05 |
Authors | Somsen, B.A.,Ottmann, C. (deposition date: 2019-11-06, release date: 2020-07-01, Last modification date: 2024-01-24) |
Primary citation | Quartararo, A.J.,Gates, Z.P.,Somsen, B.A.,Hartrampf, N.,Ye, X.,Shimada, A.,Kajihara, Y.,Ottmann, C.,Pentelute, B.L. Ultra-large chemical libraries for the discovery of high-affinity peptide binders. Nat Commun, 11:3183-3183, 2020 Cited by PubMed: 32576815DOI: 10.1038/s41467-020-16920-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.801 Å) |
Structure validation
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