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6SNE

crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide

Summary for 6SNE
Entry DOI10.2210/pdb6sne/pdb
DescriptorEnvelope glycoprotein gp160, LN01 light chain, LN01 heavy chain, ... (5 entities in total)
Functional Keywordsgp41, antibody, complex, mper, immune system
Biological sourceHuman immunodeficiency virus 1
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Total number of polymer chains12
Total formula weight228070.57
Authors
Caillat, C.,Pinto, D.,Corti, D.,Fenwick, C.,Pantaleo, G.,Weissenhorn, W. (deposition date: 2019-08-23, release date: 2019-11-06, Last modification date: 2020-07-29)
Primary citationPinto, D.,Fenwick, C.,Caillat, C.,Silacci, C.,Guseva, S.,Dehez, F.,Chipot, C.,Barbieri, S.,Minola, A.,Jarrossay, D.,Tomaras, G.D.,Shen, X.,Riva, A.,Tarkowski, M.,Schwartz, O.,Bruel, T.,Dufloo, J.,Seaman, M.S.,Montefiori, D.C.,Lanzavecchia, A.,Corti, D.,Pantaleo, G.,Weissenhorn, W.
Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Cell Host Microbe, 26:623-637.e8, 2019
Cited by
PubMed: 31653484
DOI: 10.1016/j.chom.2019.09.016
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.9 Å)
Structure validation

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