3HD7
 
 | | HELICAL EXTENSION OF THE NEURONAL SNARE COMPLEX INTO THE MEMBRANE, spacegroup C 1 2 1 | | 分子名称: | SULFATE ION, Synaptosomal-associated protein 25, Syntaxin-1A, ... | | 著者 | Stein, A, Weber, G, Wahl, M.C, Jahn, R. | | 登録日 | 2009-05-07 | | 公開日 | 2009-07-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Helical extension of the neuronal SNARE complex into the membrane
Nature, 460, 2009
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3IPD
 | | Helical extension of the neuronal SNARE complex into the membrane, spacegroup I 21 21 21 | | 分子名称: | Synaptosomal-associated protein 25, Syntaxin-1A, Vesicle-associated membrane protein 2 | | 著者 | Stein, A, Weber, G, Wahl, M.C, Jahn, R. | | 登録日 | 2009-08-17 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (4.8 Å) | | 主引用文献 | Helical extension of the neuronal SNARE complex into the membrane
Nature, 460, 2009
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1PMA
 | | PROTEASOME FROM THERMOPLASMA ACIDOPHILUM | | 分子名称: | PROTEASOME | | 著者 | Loewe, J, Stock, D, Jap, B, Zwickl, P, Baumeister, W, Huber, R. | | 登録日 | 1994-12-19 | | 公開日 | 1996-06-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution.
Science, 268, 1995
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4GL5
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4GL7
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3O96
 | | Crystal Structure of Human AKT1 with an Allosteric Inhibitor | | 分子名称: | 1-(1-(4-(7-phenyl-1H-imidazo[4,5-g]quinoxalin-6-yl)benzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one, RAC-alpha serine/threonine-protein kinase | | 著者 | Voegtli, W.C, Wu, W.-I, Lord-Ondash, H.A, Dizon, F.P, Vigers, G.P.A, Brandhuber, B.J. | | 登録日 | 2010-08-03 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of human AKT1 with an allosteric inhibitor reveals a new mode of kinase inhibition.
Plos One, 5, 2010
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4GLI
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4EJN
 | | Crystal structure of autoinhibited form of AKT1 in complex with N-(4-(5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl)benzyl)-3-fluorobenzamide | | 分子名称: | 1,2-ETHANEDIOL, 2-BUTANOL, N-(4-{5-[3-(acetylamino)phenyl]-2-(2-aminopyridin-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl}benzyl)-3-fluorobenzamide, ... | | 著者 | Eathiraj, S. | | 登録日 | 2012-04-06 | | 公開日 | 2012-05-23 | | 最終更新日 | 2013-01-02 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Discovery and optimization of a series of 3-(3-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amines: orally bioavailable, selective, and potent ATP-independent Akt inhibitors.
J.Med.Chem., 55, 2012
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3RK3
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3RL0
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3RK2
 | | Truncated SNARE complex | | 分子名称: | CALCIUM ION, Synaptosomal-associated protein 25, Syntaxin-1A, ... | | 著者 | Kuemmel, D, Reinisch, K.M. | | 登録日 | 2011-04-17 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Complexin cross-links prefusion SNAREs into a zigzag array.
Nat.Struct.Mol.Biol., 18, 2011
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8RJ3
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8T9L
 | | Pom34-Pom152 membrane attachment site yeast NPC | | 分子名称: | Nucleoporin POM152, Nucleoporin POM34 | | 著者 | Akey, C.W, Echeverria, I, Ouch, C, Fernandez-Martinez, J, Rout, M.P. | | 登録日 | 2023-06-24 | | 公開日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Implications of a multiscale structure of the yeast nuclear pore complex.
Mol.Cell, 83, 2023
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8TTB
 | | Cryo-EM structure of the PP2A:B55-ARPP19 complex | | 分子名称: | FE (III) ION, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | | 著者 | Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. | | 登録日 | 2023-08-13 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19.
Nature, 625, 2024
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8UO1
 | | CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class Q) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-10-19 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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7LCU
 | | X-ray structure of Furin bound to BOS-318, a small molecule inhibitor | | 分子名称: | (1-{[2-(3,5-dichlorophenyl)-6-{[2-(4-methylpiperazin-1-yl)pyrimidin-5-yl]oxy}pyridin-4-yl]methyl}piperidin-4-yl)acetic acid, 1,2-ETHANEDIOL, CALCIUM ION, ... | | 著者 | Campobasso, N, Reid, R. | | 登録日 | 2021-01-11 | | 公開日 | 2022-01-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease.
Cell Chem Biol, 29, 2022
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7NH4
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7NH5
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1DO3
 | | CARBONMONOXY-MYOGLOBIN (MUTANT L29W) AFTER PHOTOLYSIS AT T>180K | | 分子名称: | CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Ostermann, A, Waschipky, R, Parak, F.G, Nienhaus, G.U. | | 登録日 | 1999-12-18 | | 公開日 | 2000-01-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Ligand binding and conformational motions in myoglobin.
Nature, 404, 2000
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1DO7
 | | CARBONMONOXY-MYOGLOBIN (MUTANT L29W) REBINDING STRUCTURE AFTER PHOTOLYSIS AT T< 180K | | 分子名称: | CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Ostermann, A, Waschipky, R, Parak, F.G, Nienhaus, G.U. | | 登録日 | 1999-12-19 | | 公開日 | 2000-01-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Ligand binding and conformational motions in myoglobin.
Nature, 404, 2000
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1DO1
 | | CARBONMONOXY-MYOGLOBIN MUTANT L29W AT 105K | | 分子名称: | CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Ostermann, A, Waschipky, R, Parak, F.G, Nienhaus, G.U. | | 登録日 | 1999-12-18 | | 公開日 | 2000-01-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Ligand binding and conformational motions in myoglobin.
Nature, 404, 2000
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7NWL
 | | Cryo-EM structure of human integrin alpha5beta1 (open form) in complex with fibronectin and TS2/16 Fv-clasp | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-5, ... | | 著者 | Schumacher, S, Dedden, D, Vazquez Nunez, R, Matoba, K, Takagi, J, Biertumpfel, C, Mizuno, N. | | 登録日 | 2021-03-17 | | 公開日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand.
Sci Adv, 7, 2021
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1DO4
 | | CARBONMONOXY-MYOGLOBIN (MUTANT L29W) AFTER PHOTOLYSIS AT T<180K | | 分子名称: | CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Ostermann, A, Waschipky, R, Parak, F.G, Nienhaus, G.U. | | 登録日 | 1999-12-18 | | 公開日 | 2000-01-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Ligand binding and conformational motions in myoglobin.
Nature, 404, 2000
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3R9C
 | | Crystal structure of Mycobacterium smegmatis CYP164A2 with Econazole bound | | 分子名称: | 1,2-ETHANEDIOL, 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, Cytochrome P450 164A2, ... | | 著者 | Agnew, C.R.J, Kelly, S.L, Brady, R.L. | | 登録日 | 2011-03-25 | | 公開日 | 2012-03-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | An enlarged, adaptable active site in CYP164 family P450 enzymes, the sole P450 in Mycobacterium leprae.
Antimicrob.Agents Chemother., 56, 2012
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8CTK
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