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5E3M
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BU of 5e3m by Molmil
Crystal structure of Fis bound to 27bp DNA F35 (AAATTAGTTTGAATCTCGAGCTAATTT)
分子名称: DNA (27-MER), DNA-binding protein Fis
著者Stella, S, Hancock, S.P, Cascio, D, Johnson, R.C.
登録日2015-10-03
公開日2016-03-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.886 Å)
主引用文献DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nucleoid Protein Fis.
Plos One, 11, 2016
5EB1
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BU of 5eb1 by Molmil
the YfiB-YfiR complex
分子名称: SULFATE ION, YfiB, YfiR
著者Xu, M, Yang, X, Yang, X.-A, Zhou, L, Liu, T.-Z, Fan, Z, Jiang, T.
登録日2015-10-17
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
Protein Cell, 7, 2016
5F74
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BU of 5f74 by Molmil
Crystal structure of ChREBP:14-3-3 complex bound with AMP
分子名称: 14-3-3 protein beta/alpha, ADENOSINE MONOPHOSPHATE, Carbohydrate-responsive element-binding protein
著者Jung, H, Uyeda, K.
登録日2015-12-07
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP): ROLE OF AMP AS AN ALLOSTERIC INHIBITOR.
J.Biol.Chem., 291, 2016
5F12
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BU of 5f12 by Molmil
WrbA in complex with FMN under crystallization conditions of WrbA-FMN-BQ structure (4YQE)
分子名称: FLAVIN MONONUCLEOTIDE, NAD(P)H dehydrogenase (quinone)
著者Degtjarik, O, Brynda, J, Ettrichova, O, Kuta Smatanova, I, Carey, J, Ettrich, R.
登録日2015-11-29
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Quantum Calculations Indicate Effective Electron Transfer between FMN and Benzoquinone in a New Crystal Structure of Escherichia coli WrbA.
J.Phys.Chem.B, 120, 2016
5F6F
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BU of 5f6f by Molmil
S. aureus MepR G34R Mutant
分子名称: MarR family regulatory protein
著者Newman, C.E, Birukou, I, Brennan, R.G.
登録日2015-12-05
公開日2016-12-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.751 Å)
主引用文献S. aureus MepR G34R Mutant
To Be Published
8BPB
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BU of 8bpb by Molmil
Cryo-EM structure of the human SIN3B histone deacetylase core complex at 2.8 Angstrom
分子名称: ACETATE ION, CALCIUM ION, Histone deacetylase 2, ...
著者Wan, M.S.M, Muhammad, R, Koliopolous, M.G, Alfieri, C.
登録日2022-11-16
公開日2023-05-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex.
Nat Commun, 14, 2023
8BPC
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BU of 8bpc by Molmil
Cryo-EM structure of the human SIN3B histone deacetylase core complex with SAHA at 2.8 Angstrom
分子名称: CALCIUM ION, Histone deacetylase 2, Isoform 2 of Paired amphipathic helix protein Sin3b, ...
著者Wan, M.S.M, Muhammad, R, Koliopolous, M.G, Alfieri, C.
登録日2022-11-16
公開日2023-05-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex.
Nat Commun, 14, 2023
5FO5
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BU of 5fo5 by Molmil
Structure of the DNA-binding domain of Escherichia coli methionine biosynthesis regulator MetR
分子名称: 1,2-ETHANEDIOL, HTH-TYPE TRANSCRIPTIONAL REGULATOR METR, MAGNESIUM ION
著者Punekar, A.S, Porter, J, Urbanowski, M.L, Stauffer, G.V, Carr, S.B, Phillips, S.E.
登録日2015-11-18
公開日2016-06-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structural Basis for DNA Recognition by the Transcription Regulator Metr.
Acta Crystallogr.,Sect.F, 72, 2016
5FFZ
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BU of 5ffz by Molmil
S. aureus MepR bound to ethidium bromide
分子名称: ETHIDIUM, MarR family regulatory protein, POTASSIUM ION
著者Birukou, I, Newman, C.E, Brennan, R.G.
登録日2015-12-19
公開日2016-12-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.585 Å)
主引用文献S. aureus MepR bound to ethidium bromide
To Be Published
5FFX
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BU of 5ffx by Molmil
S. aureus MepR G34K Mutant
分子名称: GLYCEROL, MarR family regulatory protein, SULFATE ION
著者Newman, C.E, Birukou, I, Brennan, R.G.
登録日2015-12-19
公開日2016-12-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献S. aureus MepR G34K Mutant
To Be Published
3BTJ
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BU of 3btj by Molmil
crystal structure of QacR(E58Q) bound to dequalinium
分子名称: DEQUALINIUM, HTH-type transcriptional regulator qacR, SULFATE ION
著者Schumacher, M.A, Schuman, J.T, Brennan, R.G.
登録日2007-12-28
公開日2008-08-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization
Biochemistry, 47, 2008
5FCT
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BU of 5fct by Molmil
Mouse thymidylate synthase in ternary complex with FdUMP and methylenetetrahydrofolate.
分子名称: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Thymidylate synthase
著者Dowiercial, A, Wilk, P, Jarmula, A, Rode, W.
登録日2015-12-15
公開日2016-10-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme
Struct Chem, 2016
5FB2
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BU of 5fb2 by Molmil
S. aureus MepR F27L Mutant bound to oligodeoxyribonucleotide
分子名称: DNA (5'-D(*CP*GP*TP*TP*A)-3'), GLYCEROL, MarR family regulatory protein
著者Birukou, I, Newman, C.E, Brennan, R.G.
登録日2015-12-13
公開日2016-12-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献S. aureus MepR F27L Mutant bound to oligodeoxyribonucleotide
To Be Published
5DV4
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BU of 5dv4 by Molmil
Crystal structure of human CNOT6L in complex with neomycin
分子名称: CCR4-NOT transcription complex subunit 6-like, NEOMYCIN, SULFATE ION
著者Zhang, Q, Bartlam, M.
登録日2015-09-21
公開日2016-10-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for inhibition of the deadenylase activity of human CNOT6L
Febs Lett., 590, 2016
5EB3
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BU of 5eb3 by Molmil
VB6-bound protein
分子名称: 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol, SULFATE ION, YfiR
著者Xu, M, Yang, X, Yang, X.-A, Zhou, L, Liu, T.-Z, Fan, Z, Jiang, T.
登録日2015-10-17
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
Protein Cell, 7, 2016
3BT9
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BU of 3bt9 by Molmil
crystal structure of QacR(E57Q) bound to Dequalinium
分子名称: DEQUALINIUM, HTH-type transcriptional regulator qacR, SULFATE ION
著者Shumacher, M.A, Schuman, J.T, Brennan, R.G.
登録日2007-12-28
公開日2008-08-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization
Biochemistry, 47, 2008
2OZ6
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BU of 2oz6 by Molmil
Crystal Structure of Virulence Factor Regulator from Pseudomonas aeruginosa in complex with cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Virulence Factor Regulator
著者Cordes, T.J, Bright, A.R, Forest, K.T.
登録日2007-02-24
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of the Pseudomonas aeruginosa Virulence Factor Regulator.
J.Bacteriol., 193, 2011
5JWK
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BU of 5jwk by Molmil
Factor Inhibiting HIF D201E in Complex with Fe, and Alpha-Ketoglutarate
分子名称: 2-OXOGLUTARIC ACID, DI(HYDROXYETHYL)ETHER, FE (II) ION, ...
著者Taabazuing, C.Y, Garman, S.C, Knapp, M.J, Eron, S.
登録日2016-05-12
公開日2017-05-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Factor Inhibiting HIF D201E in Complex with Fe, and Alpha-Ketoglutarate
To Be Published
1PD8
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BU of 1pd8 by Molmil
Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine Antifolate Complex with Human Dihydrofolate Reductase
分子名称: 2,4-DIAMINO-5-METHYL-6-[(3,4,5-TRIMETHOXY-N-METHYLANILINO)METHYL]PYRIDO[2,3-D]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Cody, V, Luft, J.R, Pangborn, W, Gangjee, A.
登録日2003-05-19
公開日2003-12-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase.
Acta Crystallogr.,Sect.D, 59, 2003
1PDB
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BU of 1pdb by Molmil
Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine Antifolate Complex with Human Dihydrofolate Reductase
分子名称: Dihydrofolate reductase
著者Cody, V, Luft, J.R, Pangborn, W, Gangjee, A.
登録日2003-05-19
公開日2003-12-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase.
Acta Crystallogr.,Sect.D, 59, 2003
1PD9
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BU of 1pd9 by Molmil
Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine antifolate Complex with Human Dihydrofolate Reductase
分子名称: 2,4-DIAMINO-5-METHYL-6-[(3,4,5-TRIMETHOXY-N-METHYLANILINO)METHYL]PYRIDO[2,3-D]PYRIMIDINE, Dihydrofolate reductase, SULFATE ION
著者Cody, V, Luft, J.R, Pangborn, W, Gangjee, A.
登録日2003-05-19
公開日2003-12-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase.
Acta Crystallogr.,Sect.D, 59, 2003
8GXS
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BU of 8gxs by Molmil
PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X.
登録日2022-09-21
公開日2022-11-02
実験手法ELECTRON MICROSCOPY (4.16 Å)
主引用文献Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
8GXQ
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BU of 8gxq by Molmil
PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y.
登録日2022-09-21
公開日2022-11-02
実験手法ELECTRON MICROSCOPY (5.04 Å)
主引用文献Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
2R3A
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BU of 2r3a by Molmil
Methyltransferase domain of human suppressor of variegation 3-9 homolog 2
分子名称: Histone-lysine N-methyltransferase SUV39H2, S-ADENOSYLMETHIONINE, SERINE, ...
著者Lunin, V.V, Wu, H, Zeng, H, Ren, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Min, J, Structural Genomics Consortium (SGC)
登録日2007-08-29
公開日2007-09-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural biology of human H3K9 methyltransferases
Plos One, 5, 2010
2QQF
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BU of 2qqf by Molmil
Hst2 bound to ADP-HPD and Acetylated histone H4
分子名称: 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Histone H4, NAD-dependent deacetylase HST2, ...
著者Marmorstein, R, Sanders, B.D, Zhao, K, Slama, J.
登録日2007-07-26
公開日2007-10-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes.
Mol.Cell, 25, 2007

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