2R3A
Methyltransferase domain of human suppressor of variegation 3-9 homolog 2
Summary for 2R3A
Entry DOI | 10.2210/pdb2r3a/pdb |
Descriptor | Histone-lysine N-methyltransferase SUV39H2, ZINC ION, S-ADENOSYLMETHIONINE, ... (5 entities in total) |
Functional Keywords | histone h3-k9 methyltransferase 2, histone-lysine n-methyltransferase, h3 lysine-9 specific 2, alternative splicing, cell cycle, chromatin regulator, chromosomal protein, differentiation, nucleus, repressor, s-adenosyl-l-methionine, telomere, transcription, transcription regulation, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (By similarity): Q9H5I1 |
Total number of polymer chains | 1 |
Total formula weight | 34745.71 |
Authors | Lunin, V.V.,Wu, H.,Zeng, H.,Ren, H.,Loppnau, P.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Plotnikov, A.N.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2007-08-29, release date: 2007-09-11, Last modification date: 2023-08-30) |
Primary citation | Wu, H.,Min, J.,Lunin, V.V.,Antoshenko, T.,Dombrovski, L.,Zeng, H.,Allali-Hassani, A.,Campagna-Slater, V.,Vedadi, M.,Arrowsmith, C.H.,Plotnikov, A.N.,Schapira, M. Structural biology of human H3K9 methyltransferases Plos One, 5:e8570-e8570, 2010 Cited by PubMed: 20084102DOI: 10.1371/journal.pone.0008570 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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